Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
APC	163 (73%)	60	0.0059899	1	0.00127	0.483	0.14488	1	NA	NA	0.29682	1	0.15425	1	0.75492	1	0.055539	1	0.64308	1	0.83111	1
TP53	117 (52%)	106	0.0025	0.94	0.00091999	0.352	9.9999e-06	0.00401	NA	NA	0.75321	1	0.95455	1	0.01808	1	0.00065999	0.254	0.03296	1	0.2551	1
KRAS	97 (43%)	126	0.00017	0.0671	0.00037	0.145	0.5056	1	0.10725	1	0.56942	1	0.95368	1	0.00023	0.0906	0.0068599	1	0.02273	1	0.13878	1
NRAS	20 (9%)	203	0.04711	1	0.03242	1	0.26859	1	NA	NA	0.91195	1	0.63563	1	0.33174	1	1	1	0.26669	1	0.62637	1
SMAD4	26 (12%)	197	0.02997	1	0.074349	1	0.062509	1	NA	NA	0.85938	1	1	1	0.4155	1	0.01406	1	1	1	0.3657	1
FBXW7	38 (17%)	185	0.060499	1	0.01794	1	0.00045	0.175	NA	NA	0.01125	1	0.11898	1	0.00268	1	0.00101	0.386	0.41506	1	0.01404	1
SMAD2	15 (7%)	208	0.13537	1	0.67709	1	0.43715	1	NA	NA	0.5963	1	0.67792	1	0.56688	1	0.23684	1	1	1	0.73117	1
FAM123B	24 (11%)	199	0.086719	1	0.30402	1	0.02665	1	NA	NA	0.54057	1	1	1	0.074159	1	0.075749	1	1	1	0.061649	1
PIK3CA	33 (15%)	190	0.20346	1	0.40777	1	0.0050299	1	NA	NA	0.061539	1	0.3159	1	0.02763	1	0.02715	1	0.16414	1	0.74798	1
TCF7L2	18 (8%)	205	1	1	0.63422	1	0.20856	1	NA	NA	0.8362	1	0.60639	1	0.33502	1	0.61234	1	1	1	0.12965	1
ARID1A	20 (9%)	203	0.02338	1	0.19306	1	0.01551	1	NA	NA	0.97782	1	0.50873	1	0.91215	1	0.73575	1	1	1	0.0135	1
BRAF	21 (9%)	202	9.9999e-06	0.00401	9.9999e-06	0.00401	5e-05	0.0198	NA	NA	0.39697	1	1	1	0.37173	1	9.9999e-06	0.00401	1	1	0.14788	1
MGC42105	11 (5%)	212	0.00134	0.507	0.058419	1	0.10999	1	NA	NA	0.13389	1	1	1	1	1	0.11325	1	1	1	0.24868	1
ACVR1B	14 (6%)	209	0.37537	1	0.02705	1	0.04389	1	NA	NA	0.73443	1	0.19114	1	1	1	0.18955	1	0.58196	1	0.22907	1
CDC27	13 (6%)	210	0.00026	0.102	0.24973	1	0.00071999	0.276	NA	NA	0.9362	1	0.82579	1	0.44111	1	0.03941	1	0.45921	1	0.00251	0.941
KIAA1804	15 (7%)	208	0.27007	1	0.89366	1	0.087619	1	NA	NA	0.50813	1	0.74965	1	0.56816	1	0.23752	1	1	1	0.20784	1
PCDHGB1	8 (4%)	215	0.20628	1	0.19726	1	0.19004	1	NA	NA	0.50835	1	0.66819	1	0.52577	1	0.45028	1	1	1	0.25041	1
PCBP1	5 (2%)	218	0.56746	1	0.72809	1	0.50353	1	NA	NA	NA	NA	NA	NA	1	1	0.49366	1	1	1	1	1
ZHX2	10 (4%)	213	0.1184	1	0.22195	1	0.38896	1	NA	NA	0.23756	1	0.22201	1	0.56006	1	0.51756	1	1	1	0.20509	1
PCDHA3	12 (5%)	211	0.04434	1	0.00042	0.164	0.088579	1	NA	NA	0.84605	1	1	1	0.5147	1	0.16087	1	1	1	0.36951	1
PCDHA2	12 (5%)	211	0.20721	1	0.78461	1	0.04494	1	NA	NA	0.90571	1	1	1	0.75469	1	0.32343	1	0.52537	1	0.079659	1
ELF3	8 (4%)	215	0.79744	1	0.80137	1	0.090039	1	NA	NA	0.88049	1	0.33897	1	0.022	1	0.12114	1	1	1	0.26172	1
CRTC1	4 (2%)	219	0.064409	1	0.11717	1	0.62847	1	NA	NA	NA	NA	NA	NA	1	1	0.24604	1	1	1	1	1
CASP8	10 (4%)	213	0.00027	0.106	9.9999e-06	0.00401	0.00046	0.178	NA	NA	0.04433	1	0.23118	1	1	1	0.00128	0.485	1	1	0.056369	1
CACNG3	8 (4%)	215	0.01546	1	0.20446	1	0.0069999	1	NA	NA	0.12613	1	0.33406	1	0.14374	1	0.063339	1	0.3858	1	0.02505	1
PCDHGA7	5 (2%)	218	0.3646	1	0.49248	1	0.14418	1	NA	NA	NA	NA	NA	NA	0.74346	1	1	1	1	1	0.6406	1
CCBP2	10 (4%)	213	0.15841	1	0.03777	1	0.56754	1	NA	NA	0.071979	1	1	1	0.37342	1	0.51581	1	1	1	0.37339	1
MAP2K4	11 (5%)	212	0.45809	1	0.44605	1	0.087389	1	NA	NA	0.10018	1	0.52307	1	0.42596	1	0.67485	1	1	1	0.37514	1
PCDHGA9	6 (3%)	217	0.068069	1	0.078589	1	0.01069	1	NA	NA	0.66794	1	0.58895	1	0.37803	1	0.20539	1	1	1	0.73223	1
RBM10	8 (4%)	215	0.27529	1	0.73243	1	0.72569	1	NA	NA	0.23864	1	0.74077	1	1	1	0.1361	1	1	1	1	1
PTEN	7 (3%)	216	0.02689	1	0.39249	1	0.03373	1	NA	NA	0.54226	1	1	1	0.098729	1	0.01644	1	0.34783	1	0.02431	1
DNMT1	17 (8%)	206	0.02439	1	0.065749	1	0.10986	1	NA	NA	0.054139	1	0.3319	1	0.35454	1	0.03648	1	1	1	0.070239	1
BCOR	9 (4%)	214	0.0193	1	0.2813	1	0.0063499	1	NA	NA	0.46568	1	1	1	0.75585	1	0.14407	1	1	1	0.02502	1
PCDHGB5	7 (3%)	216	0.10005	1	0.072579	1	0.24337	1	NA	NA	0.88151	1	0.73879	1	0.069739	1	0.567	1	1	1	1	1
ZFP3	8 (4%)	215	0.00049	0.19	0.057529	1	0.00254	0.95	NA	NA	0.28915	1	0.7368	1	0.2004	1	0.00475	1	1	1	0.0073699	1
RWDD2B	7 (3%)	216	0.02569	1	0.73312	1	0.0335	1	NA	NA	0.86044	1	0.48642	1	1	1	0.30853	1	1	1	0.00050999	0.197
TBC1D10C	3 (1%)	220	0.69313	1	0.23974	1	0.8176	1	NA	NA	NA	NA	NA	NA	1	1	0.61387	1	1	1	0.59658	1
ERCC6L	5 (2%)	218	0.005	1	0.48861	1	0.33389	1	NA	NA	NA	NA	NA	NA	0.7434	1	0.70516	1	1	1	0.18753	1
ERBB3	14 (6%)	209	0.13594	1	0.04233	1	0.11293	1	NA	NA	0.6632	1	0.72716	1	0.84387	1	0.19876	1	1	1	0.053849	1
KLK2	3 (1%)	220	0.53998	1	0.13284	1	0.82003	1	NA	NA	NA	NA	NA	NA	1	1	0.61091	1	NA	NA	NA	NA
TAPBP	5 (2%)	218	0.10088	1	0.64435	1	0.3322	1	NA	NA	1	1	0.17369	1	0.30136	1	0.29113	1	1	1	0.01312	1
ERBB2	9 (4%)	214	0.37789	1	0.18882	1	0.35001	1	NA	NA	0.074349	1	0.28286	1	0.32079	1	0.078869	1	0.38585	1	0.1164	1
MORC2	5 (2%)	218	0.18334	1	0.64157	1	0.33275	1	NA	NA	0.20836	1	0.48418	1	0.74379	1	0.29015	1	1	1	0.13672	1
ABCA8	12 (5%)	211	0.00154	0.581	0.02404	1	0.0113	1	NA	NA	0.03059	1	0.2858	1	0.4778	1	0.16168	1	0.49505	1	0.36844	1
SETD2	13 (6%)	210	0.03448	1	0.1844	1	0.00106	0.404	NA	NA	0.093689	1	0.73981	1	0.065289	1	0.01755	1	1	1	0.44168	1
ESR1	11 (5%)	212	0.19323	1	0.01026	1	0.04983	1	NA	NA	0.71796	1	0.28554	1	0.80665	1	0.19389	1	1	1	0.17889	1