Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		MIR_CNMF		MIR_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	79 (28%)	204	0.00072999	0.197	9.9999e-06	0.00286	0.0013	0.347	0.14993	1	4e-05	0.0111	7.9999e-05	0.0222	0.03817	1	0.0090199	1	0.00181	0.481	0.00181	0.481
PIK3R1	32 (11%)	251	0.75195	1	0.19098	1	0.19643	1	0.52859	1	0.13316	1	0.58191	1	0.98829	1	0.67774	1	0.40312	1	0.22153	1
RB1	24 (8%)	259	0.03433	1	0.01718	1	0.13363	1	0.92256	1	0.04782	1	0.25822	1	0.49233	1	0.22684	1	0.082229	1	0.57671	1
NF1	29 (10%)	254	0.081089	1	0.00025	0.068	0.02508	1	0.93202	1	0.0096899	1	0.00227	0.597	0.22827	1	0.0059199	1	0.56473	1	0.45065	1
PTEN	87 (31%)	196	0.11554	1	0.074209	1	0.02663	1	0.64648	1	0.38724	1	0.83622	1	0.37749	1	0.14371	1	0.26971	1	0.64717	1
IDH1	14 (5%)	269	0.00011	0.0302	9.9999e-06	0.00286	3e-05	0.00837	0.0032	0.835	9.9999e-06	0.00286	0.00107	0.288	0.00348	0.901	0.00109	0.292	0.00069999	0.19	9.9999e-06	0.00286
PIK3CA	29 (10%)	254	0.79001	1	0.16283	1	0.56941	1	1	1	0.90411	1	0.17005	1	0.75554	1	0.31371	1	0.26588	1	0.23731	1
STAG2	12 (4%)	271	0.39487	1	0.69834	1	0.71521	1	0.59234	1	0.75709	1	0.85256	1	0.0070899	1	0.3919	1	0.47831	1	0.10206	1
SEMG1	8 (3%)	275	0.67736	1	0.17524	1	0.89013	1	1	1	0.1459	1	NA	NA	NA	NA	NA	NA	1	1	0.33728	1
RPL5	7 (2%)	276	0.37915	1	0.50738	1	0.86894	1	0.46756	1	1	1	1	1	0.84302	1	0.68645	1	0.46331	1	1	1
SLC26A3	7 (2%)	276	0.94123	1	0.76855	1	0.46217	1	0.3668	1	0.64025	1	NA	NA	0.16763	1	0.15316	1	0.15662	1	0.16515	1
MAP3K1	6 (2%)	277	1	1	0.7292	1	0.80656	1	0.64361	1	1	1	NA	NA	NA	NA	NA	NA	0.56923	1	1	1
ATRX	16 (6%)	267	0.00235	0.616	2e-05	0.0056	0.0066899	1	0.01817	1	9.9999e-06	0.00286	0.14712	1	0.0057699	1	0.050349	1	0.00193	0.51	0.00023	0.0628
BRAF	6 (2%)	277	0.76902	1	0.71297	1	0.31678	1	0.02962	1	0.59084	1	NA	NA	1	1	0.64177	1	0.7944	1	1	1
EGFR	74 (26%)	209	0.0072199	1	0.057439	1	0.51097	1	0.139	1	9.9999e-06	0.00286	0.0082999	1	8.9999e-05	0.0248	0.00011	0.0302	0.04174	1	0.0057899	1
PDGFRA	11 (4%)	272	0.01313	1	0.14359	1	0.90584	1	0.13789	1	0.46409	1	NA	NA	1	1	1	1	0.02636	1	0.00465	1
KDR	8 (3%)	275	0.20474	1	0.65452	1	0.27688	1	0.51156	1	0.49561	1	1	1	0.14475	1	0.52798	1	NA	NA	NA	NA
TMPRSS6	6 (2%)	277	0.66769	1	0.69905	1	0.66154	1	0.26432	1	0.77502	1	0.78049	1	0.25348	1	0.32335	1	0.57368	1	1	1
CHD8	9 (3%)	274	0.70273	1	0.53157	1	0.1352	1	0.64699	1	0.1933	1	1	1	0.62383	1	0.75915	1	0.27667	1	0.61052	1
SEMA3C	11 (4%)	272	0.48178	1	0.1733	1	0.12147	1	0.84965	1	0.50618	1	NA	NA	0.33836	1	0.68629	1	0.10345	1	0.169	1
ZDHHC4	3 (1%)	280	NA	NA	NA	NA	0.16434	1	1	1	0.054129	1	0.35634	1	NA	NA	NA	NA	NA	NA	NA	NA
MMP13	5 (2%)	278	0.91169	1	0.21751	1	0.76637	1	0.0483	1	0.15471	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
PRKCD	3 (1%)	280	0.17366	1	0.084019	1	0.16357	1	1	1	0.38858	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
REN	5 (2%)	278	0.47664	1	0.41459	1	0.074609	1	0.51007	1	0.62404	1	0.18421	1	1	1	0.83745	1	NA	NA	NA	NA
LRRC55	6 (2%)	277	0.37781	1	0.53645	1	0.33254	1	0.86815	1	0.326	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
MUC17	22 (8%)	261	0.01272	1	0.19231	1	0.70517	1	0.70114	1	0.96054	1	0.44791	1	0.24465	1	0.32821	1	0.85963	1	1	1
CD209	5 (2%)	278	0.91113	1	1	1	0.066609	1	0.60814	1	0.69117	1	0.48519	1	0.48967	1	1	1	NA	NA	NA	NA
DDX5	4 (1%)	279	0.21616	1	1	1	0.54208	1	0.44497	1	0.14512	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
TP63	6 (2%)	277	1	1	0.7318	1	0.40543	1	0.64691	1	0.77311	1	0.55812	1	0.066979	1	0.20815	1	0.25327	1	0.10958	1
CD1D	4 (1%)	279	0.8788	1	1	1	0.64409	1	0.12288	1	0.82785	1	1	1	0.89297	1	1	1	NA	NA	NA	NA
LZTR1	10 (4%)	273	1	1	0.51336	1	0.35897	1	0.70493	1	0.4385	1	0.37034	1	0.83918	1	0.89425	1	0.17041	1	0.75144	1
TEX15	8 (3%)	275	0.30987	1	0.24296	1	0.29935	1	0.71952	1	0.55113	1	0.35652	1	0.8685	1	0.27171	1	0.00322	0.837	0.82342	1
FBN3	11 (4%)	272	0.19071	1	0.30892	1	0.90356	1	0.9212	1	0.18159	1	0.45841	1	0.28145	1	0.37584	1	0.85635	1	1	1