Ephrin B reverse signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations EFNB2 0.026 0.058 -9999.0 0.0 -0.542 5.0 5.0 EPHB2 0.043 0.038 -9999.0 0.0 -9999.0 0.0 0.0 EFNB1 0.016 0.027 -9999.0 0.0 -0.403 2.0 2.0 mol:GTP -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.048 0.18 -9999.0 0.0 -0.283 180.0 180.0 Ephrin B2/EPHB1-2 -0.074 0.186 -9999.0 0.0 -0.311 190.0 190.0 neuron projection morphogenesis -0.06 0.161 -9999.0 0.0 -0.271 180.0 180.0 Ephrin B1/EPHB1-2/Tiam1 -0.059 0.183 -9999.0 0.0 -0.296 186.0 186.0 DNM1 0.035 0.008 -9999.0 0.0 -9999.0 0.0 0.0 cell-cell signaling -0.001 0.003 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K4 -0.057 0.182 -9999.0 0.0 -0.569 56.0 56.0 YES1 -0.069 0.257 -9999.0 0.0 -0.796 56.0 56.0 Ephrin B1/EPHB1-2/NCK2 -0.06 0.183 -9999.0 0.0 -0.295 187.0 187.0 PI3K -0.045 0.22 -9999.0 0.0 -0.479 92.0 92.0 mol:GDP -0.06 0.181 -9999.0 0.0 -0.293 186.0 186.0 ITGA2B 0.034 0.012 -9999.0 0.0 -9999.0 0.0 0.0 endothelial cell proliferation 0.038 0.046 -9999.0 0.0 -0.309 7.0 7.0 FYN -0.071 0.256 -9999.0 0.0 -0.794 56.0 56.0 MAP3K7 -0.058 0.191 -9999.0 0.0 -0.598 56.0 56.0 FGR -0.065 0.256 -9999.0 0.0 -0.791 56.0 56.0 TIAM1 0.035 0.013 -9999.0 0.0 -9999.0 0.0 0.0 PIK3R1 -0.02 0.166 -9999.0 0.0 -0.542 47.0 47.0 RGS3 0.034 0.005 -9999.0 0.0 -9999.0 0.0 0.0 cell adhesion -0.046 0.198 -9999.0 0.0 -0.554 56.0 56.0 LYN -0.065 0.252 -9999.0 0.0 -0.781 56.0 56.0 Ephrin B1/EPHB1-2/Src Family Kinases -0.071 0.238 -9999.0 0.0 -0.738 57.0 57.0 Ephrin B1/EPHB1-2 -0.061 0.206 -9999.0 0.0 -0.643 56.0 56.0 SRC -0.064 0.255 -9999.0 0.0 -0.78 57.0 57.0 ITGB3 0.035 0.019 -9999.0 0.0 -9999.0 0.0 0.0 EPHB1 -0.179 0.279 -9999.0 0.0 -0.541 191.0 191.0 EPHB4 0.036 0.032 -9999.0 0.0 -0.542 1.0 1.0 RAC1 0.034 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Ephrin B2/EPHB4 0.039 0.046 -9999.0 0.0 -0.31 7.0 7.0 alphaIIb/beta3 Integrin 0.05 0.019 -9999.0 0.0 -9999.0 0.0 0.0 BLK -0.077 0.259 -9999.0 0.0 -0.8 56.0 56.0 HCK -0.065 0.254 -9999.0 0.0 -0.784 56.0 56.0 regulation of stress fiber formation 0.06 0.181 0.293 187.0 -9999.0 0.0 187.0 MAPK8 -0.056 0.177 -9999.0 0.0 -0.545 57.0 57.0 Ephrin B1/EPHB1-2/RGS3 -0.06 0.184 -9999.0 0.0 -0.297 185.0 185.0 endothelial cell migration -0.05 0.172 0.264 1.0 -0.51 58.0 59.0 NCK2 0.035 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PTPN13 -0.024 0.194 -9999.0 0.0 -0.649 45.0 45.0 regulation of focal adhesion formation 0.06 0.181 0.293 187.0 -9999.0 0.0 187.0 chemotaxis 0.06 0.181 0.294 186.0 -9999.0 0.0 186.0 PIK3CA 0.033 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GTP -0.053 0.171 -9999.0 0.0 -0.277 180.0 180.0 angiogenesis -0.061 0.204 -9999.0 0.0 -0.639 56.0 56.0 LCK -0.061 0.258 -9999.0 0.0 -0.783 57.0 57.0