Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.003 0.084 0.476 12.0 -9999.0 0.0 12.0 KIRREL 0.007 0.045 -9999.0 0.0 -0.444 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.003 0.084 -9999.0 0.0 -0.477 12.0 12.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.002 0.091 -9999.0 0.0 -0.442 11.0 11.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.019 0.051 -9999.0 0.0 -0.482 1.0 1.0 FYN 0.006 0.071 -9999.0 0.0 -0.395 11.0 11.0 mol:Ca2+ 0.01 0.078 -9999.0 0.0 -0.438 11.0 11.0 mol:DAG 0.011 0.079 -9999.0 0.0 -0.44 11.0 11.0 NPHS2 -0.002 0.073 -9999.0 0.0 -0.746 4.0 4.0 mol:IP3 0.011 0.079 -9999.0 0.0 -0.44 11.0 11.0 regulation of endocytosis 0.015 0.067 -9999.0 0.0 -0.368 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol 0.003 0.079 -9999.0 0.0 -0.449 11.0 11.0 establishment of cell polarity 0.003 0.084 -9999.0 0.0 -0.476 12.0 12.0 Nephrin/NEPH1/podocin/NCK1-2 0.018 0.074 -9999.0 0.0 -0.403 11.0 11.0 Nephrin/NEPH1/beta Arrestin2 0.016 0.068 -9999.0 0.0 -0.372 11.0 11.0 NPHS1 -0.003 0.101 -9999.0 0.0 -0.738 8.0 8.0 Nephrin/NEPH1/podocin 0.008 0.071 -9999.0 0.0 -0.398 11.0 11.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.011 0.079 -9999.0 0.0 -0.442 11.0 11.0 CD2AP -0.002 0.08 -9999.0 0.0 -0.441 14.0 14.0 Nephrin/NEPH1/podocin/GRB2 0.011 0.079 -9999.0 0.0 -0.442 11.0 11.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.003 0.09 -9999.0 0.0 -0.409 13.0 13.0 cytoskeleton organization 0.022 0.064 -9999.0 0.0 -0.641 1.0 1.0 Nephrin/NEPH1 0.004 0.062 -9999.0 0.0 -0.346 12.0 12.0 Nephrin/NEPH1/ZO-1 0.012 0.069 -9999.0 0.0 -0.455 8.0 8.0