Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.129 0.204 0.442 20.0 -9999.0 0.0 20.0 KIRREL -0.023 0.121 -9999.0 0.0 -0.718 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.129 0.205 -9999.0 0.0 -0.442 20.0 20.0 PLCG1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.107 0.157 -9999.0 0.0 -0.411 10.0 10.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.049 0.124 -9999.0 0.0 -0.324 9.0 9.0 FYN -0.084 0.153 -9999.0 0.0 -0.386 10.0 10.0 mol:Ca2+ -0.106 0.155 -9999.0 0.0 -0.408 10.0 10.0 mol:DAG -0.107 0.156 -9999.0 0.0 -0.41 10.0 10.0 NPHS2 -0.042 0.133 -9999.0 0.0 -0.516 5.0 5.0 mol:IP3 -0.107 0.156 -9999.0 0.0 -0.41 10.0 10.0 regulation of endocytosis -0.089 0.133 -9999.0 0.0 -0.359 10.0 10.0 Nephrin/NEPH1/podocin/Cholesterol -0.11 0.16 -9999.0 0.0 -0.419 10.0 10.0 establishment of cell polarity -0.129 0.204 -9999.0 0.0 -0.442 20.0 20.0 Nephrin/NEPH1/podocin/NCK1-2 -0.096 0.141 -9999.0 0.0 -0.389 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 -0.09 0.134 -9999.0 0.0 -0.363 10.0 10.0 NPHS1 -0.149 0.266 -9999.0 0.0 -0.591 18.0 18.0 Nephrin/NEPH1/podocin -0.098 0.145 -9999.0 0.0 -0.388 10.0 10.0 TJP1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.107 0.157 -9999.0 0.0 -0.411 10.0 10.0 CD2AP 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.107 0.157 -9999.0 0.0 -0.411 10.0 10.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.088 0.158 -9999.0 0.0 -0.381 11.0 11.0 cytoskeleton organization -0.063 0.158 -9999.0 0.0 -0.404 10.0 10.0 Nephrin/NEPH1 -0.092 0.148 -9999.0 0.0 -0.317 20.0 20.0 Nephrin/NEPH1/ZO-1 -0.101 0.163 -9999.0 0.0 -0.426 10.0 10.0