Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.006 0.116 0.352 52.0 -9999.0 0.0 52.0 KIRREL -0.002 0.108 -9999.0 0.0 -0.437 32.0 32.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.006 0.116 -9999.0 0.0 -0.353 52.0 52.0 PLCG1 0.014 0.023 -9999.0 0.0 -0.445 1.0 1.0 ARRB2 0.022 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.019 0.12 -9999.0 0.0 -0.278 76.0 76.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.003 0.084 -9999.0 0.0 -0.261 51.0 51.0 FYN -0.024 0.09 0.205 24.0 -0.254 54.0 78.0 mol:Ca2+ 0.015 0.087 -9999.0 0.0 -0.276 37.0 37.0 mol:DAG 0.016 0.088 -9999.0 0.0 -0.277 37.0 37.0 NPHS2 -0.005 0.037 -9999.0 0.0 -0.142 3.0 3.0 mol:IP3 0.016 0.088 -9999.0 0.0 -0.277 37.0 37.0 regulation of endocytosis 0.018 0.089 -9999.0 0.0 -0.239 54.0 54.0 Nephrin/NEPH1/podocin/Cholesterol 0.021 0.094 0.166 1.0 -0.265 51.0 52.0 establishment of cell polarity 0.006 0.116 -9999.0 0.0 -0.352 52.0 52.0 Nephrin/NEPH1/podocin/NCK1-2 0.046 0.1 -9999.0 0.0 -0.253 52.0 52.0 Nephrin/NEPH1/beta Arrestin2 0.02 0.091 -9999.0 0.0 -0.242 54.0 54.0 NPHS1 0.001 0.107 -9999.0 0.0 -0.449 28.0 28.0 Nephrin/NEPH1/podocin 0.021 0.093 -9999.0 0.0 -0.255 54.0 54.0 TJP1 0.024 0.02 -9999.0 0.0 -0.445 1.0 1.0 NCK1 0.024 0.028 -9999.0 0.0 -0.445 2.0 2.0 NCK2 0.025 0.019 -9999.0 0.0 -0.445 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.016 0.089 -9999.0 0.0 -0.278 37.0 37.0 CD2AP 0.004 0.099 -9999.0 0.0 -0.445 27.0 27.0 Nephrin/NEPH1/podocin/GRB2 0.034 0.1 -9999.0 0.0 -0.269 51.0 51.0 GRB2 0.025 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.038 0.102 0.219 22.0 -0.28 63.0 85.0 cytoskeleton organization -0.021 0.094 0.198 5.0 -0.31 49.0 54.0 Nephrin/NEPH1 0.01 0.083 -9999.0 0.0 -0.245 52.0 52.0 Nephrin/NEPH1/ZO-1 0.021 0.101 -9999.0 0.0 -0.286 52.0 52.0