Ephrin B reverse signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations EFNB2 0.023 0.007 -9999.0 0.0 -9999.0 0.0 0.0 EPHB2 0.027 0.033 0.257 20.0 -9999.0 0.0 20.0 EFNB1 -0.004 0.037 -9999.0 0.0 -0.424 7.0 7.0 mol:GTP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.079 0.175 -9999.0 0.0 -0.3 390.0 390.0 Ephrin B2/EPHB1-2 -0.098 0.181 0.209 1.0 -0.325 401.0 402.0 neuron projection morphogenesis -0.085 0.16 -9999.0 0.0 -0.287 390.0 390.0 Ephrin B1/EPHB1-2/Tiam1 -0.09 0.181 -9999.0 0.0 -0.316 396.0 396.0 DNM1 0.02 0.049 0.268 1.0 -0.572 7.0 8.0 cell-cell signaling -0.001 0.003 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K4 -0.023 0.118 -9999.0 0.0 -0.552 46.0 46.0 YES1 -0.025 0.171 -9999.0 0.0 -0.765 51.0 51.0 Ephrin B1/EPHB1-2/NCK2 -0.091 0.181 -9999.0 0.0 -0.316 399.0 399.0 PI3K 0.006 0.13 -9999.0 0.0 -0.518 55.0 55.0 mol:GDP -0.09 0.179 -9999.0 0.0 -0.313 396.0 396.0 ITGA2B 0.033 0.061 0.257 52.0 -0.57 3.0 55.0 endothelial cell proliferation 0.029 0.01 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.025 0.169 -9999.0 0.0 -0.762 50.0 50.0 MAP3K7 -0.024 0.126 -9999.0 0.0 -0.57 49.0 49.0 FGR -0.022 0.169 -9999.0 0.0 -0.762 50.0 50.0 TIAM1 0.025 0.015 0.257 4.0 -9999.0 0.0 4.0 PIK3R1 0.018 0.055 -9999.0 0.0 -0.57 9.0 9.0 RGS3 0.024 0.003 -9999.0 0.0 -9999.0 0.0 0.0 cell adhesion -0.009 0.135 -9999.0 0.0 -0.521 52.0 52.0 LYN -0.022 0.166 -9999.0 0.0 -0.751 50.0 50.0 Ephrin B1/EPHB1-2/Src Family Kinases -0.028 0.158 -9999.0 0.0 -0.712 51.0 51.0 Ephrin B1/EPHB1-2 -0.024 0.133 -9999.0 0.0 -0.63 46.0 46.0 SRC -0.021 0.168 -9999.0 0.0 -0.75 51.0 51.0 ITGB3 0.005 0.107 0.257 4.0 -0.57 34.0 38.0 EPHB1 -0.206 0.289 0.266 1.0 -0.57 402.0 403.0 EPHB4 0.024 0.004 -9999.0 0.0 -9999.0 0.0 0.0 RAC1 0.024 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Ephrin B2/EPHB4 0.03 0.01 -9999.0 0.0 -9999.0 0.0 0.0 alphaIIb/beta3 Integrin 0.026 0.092 -9999.0 0.0 -0.416 37.0 37.0 BLK -0.021 0.174 -9999.0 0.0 -0.778 48.0 48.0 HCK -0.021 0.168 -9999.0 0.0 -0.75 51.0 51.0 regulation of stress fiber formation 0.09 0.179 0.313 399.0 -9999.0 0.0 399.0 MAPK8 -0.025 0.122 -9999.0 0.0 -0.538 48.0 48.0 Ephrin B1/EPHB1-2/RGS3 -0.09 0.181 -9999.0 0.0 -0.316 399.0 399.0 endothelial cell migration -0.018 0.108 -9999.0 0.0 -0.511 42.0 42.0 NCK2 0.024 0.003 -9999.0 0.0 -9999.0 0.0 0.0 PTPN13 0.009 0.111 -9999.0 0.0 -0.684 26.0 26.0 regulation of focal adhesion formation 0.09 0.179 0.313 399.0 -9999.0 0.0 399.0 chemotaxis 0.09 0.179 0.313 399.0 -9999.0 0.0 399.0 PIK3CA 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GTP -0.081 0.168 -9999.0 0.0 -0.294 390.0 390.0 angiogenesis -0.025 0.134 -9999.0 0.0 -0.62 48.0 48.0 LCK -0.021 0.171 -9999.0 0.0 -0.765 50.0 50.0