Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.022 0.17 -9999.0 0.0 -0.634 28.0 28.0 MAP3K8 0.009 0.031 -9999.0 0.0 -0.518 2.0 2.0 FOS -0.023 0.156 -9999.0 0.0 -0.59 30.0 30.0 PRKCA 0.01 0.031 -9999.0 0.0 -0.518 2.0 2.0 PTPN7 -0.048 0.166 -9999.0 0.0 -0.495 71.0 71.0 HRAS 0.008 0.041 -9999.0 0.0 -0.487 4.0 4.0 PRKCB -0.04 0.162 -9999.0 0.0 -0.541 56.0 56.0 NRAS 0.001 0.076 -9999.0 0.0 -0.581 10.0 10.0 RAS family/GTP 0.011 0.069 -9999.0 0.0 -0.411 13.0 13.0 MAPK3 -0.02 0.139 -9999.0 0.0 -0.628 23.0 23.0 MAP2K1 -0.007 0.118 -9999.0 0.0 -0.42 40.0 40.0 ELK1 0.01 0.025 -9999.0 0.0 -0.58 1.0 1.0 BRAF -0.013 0.117 -9999.0 0.0 -0.427 40.0 40.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 41.0 41.0 MAPK1 -0.02 0.139 -9999.0 0.0 -0.628 23.0 23.0 RAF1 -0.012 0.114 -9999.0 0.0 -0.422 39.0 39.0 KRAS 0.006 0.057 -9999.0 0.0 -0.56 6.0 6.0