Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.038 0.148 0.41 24.0 -9999.0 0.0 24.0 KIRREL -0.058 0.189 -9999.0 0.0 -0.469 33.0 33.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.038 0.149 -9999.0 0.0 -0.411 24.0 24.0 PLCG1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.01 0.123 -9999.0 0.0 -0.311 24.0 24.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.023 0.093 -9999.0 0.0 -0.274 21.0 21.0 FYN -0.024 0.131 0.269 12.0 -0.301 24.0 36.0 mol:Ca2+ -0.006 0.116 -9999.0 0.0 -0.302 22.0 22.0 mol:DAG -0.006 0.117 -9999.0 0.0 -0.303 22.0 22.0 NPHS2 -0.011 0.032 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.006 0.117 -9999.0 0.0 -0.303 22.0 22.0 regulation of endocytosis -0.011 0.112 -9999.0 0.0 -0.283 24.0 24.0 Nephrin/NEPH1/podocin/Cholesterol -0.019 0.117 -9999.0 0.0 -0.31 24.0 24.0 establishment of cell polarity -0.038 0.148 -9999.0 0.0 -0.41 24.0 24.0 Nephrin/NEPH1/podocin/NCK1-2 -0.004 0.11 -9999.0 0.0 -0.285 21.0 21.0 Nephrin/NEPH1/beta Arrestin2 -0.01 0.114 -9999.0 0.0 -0.286 24.0 24.0 NPHS1 -0.018 0.068 -9999.0 0.0 -0.256 11.0 11.0 Nephrin/NEPH1/podocin -0.017 0.116 -9999.0 0.0 -0.302 24.0 24.0 TJP1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.02 0.012 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.005 0.118 -9999.0 0.0 -0.304 22.0 22.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.01 0.124 -9999.0 0.0 -0.312 24.0 24.0 GRB2 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.032 0.128 0.283 10.0 -0.291 26.0 36.0 cytoskeleton organization -0.03 0.108 0.2 5.0 -0.309 22.0 27.0 Nephrin/NEPH1 -0.023 0.106 -9999.0 0.0 -0.29 24.0 24.0 Nephrin/NEPH1/ZO-1 -0.015 0.127 -9999.0 0.0 -0.331 24.0 24.0