Glypican 1 network Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations GPC1/FGF2 dimer/FGFR1 dimer -0.1 0.187 -9999.0 0.0 -0.367 317.0 317.0 fibroblast growth factor receptor signaling pathway -0.1 0.186 -9999.0 0.0 -0.365 317.0 317.0 LAMA1 -0.036 0.18 0.257 3.0 -0.57 105.0 108.0 PRNP 0.015 0.071 -9999.0 0.0 -0.57 15.0 15.0 GPC1/SLIT2 -0.013 0.14 -9999.0 0.0 -0.411 111.0 111.0 SMAD2 -0.0 0.067 0.246 1.0 -0.332 38.0 39.0 GPC1/PrPc/Cu2+ 0.026 0.05 -9999.0 0.0 -0.361 16.0 16.0 GPC1/Laminin alpha1 -0.013 0.141 0.366 1.0 -0.4 116.0 117.0 TDGF1 0.017 0.059 0.257 1.0 -0.57 10.0 11.0 CRIPTO/GPC1 0.03 0.049 -9999.0 0.0 -0.422 11.0 11.0 APP/GPC1 0.035 0.021 0.196 7.0 -0.422 1.0 8.0 mol:NO 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 YES1 0.005 0.04 -9999.0 0.0 -0.363 11.0 11.0 FLT1 0.023 0.006 -9999.0 0.0 -9999.0 0.0 0.0 GPC1/TGFB/TGFBR1/TGFBR2 0.033 0.08 -9999.0 0.0 -0.363 39.0 39.0 SERPINC1 0.03 0.049 0.257 45.0 -9999.0 0.0 45.0 FYN 0.004 0.043 -9999.0 0.0 -0.361 13.0 13.0 FGR 0.005 0.04 -9999.0 0.0 -0.363 11.0 11.0 positive regulation of MAPKKK cascade 0.01 0.083 0.265 4.0 -0.352 28.0 32.0 SLIT2 -0.037 0.179 -9999.0 0.0 -0.57 105.0 105.0 GPC1/NRG -0.107 0.2 -9999.0 0.0 -0.367 360.0 360.0 NRG1 -0.139 0.262 0.257 4.0 -0.57 280.0 284.0 GPC1/VEGF165 homodimer/VEGFR1 homodimer 0.046 0.026 -9999.0 0.0 -0.364 1.0 1.0 LYN 0.005 0.036 -9999.0 0.0 -0.363 8.0 8.0 mol:Spermine 0.006 0.017 -9999.0 0.0 -0.419 1.0 1.0 cell growth -0.1 0.186 -9999.0 0.0 -0.365 317.0 317.0 BMP signaling pathway -0.025 0.027 0.57 1.0 -0.256 7.0 8.0 SRC 0.005 0.04 -9999.0 0.0 -0.363 11.0 11.0 TGFBR1 0.024 0.008 0.257 1.0 -9999.0 0.0 1.0 mol:Cu2+ -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PLA2G2A -0.139 0.273 0.257 27.0 -0.57 294.0 321.0 GPC1 0.025 0.027 0.257 7.0 -0.57 1.0 8.0 TGFBR1 (dimer) 0.024 0.008 0.256 1.0 -9999.0 0.0 1.0 VEGFA 0.025 0.02 0.257 7.0 -9999.0 0.0 7.0 BLK 0.02 0.066 -9999.0 0.0 -0.371 13.0 13.0 HCK 0.007 0.043 -9999.0 0.0 -0.363 11.0 11.0 FGF2 -0.201 0.288 -9999.0 0.0 -0.57 393.0 393.0 FGFR1 0.016 0.049 -9999.0 0.0 -0.57 7.0 7.0 VEGFR1 homodimer 0.023 0.006 -9999.0 0.0 -9999.0 0.0 0.0 TGFBR2 0.002 0.112 -9999.0 0.0 -0.57 38.0 38.0 cell death 0.035 0.021 0.195 7.0 -0.421 1.0 8.0 ATIII/GPC1 0.037 0.04 -9999.0 0.0 -0.426 1.0 1.0 PLA2G2A/GPC1 -0.096 0.21 -9999.0 0.0 -0.405 316.0 316.0 LCK 0.006 0.061 -9999.0 0.0 -0.362 22.0 22.0 neuron differentiation -0.107 0.199 -9999.0 0.0 -0.366 360.0 360.0 PrPc/Cu2+ 0.011 0.052 -9999.0 0.0 -0.419 15.0 15.0 APP 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0 TGFBR2 (dimer) 0.002 0.111 -9999.0 0.0 -0.57 38.0 38.0