Hybridization REF	p	difference	q	subclass
Composite Element REF	p	difference	q	subclass
PGR|PR	4.80370994236333e-41	3.81777397349738	6.82126811815593e-39	1
ESR1|ER-ALPHA	2.14161089515909e-22	2.39108157143707	1.01369582370864e-20	1
GATA3|GATA3	5.01730221695825e-20	1.10836265138377	1.18742819134679e-18	1
PDCD4|PDCD4	1.28301626009161e-08	1.08700028973037	5.35847967450025e-08	1
MAPK1 MAPK3|MAPK_PT202_Y204	3.95561089963719e-12	0.889899309799162	4.32074421344985e-11	1
AR|AR	5.31594331910725e-14	0.780716308096582	7.54863951313229e-13	1
INPP4B|INPP4B	2.31569876975356e-10	0.744623423731108	1.49467829684093e-09	1
BCL2|BCL-2	1.43978776596908e-09	0.730035745848261	7.30178081312891e-09	1
ESR1|ER-ALPHA_PS118	4.59959395937836e-12	0.681575637805629	4.66530244451234e-11	1
KDR|VEGFR2	2.59354850095604e-08	0.60908307190833	1.04795256517954e-07	1
CDH1|E-CADHERIN	0.00012261372047581	0.493290446691391	0.000280824972702662	1
CTNNB1|BETA-CATENIN	2.6567811511594e-08	0.487061071372328	1.04795256517954e-07	1
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	2.99448744716558e-06	0.47276641681495	8.50434434995025e-06	1
TP53BP1|53BP1	3.85595805841688e-13	0.453416197165529	4.97769131177452e-12	1
EEF2K|EEF2K	3.44525511850901e-10	0.427577532520439	2.1192909627847e-09	1
STAT5A|STAT5-ALPHA	9.8774209449259e-05	0.372096012699366	0.000233765629029913	1
FRAP1|MTOR	4.86135851937791e-07	0.371869089124698	1.56889297670833e-06	1
RB1|RB_PS807_S811	2.75538647877575e-05	0.323404650257032	7.11390690883921e-05	1
MAPK9|JNK2	3.75338139735e-09	0.281382686195409	1.776600528079e-08	1
PDK1|PDK1_PS241	5.42015042759455e-11	0.275694943457023	4.05084926693909e-10	1
TSC2|TUBERIN	3.97495501769967e-07	0.259696322095843	1.31265956398454e-06	1
YAP1|YAP_PS127	0.000148674266946449	0.259271720746141	0.000335107077879298	1
CLDN7|CLAUDIN-7	0.0235088261067221	0.245326524232987	0.0364563023965522	1
MAPK8|JNK_PT183_PT185	0.000120101552831547	0.235728823934049	0.000279580663968519	1
ATM|ATM	0.000356434909439642	0.232804715071237	0.000755429211051182	1
RPS6KA1|P90RSK_PT359_S363	1.71355441590967e-06	0.229217746034799	4.96581075630966e-06	1
MAP2K1|MEK1_PS217_S221	3.58190021879105e-10	0.229012497776819	2.1192909627847e-09	1
BRAF|B-RAF	0.00153675535301519	0.228101940202204	0.00307351070603038	1
PRKAA1|AMPK_PT172	0.0167654461976257	0.202504161203593	0.0264521484451428	1
MAPK14|P38_PT180_Y182	0.00403029838255839	0.198486989095406	0.00763069827097722	1
FRAP1|MTOR_PS2448	3.25645256631852e-05	0.194327570941578	8.10235371507264e-05	1
DVL3|DVL3	3.22503744965749e-08	0.184856143547047	1.20514557329306e-07	1
CTNNA1|ALPHA-CATENIN	1.48367230161714e-06	0.175241381415343	4.38919722561737e-06	1
RAD50|RAD50	8.94895963664369e-07	0.167056210628917	2.76250493131175e-06	1
PTEN|PTEN	0.00520936185169464	0.165739979763847	0.00973328135448209	1
AKT1 AKT2 AKT3|AKT	0.0080742425074874	0.160465526845238	0.0146992620008104	1
BCL2L11|BIM	0.0145931867973964	0.155442307158116	0.0243792061791799	1
RBM3|RBM3	0.0167548000479707	0.151444653120129	0.0264521484451428	1
PARK7|DJ-1	0.00348039477524115	0.151045895324475	0.00677008298745539	1
IRS1|IRS1	0.001022627395969	0.14050108605854	0.00210453753953041	1
STK11|LBK1	2.99307915853025e-08	0.123374191083893	1.14869524462512e-07	1
XRCC5|KU80	0.0112534280771847	0.113276494428182	0.0194876437434174	1
PRKAA1|AMPK_ALPHA	0.0162648899807969	0.106437823017724	0.0264521484451428	1
AKT1S1|PRAS40_PT246	0.0116987895486658	0.102098123334468	0.0200147965772355	1
YBX1|YB-1_PS102	0.02991287009638	0.1004652001965	0.0442461203508954	1
GSK3A GSK3B|GSK3-ALPHA-BETA	0.0249434177738767	0.0996399782810545	0.0376804821690478	1
MAPK14|P38_MAPK	0.0237809404689953	0.0872305993532625	0.0364563023965522	1
ARAF|A-RAF_PS299	0.0363658264856434	0.0770859662254713	0.0526933404179731	1
BECN1|BECLIN	0.0238763107245025	0.0655265380500279	0.0364563023965522	1
RAF1|C-RAF	0.0373712174461927	0.0560639105358762	0.0530671287735936	1
RAF1|C-RAF_PS338	0.0134049420636937	-0.0592019949961995	0.022660735393387	1
BCL2L1|BCL-XL	0.00855991866728313	-0.0598166884481469	0.0153479035783986	1
CHEK1|CHK1_PS345	0.00864670624135135	-0.0670929516025519	0.0153479035783986	1
EEF2|EEF2	0.00695350797207766	-0.074331092810978	0.0128233523640913	1
TGM2|TRANSGLUTAMINASE	0.0332387156394636	-0.0755325209648734	0.0486587383588024	1
EIF4E|EIF4E	0.00891593922898586	-0.0846060113033343	0.0156304119816789	1
ANLN|ANLN	0.000166461525829329	-0.0897084711248916	0.000369336510433824	1
RPS6KB1|P70S6K_PT389	0.0163087074397341	-0.0988613065218296	0.0264521484451428	1
MET|C-MET_PY1235	0.000612111180286743	-0.100278397692517	0.00127823217059879	1
YWHAE|14-3-3_EPSILON	1.99824916226819e-05	-0.110906592686204	5.25465520448302e-05	1
TP53|P53	0.0291863561209161	-0.112576886645099	0.0436259217807378	1
MAP2K1|MEK1	0.0164207605697227	-0.115740426179371	0.0264521484451428	1
PRKCA |PKC-ALPHA	3.30941208080432e-05	-0.119858390555609	8.10235371507264e-05	1
CDKN1B|P27_PT198	3.95833658716848e-05	-0.12135691712594	9.52684398945634e-05	1
SMAD4|SMAD4	1.55730081593904e-09	-0.135724660685364	7.62540399528771e-09	1
PRDX1|PRDX1	0.000300950821786197	-0.138060053555395	0.000647500252933939	1
ERRFI1|MIG-6	5.9814684365179e-11	-0.140950783432635	4.24684258992771e-10	1
FOXO3|FOXO3A	6.2513095468915e-06	-0.144947057280002	1.67487916161999e-05	1
CHEK1|CHK1	4.75268724200515e-11	-0.146731378478885	3.74934215758184e-10	1
EIF4EBP1|4E-BP1_PT70	3.56009836444888e-07	-0.150614663233694	1.20365230417081e-06	1
EIF4EBP1|4E-BP1_PS65	1.13007264440312e-08	-0.172905706733929	4.86273683349221e-08	1
ERBB3|HER3_PY1289	9.15970668075849e-08	-0.174217164214036	3.33507268889155e-07	1
EGFR|EGFR_PY1173	1.30286755360097e-11	-0.180503848939999	1.23338128407558e-10	1
KRAS|K-RAS	9.74568181418981e-11	-0.185757512624248	6.58993722673787e-10	1
BAK1|BAK	1.05549660792646e-08	-0.188211979289016	4.70532752201707e-08	1
CDC2|CDK1	7.15869438223633e-07	-0.189707287194363	2.25896578283902e-06	1
STMN1|STATHMIN	5.65950738294462e-10	-0.195830262905134	3.09096172453129e-09	1
BID|BID	4.09028029867549e-11	-0.199301405450933	3.41658707301129e-10	1
NOTCH1|NOTCH1	2.01557352768393e-14	-0.214288651764738	3.18012712145687e-13	1
PCNA|PCNA	3.10578567174932e-11	-0.216189759522738	2.75638478367752e-10	1
CDH2|N-CADHERIN	7.57038038947475e-13	-0.229251679619808	8.95828346087846e-12	1
SYK|SYK	0.00363212846633701	-0.230634127786562	0.00696976002999805	1
SRC|SRC	1.08431381694945e-09	-0.257541834446949	5.70268748173414e-09	1
CAV1|CAVEOLIN-1	0.0369731106188756	-0.264702429015433	0.0530321384634377	1
SERPINE1|PAI-1	0.00112110361923529	-0.267618985402976	0.00227423877044873	1
EIF4EBP1|4E-BP1	2.85926867311337e-05	-0.273615887394453	7.2502884211089e-05	1
CCND1|CYCLIN_D1	5.9050367587326e-06	-0.290289776336189	1.61252926873083e-05	1
ERBB2|HER2_PY1248	9.82720817323464e-07	-0.320078452827623	2.96907140553047e-06	1
ANXA1|ANNEXIN_I	0.000237926090058668	-0.338188075679599	0.000519776996743552	1
EGFR|EGFR_PY1068	2.51865572982039e-07	-0.341734242154904	8.72314911303647e-07	1
EGFR|EGFR	3.46362634196237e-23	-0.368292254704538	2.45917470279328e-21	1
CDH3|P-CADHERIN	9.38725606838709e-22	-0.369856256463122	3.33247590427742e-20	1
CCNE1|CYCLIN_E1	1.70039068417052e-15	-0.386214148412638	3.44936395931734e-14	1
LCK|LCK	4.16642518163229e-10	-0.433761471440604	2.36652950316714e-09	1
COL6A1|COLLAGEN_VI	0.00265518044535353	-0.438121736459534	0.00523660587833613	1
KIT|C-KIT	1.06035549791934e-08	-0.469661721289565	4.70532752201707e-08	1
ASNS|ASNS	4.76635002829542e-21	-0.542398810317621	1.3536434080359e-19	1
CCNB1|CYCLIN_B1	5.11360044598576e-06	-0.549383778853065	1.42378679084309e-05	1
CASP7|CASPASE-7_CLEAVEDD198	2.64380614285058e-15	-0.580581622999136	4.69275590355978e-14	1
HSPA1A|HSP70	1.63569133090003e-07	-0.654074884122088	5.80670422469511e-07	1
CAV1|CAVEOLIN-1	2.80715656009114e-36	2.01745622230945	3.98616231532942e-34	2
COL6A1|COLLAGEN_VI	4.99755678313267e-27	1.82885502385963	3.5482653160242e-25	2
HSPA1A|HSP70	3.43172532350696e-10	0.922330997611656	1.57195159979996e-09	2
ANXA1|ANNEXIN_I	5.15616779286331e-20	0.68540085703624	1.04596546655227e-18	2
CCND1|CYCLIN_D1	3.38833628901595e-16	0.51309643499435	3.52848472777912e-15	2
KIT|C-KIT	7.46174091567925e-09	0.507424032844659	2.64891802506613e-08	2
SRC|SRC_PY527	3.63239866766483e-12	0.444322306543427	2.2426113513409e-11	2
FN1|FIBRONECTIN	0.00325431786101422	0.397535986286446	0.00491609719429808	2
BCL2|BCL-2	0.000237137971656475	0.364080799480019	0.000420919899690243	2
BAK1|BAK	4.23065338368529e-17	0.362909374939739	5.46138891348465e-16	2
EGFR|EGFR_PY1173	7.32186538740652e-14	0.356485010666531	5.47213097374593e-13	2
MAPK1 MAPK3|MAPK_PT202_Y204	0.00820893138976616	0.344186365312431	0.0117744268418868	2
BID|BID	2.88351636205684e-14	0.344072821434224	2.40858425536513e-13	2
CDH2|N-CADHERIN	3.72467408608189e-14	0.34405148625333	2.93835400124238e-13	2
ERBB3|HER3	9.67688051885629e-07	0.319149576116614	2.49839460668653e-06	2
KRAS|K-RAS	2.66939859663195e-11	0.299042109984755	1.30708483007495e-10	2
LCK|LCK	4.01395705732796e-06	0.27902484776425	9.19325648613823e-06	2
YWHAE|14-3-3_EPSILON	2.73284823208458e-17	0.27275466587675	3.8806444895601e-16	2
ERBB3|HER3_PY1289	1.25333707447304e-11	0.266156389783916	7.11895458300687e-11	2
SMAD4|SMAD4	1.00875317739521e-14	0.25866005343377	8.95268444938249e-14	2
YAP1|YAP_PS127	8.82609575075637e-05	0.24187992053577	0.000173603571591492	2
STAT3|STAT3_PY705	1.9766863130251e-06	0.237478932060197	4.67815760749274e-06	2
PARK7|DJ-1	5.86774042200431e-07	0.221252509097807	1.57211158476342e-06	2
MAPK14|P38_PT180_Y182	0.000753472420427291	0.216563472398125	0.00125874216118442	2
PEA15|PEA-15	5.61268721163868e-10	0.213765676778093	2.41515631531119e-09	2
MAPK8|JNK_PT183_PT185	8.92469065223869e-05	0.197431513603661	0.000173603571591492	2
FOXO3|FOXO3A	3.00891257855883e-07	0.193729162112103	8.71970583990518e-07	2
PRKCA |PKC-ALPHA	1.58210753451362e-09	0.19285413136276	6.24053527502595e-09	2
RPS6KB1|P70S6K_PT389	0.000904232716330764	0.182847512865987	0.00145992283396384	2
PRKCA |PKC-ALPHA_PS657	3.88182365105628e-05	0.18029001878281	7.98868055724626e-05	2
CDKN1B|P27	0.000150058836119871	0.176856639289076	0.000276731879597684	2
MAP2K1|MEK1	5.73831758601714e-05	0.17123799213979	0.000116405871030633	2
EGFR|EGFR	0.000101329467956072	0.170925450001976	0.000194443033104895	2
BAX|BAX	0.000904740911188859	0.146249321873837	0.00145992283396384	2
PCNA|PCNA	1.21932249767588e-05	0.140918860147709	2.66375068723038e-05	2
SMAD3|SMAD3	1.03271458720487e-06	0.137918998170263	2.61866913184092e-06	2
SRC|SRC	0.00137483765918362	0.111842232201936	0.00212203203917472	2
STMN1|STATHMIN	0.0493023927635664	0.108076659827969	0.0636449070220584	2
MAPK9|JNK2	0.0296515641034515	0.0875744893032437	0.0401002105018106	2
ERRFI1|MIG-6	0.000232466672080409	0.0855035648540472	0.000417851486524279	2
IRS1|IRS1	0.0259894097886296	0.081140548318108	0.0358300600969457	2
NOTCH1|NOTCH1	0.042307090577994	0.0747573283989406	0.0561458585240668	2
RAD50|RAD50	0.00577422666184588	0.073962494175978	0.00845299160806304	2
BCL2L1|BCL-XL	0.0269704120917391	0.0680588411536224	0.0368249857406438	2
MAP2K1|MEK1_PS217_S221	0.00193565349130956	-0.104786124293694	0.00295551393296728	2
CHEK1|CHK1_PS345	0.0072232766607438	-0.114002284283245	0.0104663804676084	2
PTEN|PTEN	0.0340207223965039	-0.115177001968765	0.0455749300028637	2
EIF4EBP1|4E-BP1_PT70	0.000188273511580703	-0.116520880446093	0.000342754341595639	2
STK11|LBK1	8.23816224972535e-06	-0.121248750097131	1.82784224915781e-05	2
EEF2K|EEF2K	0.0233029527844436	-0.125310631943159	0.0324413656410881	2
MRE11A|MRE11	0.0474168899174418	-0.127346538081019	0.061772462094282	2
EIF4EBP1|4E-BP1_PS65	0.000589013988639106	-0.132074123271252	0.000995714123651822	2
MET|C-MET_PY1235	0.014323281529571	-0.146655361294493	0.0203390597719908	2
CASP7|CASPASE-7_CLEAVEDD198	0.0428484913989084	-0.148617842742991	0.0563378312837499	2
TGM2|TRANSGLUTAMINASE	0.000118294126928006	-0.151349757722413	0.000223970213650358	2
NF2|NF2	1.22125044911773e-06	-0.152682753599442	3.04241339955645e-06	2
ARID1A|ARID1A	5.26308448083345e-10	-0.157290630994242	2.33549373836984e-09	2
YBX1|YB-1	0.000554699714387345	-0.161825965590974	0.00094900433063859	2
PRKCD|PKC-DELTA_PS664	4.73170581517053e-07	-0.162131664751681	1.34380445150843e-06	2
AKT1 AKT2 AKT3|AKT	0.00132856109799065	-0.177770217507665	0.00207313929576563	2
STAT5A|STAT5-ALPHA	0.0158321275751889	-0.182407720587426	0.0222590308482854	2
EIF4EBP1|4E-BP1	0.00412909535224982	-0.18656826460746	0.00617191094757341	2
CDC2|CDK1	0.000124400522991201	-0.190932339928721	0.000232432556115139	2
RPS6KA1|P90RSK_PT359_S363	1.6462550404111e-06	-0.1915758583276	4.03048647824786e-06	2
CDKN1B|P27_PT157	9.50898085137377e-07	-0.193654665427405	2.49839460668653e-06	2
AKT1S1|PRAS40_PT246	1.67245914854282e-09	-0.209620837269015	6.41862700251569e-09	2
TSC2|TUBERIN	3.80490684962462e-05	-0.216095482065755	7.94554077421612e-05	2
RBM3|RBM3	0.000396057216443974	-0.218746723545757	0.00069432252759314	2
ARAF|A-RAF_PS299	2.64218416668251e-11	-0.219731252385035	1.30708483007495e-10	2
CCNE1|CYCLIN_E1	1.88352407865421e-05	-0.220313312802217	4.05243059346815e-05	2
RAF1|C-RAF	7.85446031931283e-10	-0.222177980297631	3.28039225100712e-09	2
EEF2|EEF2	4.37089079926127e-11	-0.229810656105506	2.06888831165033e-10	2
ACACA ACACB|ACC_PS79	0.00467936029296614	-0.231941162701929	0.00692155376667908	2
CDKN1B|P27_PT198	7.31760251615453e-12	-0.233552600630969	4.32958148872476e-11	2
ESR1|ER-ALPHA_PS118	1.4538375186156e-07	-0.259253204593932	4.39244526900883e-07	2
ATM|ATM	7.59810126154999e-05	-0.26011599829621	0.000151962025231	2
BECN1|BECLIN	1.83513888532731e-06	-0.270468119621321	4.41677494434708e-06	2
FRAP1|MTOR_PS2448	3.41742394923945e-08	-0.271174125148288	1.12854465300466e-07	2
KDR|VEGFR2	0.00120326780440786	-0.298156281579009	0.00189848920251018	2
SHC1|SHC_PY317	0.000977057409341866	-0.300519560413647	0.00155890058569152	2
RPS6|S6_PS240_S244	6.79605668625323e-06	-0.307538397553292	1.53180960229835e-05	2
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	2.10856919922204e-05	-0.308148339945653	4.46890785506761e-05	2
ACACA|ACC1	0.000903789919684185	-0.309757947219754	0.00145992283396384	2
DVL3|DVL3	1.90611553160902e-11	-0.313482706443765	1.00571716156587e-10	2
TP53BP1|53BP1	2.6897896350449e-07	-0.321892486565591	7.95729433700783e-07	2
RPS6|S6_PS235_S236	0.000513815954236811	-0.322527057537098	0.000889778847580819	2
CTNNA1|ALPHA-CATENIN	5.87320583829126e-08	-0.360435254509416	1.81303310660295e-07	2
GAB2|GAB2	4.4460410050317e-08	-0.367592633207026	1.4348586879875e-07	2
NFKB1|NF-KB-P65_PS536	1.71737865475012e-08	-0.404848061519885	5.94799436523212e-08	2
XRCC5|KU80	3.47878775978223e-16	-0.410105830403479	3.52848472777912e-15	2
SYK|SYK	2.26868073962658e-06	-0.410719223031066	5.2811912299504e-06	2
CHEK2|CHK2	1.46431558792893e-13	-0.419511524898874	9.901562546948e-13	2
RPS6KB1|P70S6K	5.62580318140401e-08	-0.425595512418047	1.77525344835415e-07	2
SRC|SRC_PY416	5.10403591295121e-09	-0.445391449195209	1.85839256317711e-08	2
ERBB2|HER2	5.30538396860771e-07	-0.463074617291226	1.47718534027901e-06	2
GSK3A GSK3B|GSK3-ALPHA-BETA	8.37105068830521e-14	-0.465608317970007	5.9434459886967e-13	2
CTNNB1|BETA-CATENIN	1.91227911001962e-11	-0.497655176607526	1.00571716156587e-10	2
RB1|RB_PS807_S811	8.27164746131273e-13	-0.536711836947524	5.33897245230185e-12	2
PECAM1|CD31	5.48377773492762e-07	-0.542439183957047	1.49749315069177e-06	2
CHEK2|CHK2_PT68	4.4564023511438e-09	-0.575172043418468	1.66528719437479e-08	2
FRAP1|MTOR	1.11335580222507e-19	-0.586894254296773	1.9762065489495e-18	2
ASNS|ASNS	2.33930772790351e-21	-0.595721964852281	6.64363394724597e-20	2
BRAF|B-RAF	3.16248208611319e-20	-0.603903491786802	7.48454093713455e-19	2
RPS6|S6	6.20090464554552e-22	-0.621595869228526	2.93509486555821e-20	2
TP53|P53	1.02550019142771e-09	-0.643887791378463	4.16060077664957e-09	2
CDH1|E-CADHERIN	2.53676755307984e-08	-0.712054175464872	8.57669029850803e-08	2
CLDN7|CLAUDIN-7	3.32388105059763e-16	-0.73963174154899	3.52848472777912e-15	2
CCNB1|CYCLIN_B1	8.80199616300618e-22	-1.0720520566427	3.12470863786719e-20	2
PDCD4|PDCD4	4.62187759071525e-15	-1.48088029602068	4.37537745254377e-14	2
SCD1|SCD1	1.72968947688166e-17	-2.2540559774291	2.72906561907995e-16	2
CCNB1|CYCLIN_B1	7.25139906044363e-17	1.03864491941121	1.14410962953666e-15	3
ASNS|ASNS	7.15356052506969e-16	0.793712219213342	9.23459631418087e-15	3
SCD1|SCD1	5.91793503889383e-09	0.761730977725732	2.5465053803725e-08	3
CASP7|CASPASE-7_CLEAVEDD198	6.61924405951209e-08	0.736952338442408	2.34983164112679e-07	3
PDCD4|PDCD4	1.80233169017635e-06	0.665402576977011	5.38944657555395e-06	3
CCNE1|CYCLIN_E1	3.68338557942504e-14	0.662630542516603	3.48693834852237e-13	3
SYK|SYK	4.87989228532012e-12	0.656774323320252	3.64707739218662e-11	3
KIT|C-KIT	1.28936202153941e-05	0.614078762153934	3.32889831015629e-05	3
TP53|P53	1.13206000266059e-14	0.528865244472755	1.3396043364817e-13	3
CHEK2|CHK2_PT68	1.07737650642253e-24	0.487913677878379	2.18553519874285e-23	3
CDH3|P-CADHERIN	5.64126619980404e-12	0.483661889740371	4.00529900186087e-11	3
EGFR|EGFR	6.38950755199701e-06	0.407658204778252	1.74482706227611e-05	3
RPS6|S6	1.46818810658152e-11	0.379578773876285	9.60458234289221e-11	3
RPS6|S6_PS235_S236	0.000320528045451897	0.370524685363626	0.000679328096330886	3
CHEK2|CHK2	2.75745277554264e-09	0.366553543459829	1.22361966914705e-08	3
AKT1 AKT2 AKT3|AKT_PT308	0.000883865512086321	0.334687395364589	0.00179298432451797	3
SERPINE1|PAI-1	0.0060236438796772	0.334247658889678	0.0100630285989901	3
SRC|SRC_PY416	4.53170149935758e-11	0.325716566399999	2.38333930706954e-10	3
AKT1 AKT2 AKT3|AKT_PS473	0.00982846796285307	0.319799670536421	0.0156813758508442	3
LCK|LCK	5.64410297526649e-05	0.319439948349516	0.000131387315161941	3
EIF4EBP1|4E-BP1_PT37	5.84140731950172e-05	0.314994650425787	0.000133787070866007	3
PECAM1|CD31	9.71223762711889e-11	0.303753932022456	4.92549193946744e-10	3
ANXA1|ANNEXIN_I	0.00216086087705975	0.293074984694921	0.00388407904484158	3
CDC2|CDK1	1.66440130876758e-14	0.29200066561162	1.6881784703214e-13	3
GAB2|GAB2	0.00640553646923117	0.289122805489091	0.0105765834724515	3
CDKN1B|P27_PT198	2.2534447888938e-11	0.253133581810075	1.27995664009168e-10	3
RPS6|S6_PS240_S244	0.00182036647933142	0.242898863709529	0.00340248725115611	3
NFKB1|NF-KB-P65_PS536	0.00470360245011233	0.237929322911379	0.00804712708332471	3
EIF4EBP1|4E-BP1_PS65	1.85840549306866e-11	0.234964259752367	1.13462876157428e-10	3
EIF4EBP1|4E-BP1	0.00178378850042009	0.231258670929915	0.00340248725115611	3
YBX1|YB-1_PS102	2.17817516566832e-05	0.227033969431634	5.24238768686274e-05	3
NOTCH1|NOTCH1	3.26173880209378e-07	0.209396558943423	1.10277835689837e-06	3
AKT1S1|PRAS40_PT246	1.15871730002235e-09	0.206169147325234	5.48459522010579e-09	3
MYC|C-MYC	1.16737942588923e-05	0.19183172587385	3.12769582030699e-05	3
TGM2|TRANSGLUTAMINASE	6.03934606103261e-06	0.188095169986884	1.68154341307182e-05	3
MET|C-MET_PY1235	1.55518099358877e-09	0.185759092493213	7.12373229321308e-09	3
CHEK1|CHK1_PS345	1.91768241392836e-11	0.174270368300144	1.13462876157428e-10	3
CHEK1|CHK1	1.82178475793373e-06	0.16094437261053	5.38944657555395e-06	3
CDKN1B|P27_PT157	2.92653135407808e-13	0.159530449298017	2.5972965767443e-12	3
XRCC5|KU80	0.0117269713491584	0.155187403460116	0.0185025547953388	3
MRE11A|MRE11	1.56551159872296e-05	0.154431433500449	3.90004643892387e-05	3
STMN1|STATHMIN	6.34103672592915e-05	0.145310204648519	0.000142924954774911	3
EIF4EBP1|4E-BP1_PT70	5.3656071540238e-06	0.144157047631022	1.52383243174276e-05	3
ANLN|ANLN	4.44466434818336e-07	0.137906571496931	1.46777287777218e-06	3
DVL3|DVL3	0.000978390135961625	0.135542378380379	0.00195678027192325	3
EEF2|EEF2	1.08575401799837e-06	0.131888733800512	3.35167544686453e-06	3
BECN1|BECLIN	6.90183416299771e-05	0.120134158180738	0.000153134445491512	3
YBX1|YB-1	0.00324262000873397	0.119704781325068	0.0057556505155028	3
SRC|SRC	0.00214387695485881	0.116088866784365	0.00388407904484158	3
PRKCA |PKC-ALPHA	0.00717687719018072	0.0940986458135795	0.0117139834598352	3
ERRFI1|MIG-6	0.00414594305467035	0.0904948957565007	0.00717955992394134	3
NF2|NF2	0.024554203902984	0.071282072148829	0.0370925207896141	3
ARID1A|ARID1A	0.0421786674253496	0.0689581076796368	0.0623892788999963	3
RAF1|C-RAF_PS338	0.0201880375373645	0.0660963875191799	0.0308247454871587	3
BCL2L1|BCL-XL	0.00172503566866664	-0.063468101205474	0.00335554883494059	3
PIK3CA |PI3K-P110-ALPHA	0.019255407230892	-0.0703601854502582	0.0297203024650724	3
YWHAE|14-3-3_EPSILON	0.0035914914575297	-0.0760251181237223	0.00629619490085454	3
ERBB3|HER3_PY1289	0.000124782392151436	-0.129025013830286	0.000272601533623137	3
RAD50|RAD50	3.51060432919563e-05	-0.132254743686796	8.30843024576299e-05	3
ERBB3|HER3	0.0137065311492904	-0.135343738042078	0.0213882134417499	3
PRKAA1|AMPK_ALPHA	1.19283981314927e-07	-0.15068357908744	4.13129886505357e-07	3
PEA15|PEA-15	1.46123093196751e-05	-0.154432029235319	3.70526414891761e-05	3
RPS6KB1|P70S6K	0.0097634746934167	-0.161806147407895	0.0156813758508442	3
MAPK14|P38_MAPK	4.8766408254112e-06	-0.170969202934448	1.41323060654774e-05	3
CDKN1B|P27	0.00198531395025387	-0.177816910001989	0.0036612283238448	3
IRS1|IRS1	8.16181890177785e-07	-0.184630749463883	2.63404155466467e-06	3
AKT1 AKT2 AKT3|AKT	0.00595967708740239	-0.18491174951866	0.0100630285989901	3
TSC2|TUBERIN	0.00151162294178644	-0.187837867955021	0.00298125635741215	3
SMAD3|SMAD3	2.61450212446899e-11	-0.193745220614768	1.42792039105614e-10	3
PTEN|PTEN	0.00182104951470327	-0.203833103310957	0.00340248725115611	3
RBM3|RBM3	0.000365496300629622	-0.228315141812871	0.000763242274844211	3
MAPK8|JNK_PT183_PT185	6.60658597949294e-08	-0.240476274027308	2.34983164112679e-07	3
TP53BP1|53BP1	0.000192680809975105	-0.251633966932139	0.00041455568206765	3
PRKAA1|AMPK_PT172	0.000715940369483843	-0.262294795126971	0.00147338452850298	3
PDK1|PDK1_PS241	1.2370287487803e-12	-0.308506668561408	1.03328283721649e-11	3
BCL2L11|BIM	1.80456823824203e-08	-0.334900785199136	6.92564026568563e-08	3
MAPK1 MAPK3|MAPK_PT202_Y204	0.0279103357777392	-0.337850372644094	0.0417186071625154	3
ACACA ACACB|ACC_PS79	2.09884598821666e-05	-0.346988204630209	5.13855397115113e-05	3
ERBB2|HER2_PY1248	9.62514463978668e-07	-0.362002104044038	3.03726786411046e-06	3
EEF2K|EEF2K	1.27310313078984e-10	-0.367121656822224	6.23381533007439e-10	3
KDR|VEGFR2	1.21168963955122e-05	-0.378303660289899	3.18629497807913e-05	3
PARK7|DJ-1	1.48803388411006e-11	-0.379760508575521	9.60458234289221e-11	3
MAPK9|JNK2	5.38221060231386e-23	-0.428096912372592	9.5534238191071e-22	3
CCND1|CYCLIN_D1	1.36608930798827e-14	-0.487534152933177	1.49218985949488e-13	3
ESR1|ER-ALPHA_PS118	1.01200061668255e-31	-0.505806647453268	2.3950681261487e-30	3
ACACA|ACC1	1.71810296001316e-08	-0.530102104984205	6.77696167560746e-08	3
ERBB2|HER2	1.43354211945609e-08	-0.563672139576083	5.81608517036471e-08	3
COL6A1|COLLAGEN_VI	9.00637443103624e-09	-0.691153189833631	3.76148579178572e-08	3
IGFBP2|IGFBP2	5.72257226511716e-08	-0.818447691077758	2.1384348990701e-07	3
INPP4B|INPP4B	3.24956531435928e-33	-0.826193483492208	9.22876549278035e-32	3
BCL2|BCL-2	2.25390707348177e-12	-0.967578172331968	1.77808224685784e-11	3
CAV1|CAVEOLIN-1	5.1697843448952e-16	-1.16970130040077	7.34109376975118e-15	3
AR|AR	6.07064253187187e-34	-1.37754576324036	2.15507809881451e-32	3
GATA3|GATA3	4.26531297836654e-44	-1.83009845003517	2.01891480976016e-42	3
PGR|PR	1.72818983240669e-51	-2.60931962572204	1.22701478100875e-49	3
ESR1|ER-ALPHA	5.35974865568172e-74	-3.90377003368168	7.61084309106804e-72	3
ESR1|ER-ALPHA	1.96972999073665e-23	2.22335973044941	2.79701658684604e-21	4
GATA3|GATA3	1.29569316571556e-18	1.10086610629055	9.19942147658048e-17	4
SCD1|SCD1	8.124802187113e-14	1.0646580102054	2.30744382114009e-12	4
CLDN7|CLAUDIN-7	7.33280924084181e-11	0.779139804787723	1.48751273171362e-09	4
ACACA|ACC1	4.53287829214737e-09	0.649877420236866	5.36390597904106e-08	4
IGFBP2|IGFBP2	3.22152933387756e-05	0.584526023222186	0.000114364291352653	4
AR|AR	6.8072001568977e-07	0.500552737196741	4.02759342616447e-06	4
BRAF|B-RAF	3.75738540541363e-08	0.460932436951646	3.3346795473046e-07	4
RPS6KB1|P70S6K	7.69340069638565e-08	0.458620444388955	6.06923832714868e-07	4
BCL2|BCL-2	0.000948719599084607	0.4364867172422	0.00236347689596516	4
FRAP1|MTOR	2.62000396293391e-07	0.370713479272156	1.77162172731722e-06	4
INPP4B|INPP4B	2.39327713180719e-05	0.361098704854839	8.94329875570055e-05	4
BCL2L11|BIM	8.37058426785003e-07	0.35247178165572	4.57162679244117e-06	4
ACACA ACACB|ACC_PS79	0.000698383524422785	0.344539844929102	0.00177090107978635	4
ESR1|ER-ALPHA_PS118	4.26002621561277e-08	0.342405762116678	3.55837483892361e-07	4
CDH1|E-CADHERIN	0.0202714859697862	0.334204092372904	0.0346813374422848	4
CCNB1|CYCLIN_B1	0.00308261614174907	0.324378500588848	0.00653330585266221	4
RBM3|RBM3	1.38201662626736e-06	0.300889670930938	7.26838373814686e-06	4
KDR|VEGFR2	0.00173858470755638	0.298738694569947	0.0041146504745501	4
TP53BP1|53BP1	0.00280265325141672	0.2281859776034	0.00617482769199932	4
GSK3A GSK3B|GSK3-ALPHA-BETA	2.05967851806611e-05	0.228104656162347	7.90471215041588e-05	4
CCND1|CYCLIN_D1	0.00342978148998274	0.216267459126322	0.00705839089242825	4
RPS6|S6	3.43416424438739e-05	0.208082788004011	0.000118939347000734	4
PECAM1|CD31	9.04921801581366e-05	0.206074342593345	0.000279345425705552	4
EIF4EBP1|4E-BP1	0.0133527472154392	0.198582476921238	0.0246245468128879	4
PRDX1|PRDX1	0.000110178596443033	0.180195513447189	0.000325945014477306	4
EEF2K|EEF2K	0.000339055585127253	0.178618616215781	0.000908413077133395	4
CTNNA1|ALPHA-CATENIN	5.11045732310017e-05	0.164760336824075	0.000168763939507029	4
RAF1|C-RAF	2.3872677133122e-06	0.164601416714316	1.16893798375977e-05	4
ASNS|ASNS	0.0210782413796542	0.163370789420981	0.0356322651894154	4
TSC2|TUBERIN	0.00282650563366166	0.146570049161098	0.00617482769199932	4
XRCC5|KU80	0.00202549132301005	0.140196576391699	0.0047150781617611	4
FRAP1|MTOR_PS2448	0.00830663766638656	0.134471185754647	0.016158117104478	4
SMAD3|SMAD3	5.64870815931065e-05	0.124984481700183	0.000182299217868662	4
PDK1|PDK1_PS241	0.0010250576296185	0.11965227657805	0.0025096238518246	4
TP53|P53	0.028457401386911	0.118395007873047	0.047540599964016	4
CHEK2|CHK2	0.0167295441854997	0.115748733955883	0.0293283367202587	4
CHEK2|CHK2_PT68	0.0333523676018997	0.114663898239883	0.0550701883659274	4
EEF2|EEF2	0.000197926860711422	0.109043527209042	0.000562112284420438	4
MAPK9|JNK2	0.0139558029251656	0.103405334364533	0.0253701885819642	4
XRCC1|XRCC1	1.56326986911803e-05	0.100447067465644	6.16623115041001e-05	4
BECN1|BECLIN	0.00104735815259807	0.0953204427562632	0.00252076029947332	4
PIK3CA |PI3K-P110-ALPHA	0.000599471038267538	0.0890057417480314	0.00154772522607255	4
ARID1A|ARID1A	0.014114400689966	0.0778845197741701	0.0253701885819642	4
PRKCD|PKC-DELTA_PS664	0.000322198091750381	0.077485961545683	0.000879848635164502	4
STK11|LBK1	0.00827794313075004	0.0573915300164214	0.016158117104478	4
BCL2L1|BCL-XL	0.017153684804814	0.0542241342493011	0.0297051614912633	4
RAF1|C-RAF_PS338	0.0155508373180575	-0.0549655046811395	0.0276027362395521	4
YWHAE|14-3-3_EPSILON	0.00506434606987277	-0.0696633386889903	0.0101286921397455	4
SMAD4|SMAD4	0.0085535909796439	-0.0811363390378193	0.0164136475555329	4
AKT1S1|PRAS40_PT246	0.0123178306565302	-0.0820604512116423	0.0230148941214117	4
CHEK1|CHK1	3.89644051153863e-05	-0.0902597233610709	0.000131736798247258	4
STMN1|STATHMIN	0.00252179481648931	-0.0958071906292255	0.00577572361195939	4
MYC|C-MYC	0.00298890404468913	-0.101287377932044	0.00643067233857358	4
MAP2K1|MEK1_PS217_S221	0.0026046948961407	-0.102683549704928	0.00587089960717428	4
FOXO3|FOXO3A	0.00335893573842243	-0.113444349345292	0.00701424815964684	4
ERBB3|HER3	0.00987396700829935	-0.12080004076974	0.0186947108690468	4
KRAS|K-RAS	8.42605730245554e-06	-0.121997231025547	3.6257579907536e-05	4
CDH2|N-CADHERIN	1.50466700789259e-05	-0.132061349301815	6.10464900344994e-05	4
NOTCH1|NOTCH1	6.73559001863257e-07	-0.135010542120388	4.02759342616447e-06	4
BID|BID	2.34383992919772e-07	-0.147132980180696	1.66412634973038e-06	4
MAPK8|JNK_PT183_PT185	0.00355307897835883	-0.149535974737664	0.00720767449895648	4
STAT3|STAT3_PY705	0.000100326744596578	-0.14977729712386	0.000303114845376895	4
BAK1|BAK	1.9783373276566e-07	-0.152236878500723	1.4785468448802e-06	4
EGFR|EGFR_PY1173	7.38592119615656e-09	-0.155167012921492	8.06769853734024e-08	4
ERBB3|HER3_PY1289	4.90277148676364e-06	-0.155427451170867	2.17560484725137e-05	4
PRKCA |PKC-ALPHA	6.63265563471153e-14	-0.177027244511288	2.30744382114009e-12	4
CDH3|P-CADHERIN	2.83880090154065e-06	-0.203409244520915	1.34369909339591e-05	4
PRKCA |PKC-ALPHA_PS657	2.16407420726348e-06	-0.226723214471438	1.09749477654076e-05	4
ERBB2|HER2_PY1248	0.000401741830011493	-0.227798348317424	0.00105643221965985	4
LCK|LCK	0.000120709806195514	-0.239159705716418	0.000349812091423734	4
YBX1|YB-1_PS102	2.87958699148313e-08	-0.25808854285859	2.72600901860403e-07	4
EGFR|EGFR	2.58236988041605e-11	-0.262887913158817	6.11160871698465e-10	4
SRC|SRC_PY527	1.08246163773563e-05	-0.322792380613079	4.52086919289587e-05	4
EGFR|EGFR_PY1068	4.466692534879e-09	-0.377328437684216	5.36390597904106e-08	4
MAPK14|P38_PT180_Y182	4.90855277080625e-07	-0.386022271368538	3.1682476975204e-06	4
AKT1 AKT2 AKT3|AKT_PT308	1.95972072136534e-08	-0.4015103297637	1.98771673167056e-07	4
YAP1|YAP_PS127	2.29684400241196e-09	-0.439329499262059	3.45499343567111e-08	4
CAV1|CAVEOLIN-1	0.00031747631601605	-0.459286491591316	0.000879848635164502	4
HSPA1A|HSP70	2.55674998960758e-05	-0.488557966289038	9.30919226985324e-05	4
KIT|C-KIT	3.126447118143e-10	-0.509025491652618	5.54944363470383e-09	4
AKT1 AKT2 AKT3|AKT_PS473	2.43309396878247e-09	-0.580224529743528	3.45499343567111e-08	4
FN1|FIBRONECTIN	5.96005667391292e-05	-0.590573800331219	0.000188072899487919	4
COL6A1|COLLAGEN_VI	8.00863990429858e-07	-0.623654790235058	4.54890746564159e-06	4
MAPK1 MAPK3|MAPK_PT202_Y204	3.06814491976982e-06	-0.672599603691683	1.40540831808811e-05	4
ANXA1|ANNEXIN_I	1.644698376655e-16	-0.696229815869681	7.78490564950033e-15	4
ERBB2|HER2	2.0250960407041e-16	2.94982054525892	2.87563637779982e-14	5
ERBB2|HER2_PY1248	2.2755217082564e-13	2.26369942288503	1.07708027524136e-11	5
EGFR|EGFR_PY1068	6.21172857696528e-08	1.69510207185916	1.10258182241134e-06	5
SCD1|SCD1	5.14312865313841e-08	1.08839870307026	1.04332038392236e-06	5
CCNB1|CYCLIN_B1	0.000133243047832722	0.552892147100937	0.000900976799630787	5
ACACA|ACC1	0.010019586498579	0.483047724156875	0.0309300278869178	5
RPS6KB1|P70S6K	0.00994899681121522	0.475896985847813	0.0309300278869178	5
ACACA ACACB|ACC_PS79	0.0284131515015436	0.410410090411748	0.0720476341646284	5
SHC1|SHC_PY317	0.000151442505532398	0.390064344019639	0.000977492535709114	5
RPS6|S6_PS240_S244	0.00223392994604035	0.34316282520216	0.00940208027206905	5
ERBB3|HER3_PY1289	0.00101685377727945	0.339701317635121	0.00497907711633386	5
RB1|RB_PS807_S811	0.00249078959693492	0.33837790226038	0.0101054892218502	5
TP53|P53	0.000427340519960134	0.331830611936319	0.002247494586457	5
NFKB1|NF-KB-P65_PS536	0.0014883259498238	0.331382832650703	0.00660444640234311	5
RPS6|S6_PS235_S236	0.00436834722744633	0.331033575955189	0.0155076326574345	5
AKT1 AKT2 AKT3|AKT	0.000324636155212234	0.309956737043527	0.00192076391833905	5
ASNS|ASNS	0.0167896318846413	0.294544800422437	0.0467476025023346	5
SRC|SRC_PY416	0.000592270950175565	0.251576279092207	0.00300365981874751	5
PTEN|PTEN	0.0001034373986966	0.209924373775511	0.00073440553074586	5
CDKN1B|P27_PT198	0.000355943210134087	0.195468174608887	0.00201057696024874	5
GSK3A GSK3B|GSK3-ALPHA-BETA	0.00359480813316287	0.194119540424004	0.0134332303923455	5
PECAM1|CD31	0.000248910141249944	0.187116343074982	0.00153674956771705	5
ARAF|A-RAF_PS299	0.0147558373183425	0.186087349076443	0.0427618142694823	5
CHEK2|CHK2_PT68	0.00837292236178822	0.183044236486963	0.0276501157063704	5
RPS6|S6	0.0029716597084629	0.174793256322467	0.0114047480703171	5
PXN|PAXILLIN	0.0133219476672945	0.172733858290409	0.0394107618490796	5
EIF4EBP1|4E-BP1_PS65	0.00147668028230549	0.156814659667056	0.00660444640234311	5
EEF2|EEF2	8.29683186632719e-05	0.149012294310124	0.000689921118476798	5
CDC2|CDK1	0.00882989546926047	0.126264827194931	0.0284964808326133	5
PRKCD|PKC-DELTA_PS664	0.00225120231866442	0.115324910559218	0.00940208027206905	5
DVL3|DVL3	0.023717389332645	0.0994002289048346	0.062367949726585	5
EIF4EBP1|4E-BP1_PT70	0.0274745735645845	0.0788519980268827	0.0709343535667454	5
STK11|LBK1	0.0113684750474158	-0.0505351333153957	0.0343473075900648	5
BAK1|BAK	0.00688867681500201	-0.090526558798603	0.0232902882792925	5
ERRFI1|MIG-6	0.00401068469324906	-0.0986747858892361	0.0146030058061889	5
EGFR|EGFR_PY1173	0.00583187324689268	-0.0999265952187349	0.0201981951477746	5
SRC|SRC	0.0434102694631606	-0.110535614930118	0.10273763772948	5
BAX|BAX	0.0027560329164349	-0.133746666149545	0.0108710187259377	5
RAD50|RAD50	6.18530819305032e-05	-0.134157598757293	0.000548946102133216	5
IRS1|IRS1	0.000368133809623008	-0.134787627296072	0.00201057696024874	5
YWHAE|14-3-3_EPSILON	9.2313389091966e-05	-0.135869984048836	0.000689921118476798	5
XRCC1|XRCC1	1.60549369359522e-05	-0.136902025256878	0.000164795545699432	5
BRAF|B-RAF	0.0408775123031117	-0.155899908448671	0.0983831652040993	5
SMAD4|SMAD4	9.47237094405048e-07	-0.158815859431743	1.35078219416536e-05	5
CCND1|CYCLIN_D1	0.0198327432863843	-0.165041843172637	0.0534795488516019	5
SMAD3|SMAD3	2.9785218105011e-08	-0.212659064933097	7.0491682848526e-07	5
INPP4B|INPP4B	0.0310035221374522	-0.220770020507153	0.0772368446231265	5
PARK7|DJ-1	0.0013874811435572	-0.224755596963099	0.00656741074617075	5
GAB2|GAB2	0.0199606766840486	-0.245535308403457	0.0534795488516019	5
KDR|VEGFR2	0.0372879453704116	-0.258375425079938	0.0912911765965249	5
CDKN1B|P27	1.62474481675496e-05	-0.299025282272973	0.000164795545699432	5
ESR1|ER-ALPHA_PS118	3.90497938908606e-06	-0.30735341705322	5.04097339318382e-05	5
BCL2L11|BIM	2.19413069560944e-05	-0.347352708445103	0.00020771103918436	5
GATA3|GATA3	0.015813599085528	-0.503644389190355	0.0449106214028995	5
KIT|C-KIT	2.36834385198512e-11	-0.566845761279444	6.72609653963774e-10	5
COL6A1|COLLAGEN_VI	8.82841141426142e-05	-0.676487308595195	0.000689921118476798	5
CAV1|CAVEOLIN-1	5.93433430193108e-06	-0.783040174244965	7.02229559061844e-05	5
BCL2|BCL-2	5.05040566437664e-12	-1.15298060046971	1.79289401085371e-10	5
PGR|PR	4.13305790188937e-16	-2.04644924811617	2.93447111034145e-14	5
ESR1|ER-ALPHA	9.51255066313633e-07	-2.12407145549231	1.35078219416536e-05	5