Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_2q11.2 104 (20%) 407 9.9999e-06 0.0073 9.9999e-06 0.0073 0.50546 1 0.542 1 0.050989 1 0.00034 0.182 0.066569 1 0.00105 0.538 0.14496 1 9.9999e-06 0.0073 amp_2q31.2 108 (21%) 403 9.9999e-06 0.0073 9.9999e-06 0.0073 0.23928 1 0.31674 1 0.19002 1 0.01274 1 0.19835 1 0.0058299 1 0.33353 1 3e-05 0.0172 amp_3q26.33 372 (73%) 139 9.9999e-06 0.0073 9.9999e-06 0.0073 0.12996 1 0.31068 1 9.9999e-06 0.0073 6.9999e-05 0.0392 0.00018 0.0986 0.21612 1 0.04408 1 4e-05 0.0228 amp_5p15.33 231 (45%) 280 9.9999e-06 0.0073 9.9999e-06 0.0073 0.85456 1 0.8277 1 0.1568 1 0.17652 1 0.70011 1 0.079889 1 0.96514 1 0.80409 1 amp_5p12 203 (40%) 308 9.9999e-06 0.0073 4e-05 0.0228 0.58241 1 0.1888 1 0.30608 1 0.10955 1 0.58308 1 0.0346 1 0.99258 1 0.73901 1 amp_6p12.1 107 (21%) 404 9.9999e-06 0.0073 2e-05 0.0118 0.45946 1 0.95166 1 0.85706 1 0.0143 1 0.45436 1 0.00124 0.629 0.92888 1 0.057119 1 amp_6q12 92 (18%) 419 9.9999e-06 0.0073 0.00029 0.156 0.27486 1 0.90085 1 0.86775 1 0.16081 1 0.30118 1 0.22066 1 0.80888 1 0.58804 1 amp_7p11.2 215 (42%) 296 9.9999e-06 0.0073 9.9999e-06 0.0073 0.99737 1 0.67099 1 0.04806 1 0.01055 1 0.71713 1 9.9999e-06 0.0073 0.26642 1 9.9999e-05 0.0554 amp_7q21.3 164 (32%) 347 9.9999e-06 0.0073 9.9999e-06 0.0073 0.33235 1 0.44129 1 0.30687 1 0.28158 1 0.086099 1 0.00027 0.146 0.28775 1 0.00021 0.114 amp_8p11.23 156 (31%) 355 9.9999e-06 0.0073 0.0064599 1 0.80992 1 0.87263 1 0.12469 1 0.01149 1 0.00314 1 0.050779 1 0.29371 1 0.03757 1 amp_8q11.21 305 (60%) 206 9.9999e-06 0.0073 9.9999e-06 0.0073 0.097749 1 0.63439 1 0.00184 0.922 0.00011 0.0607 0.03257 1 0.00028 0.151 0.04788 1 0.00103 0.529 amp_8q24.21 379 (74%) 132 9.9999e-06 0.0073 9.9999e-06 0.0073 0.31742 1 0.44717 1 0.01308 1 2e-05 0.0118 0.064019 1 0.00025 0.135 0.00203 1 7.9999e-05 0.0447 amp_9p24.1 122 (24%) 389 9.9999e-06 0.0073 2e-05 0.0118 0.13735 1 0.24994 1 0.00266 1 0.00103 0.529 0.03475 1 0.0039 1 0.16264 1 0.00432 1 amp_9p23 121 (24%) 390 9.9999e-06 0.0073 2e-05 0.0118 0.38622 1 0.42418 1 0.00361 1 0.00379 1 0.060089 1 0.0068799 1 0.27405 1 0.04835 1 amp_9p13.3 135 (26%) 376 9.9999e-06 0.0073 0.0029 1 0.48477 1 0.12223 1 0.00088999 0.462 0.01595 1 0.00326 1 0.03731 1 0.83947 1 0.21155 1 amp_9q34.3 174 (34%) 337 9.9999e-06 0.0073 0.01717 1 0.23814 1 0.02425 1 0.95574 1 0.38267 1 0.7096 1 0.15815 1 0.93055 1 0.68462 1 amp_11p13 101 (20%) 410 2e-04 0.109 0.00142 0.716 0.46067 1 0.17939 1 0.95818 1 0.22293 1 0.81748 1 0.53616 1 0.31286 1 0.056999 1 amp_11q13.3 223 (44%) 288 9.9999e-06 0.0073 9.9999e-06 0.0073 0.83381 1 0.72821 1 0.16906 1 0.13032 1 0.4127 1 0.0075999 1 0.25734 1 0.21979 1 amp_12p13.33 162 (32%) 349 9.9999e-06 0.0073 9.9999e-06 0.0073 0.04183 1 0.52085 1 0.0091899 1 0.00218 1 0.02237 1 0.02016 1 0.16733 1 0.00259 1 amp_12q15 101 (20%) 410 9.9999e-06 0.0073 0.00057999 0.306 0.067429 1 0.20357 1 0.12684 1 0.067749 1 0.92045 1 0.15254 1 1 1 0.3928 1 amp_13q22.1 104 (20%) 407 9.9999e-06 0.0073 2e-05 0.0118 0.14758 1 0.15593 1 0.32545 1 0.28801 1 0.44001 1 0.02723 1 0.83998 1 0.02644 1 amp_13q34 106 (21%) 405 9.9999e-06 0.0073 5.9999e-05 0.0338 0.25278 1 0.28926 1 0.20186 1 0.28115 1 0.3518 1 0.01202 1 0.33769 1 0.03564 1 amp_15q26.3 102 (20%) 409 0.00169 0.848 0.0087399 1 0.45623 1 0.32813 1 0.60403 1 0.98197 1 0.33936 1 0.0122 1 0.6897 1 0.14637 1 amp_17q12 88 (17%) 423 9.9999e-06 0.0073 9.9999e-06 0.0073 0.18569 1 0.71862 1 0.01073 1 0.01891 1 0.0096499 1 0.00051999 0.277 1 1 0.0074499 1 amp_18p11.31 152 (30%) 359 9.9999e-06 0.0073 9.9999e-06 0.0073 0.52257 1 0.51647 1 0.083279 1 9.9999e-06 0.0073 0.76957 1 5e-04 0.266 0.57157 1 9.9999e-06 0.0073 amp_18q11.2 101 (20%) 410 9.9999e-06 0.0073 7.9999e-05 0.0447 0.51812 1 0.20489 1 0.36843 1 0.01401 1 0.03728 1 0.053689 1 0.82307 1 0.02001 1 amp_20p12.2 189 (37%) 322 4e-05 0.0228 5e-05 0.0283 0.87275 1 0.93431 1 0.089069 1 0.0093799 1 0.15111 1 0.0089599 1 0.0228 1 0.04113 1 amp_20q11.22 224 (44%) 287 9.9999e-06 0.0073 2e-05 0.0118 0.50269 1 0.83341 1 0.10546 1 0.01064 1 0.47071 1 0.01886 1 0.2345 1 0.063999 1 amp_xq28 145 (28%) 366 9.9999e-06 0.0073 2e-05 0.0118 0.639 1 0.19887 1 0.3045 1 0.14726 1 0.15575 1 0.02951 1 0.94948 1 0.0242 1 del_1p36.21 94 (18%) 417 9.9999e-06 0.0073 9.9999e-06 0.0073 0.00081999 0.428 0.0057199 1 9.9999e-06 0.0073 5.9999e-05 0.0338 0.00092999 0.482 0.067499 1 0.04211 1 9.9999e-06 0.0073 del_1p13.2 127 (25%) 384 9.9999e-06 0.0073 9.9999e-06 0.0073 0.02386 1 0.0074699 1 0.02626 1 0.37659 1 0.01823 1 0.00052999 0.281 0.098159 1 2e-05 0.0118 del_1q44 47 (9%) 464 0.00093999 0.486 0.01681 1 0.7305 1 0.90794 1 0.01393 1 0.0042 1 0.00059999 0.316 0.04784 1 0.02296 1 0.27694 1 del_2q21.2 73 (14%) 438 0.82796 1 0.01083 1 0.70272 1 0.20976 1 0.02622 1 0.0067099 1 0.00029 0.156 0.18444 1 0.065729 1 0.070779 1 del_2q22.1 114 (22%) 397 0.068229 1 9.9999e-05 0.0554 0.34824 1 0.83845 1 0.27914 1 0.25354 1 0.1806 1 0.0086499 1 0.89559 1 0.1343 1 del_2q36.2 152 (30%) 359 9.9999e-06 0.0073 9.9999e-06 0.0073 0.092919 1 0.85584 1 0.01074 1 0.01383 1 0.090139 1 0.03302 1 0.12908 1 0.0098099 1 del_3p24.1 357 (70%) 154 9.9999e-06 0.0073 9.9999e-06 0.0073 0.41749 1 0.11501 1 0.0016 0.805 2e-05 0.0118 0.0077099 1 9.9999e-06 0.0073 0.11203 1 9.9999e-06 0.0073 del_3p12.1 332 (65%) 179 9.9999e-06 0.0073 9.9999e-06 0.0073 0.82955 1 0.90076 1 0.01993 1 5e-05 0.0283 0.075169 1 0.00011 0.0607 0.33978 1 9.9999e-06 0.0073 del_4p15.2 201 (39%) 310 9.9999e-06 0.0073 9.9999e-06 0.0073 0.01123 1 0.33674 1 8.9999e-05 0.05 0.00054999 0.291 0.052019 1 0.0062699 1 0.00376 1 9.9999e-06 0.0073 del_4q22.1 164 (32%) 347 9.9999e-06 0.0073 9.9999e-06 0.0073 0.24676 1 0.077039 1 0.0096699 1 0.00272 1 0.21455 1 0.01713 1 0.48589 1 9.9999e-06 0.0073 del_4q35.2 206 (40%) 305 9.9999e-06 0.0073 4e-05 0.0228 0.8424 1 0.18748 1 0.012 1 0.11847 1 0.32347 1 0.00102 0.526 0.41434 1 0.00054999 0.291 del_5q11.2 209 (41%) 302 9.9999e-06 0.0073 9.9999e-06 0.0073 0.13237 1 0.48647 1 0.098459 1 9.9999e-06 0.0073 0.18714 1 9.9999e-06 0.0073 0.38337 1 9.9999e-06 0.0073 del_5q15 219 (43%) 292 9.9999e-06 0.0073 9.9999e-06 0.0073 0.14364 1 0.43424 1 0.10703 1 9.9999e-06 0.0073 0.23545 1 2e-05 0.0118 0.62244 1 9.9999e-06 0.0073 del_5q35.3 195 (38%) 316 9.9999e-06 0.0073 9.9999e-06 0.0073 0.2401 1 0.72022 1 0.01927 1 9.9999e-06 0.0073 0.3434 1 9.9999e-06 0.0073 0.45381 1 9.9999e-06 0.0073 del_6p25.3 93 (18%) 418 0.00034 0.182 9.9999e-06 0.0073 0.04307 1 0.01063 1 0.00226 1 0.096679 1 0.19285 1 0.39594 1 0.6833 1 0.065019 1 del_7q31.1 74 (14%) 437 0.0062099 1 0.17539 1 0.57249 1 0.38062 1 0.51357 1 0.21656 1 0.87366 1 0.33225 1 0.56843 1 0.84613 1 del_7q36.1 127 (25%) 384 0.00014 0.0769 0.36909 1 0.04448 1 0.67587 1 0.77085 1 0.70578 1 0.62393 1 0.3116 1 0.74289 1 0.76122 1 del_8p23.2 294 (58%) 217 9.9999e-06 0.0073 9.9999e-06 0.0073 0.27881 1 0.32475 1 0.00121 0.615 5e-05 0.0283 0.00218 1 0.00067999 0.356 0.00022 0.119 9.9999e-06 0.0073 del_9p23 233 (46%) 278 9.9999e-06 0.0073 9.9999e-06 0.0073 0.28052 1 0.11311 1 0.82146 1 0.00024 0.13 0.7695 1 0.00029 0.156 0.25237 1 9.9999e-06 0.0073 del_9p21.3 292 (57%) 219 9.9999e-06 0.0073 9.9999e-06 0.0073 0.67097 1 0.36065 1 0.14703 1 9.9999e-06 0.0073 1 1 9.9999e-06 0.0073 0.10817 1 9.9999e-06 0.0073 del_9q21.11 103 (20%) 408 9.9999e-06 0.0073 9.9999e-06 0.0073 0.98258 1 0.23666 1 0.85448 1 0.02604 1 0.73159 1 0.00053999 0.286 0.48011 1 0.00267 1 del_9q34.3 76 (15%) 435 9.9999e-06 0.0073 0.00109 0.557 0.61168 1 0.36849 1 0.43953 1 0.0476 1 0.72921 1 0.02169 1 0.20177 1 0.01976 1 del_10p15.3 165 (32%) 346 9.9999e-06 0.0073 9.9999e-06 0.0073 0.60788 1 0.57475 1 0.12673 1 0.15334 1 0.14401 1 0.02719 1 0.098639 1 0.00102 0.526 del_10p11.21 152 (30%) 359 9.9999e-06 0.0073 9.9999e-06 0.0073 0.448 1 0.17298 1 0.27662 1 0.74638 1 0.01659 1 0.04574 1 0.13336 1 0.00118 0.601 del_10q23.31 134 (26%) 377 2e-05 0.0118 9.9999e-06 0.0073 0.13322 1 0.97837 1 8.9999e-05 0.05 9.9999e-06 0.0073 0.0073399 1 0.33683 1 0.04607 1 0.055769 1 del_11p15.5 156 (31%) 355 9.9999e-06 0.0073 9.9999e-06 0.0073 0.86585 1 0.281 1 7.9999e-05 0.0447 0.00267 1 9.9999e-06 0.0073 0.01789 1 0.15917 1 3e-05 0.0172 del_11q23.1 239 (47%) 272 9.9999e-06 0.0073 9.9999e-06 0.0073 0.087679 1 0.16536 1 9.9999e-06 0.0073 9.9999e-06 0.0073 0.00206 1 0.03289 1 0.02275 1 0.0090599 1 del_12q24.33 60 (12%) 451 2e-05 0.0118 2e-05 0.0118 0.61635 1 0.45666 1 0.86661 1 0.56243 1 0.48942 1 0.39873 1 0.062609 1 0.43318 1 del_13q12.11 224 (44%) 287 9.9999e-06 0.0073 9.9999e-06 0.0073 0.14811 1 0.31464 1 0.02459 1 4e-05 0.0228 0.83243 1 0.01837 1 0.58874 1 0.00126 0.636 del_13q14.2 209 (41%) 302 9.9999e-06 0.0073 9.9999e-06 0.0073 0.11125 1 0.56551 1 9.9999e-06 0.0073 9.9999e-06 0.0073 0.0037 1 0.42164 1 0.19904 1 0.00078999 0.413 del_14q11.2 72 (14%) 439 0.00342 1 0.01157 1 0.32394 1 0.89834 1 0.11726 1 0.27665 1 0.03474 1 0.02161 1 0.16116 1 0.0092899 1 del_14q32.32 73 (14%) 438 0.00019 0.104 9.9999e-06 0.0073 0.01768 1 0.46732 1 2e-05 0.0118 9.9999e-06 0.0073 0.003 1 0.01752 1 0.01927 1 0.00364 1 del_15q15.1 119 (23%) 392 9.9999e-06 0.0073 0.20231 1 0.67055 1 0.41081 1 0.071169 1 0.082269 1 0.80103 1 0.5108 1 0.68964 1 0.16972 1 del_16q23.3 102 (20%) 409 0.00124 0.629 9.9999e-06 0.0073 0.16047 1 0.23167 1 9.9999e-06 0.0073 9.9999e-06 0.0073 0.00432 1 0.14329 1 0.0062299 1 0.051789 1 del_17q25.3 68 (13%) 443 0.03803 1 9.9999e-06 0.0073 0.4343 1 0.69365 1 0.01267 1 0.00339 1 0.00367 1 0.03044 1 0.00489 1 0.10259 1 del_18q21.2 259 (51%) 252 9.9999e-06 0.0073 9.9999e-06 0.0073 0.89889 1 0.37885 1 0.0069499 1 9.9999e-06 0.0073 0.01811 1 9.9999e-06 0.0073 0.19326 1 9.9999e-06 0.0073 del_18q23 278 (54%) 233 9.9999e-06 0.0073 9.9999e-06 0.0073 0.25596 1 0.24504 1 0.0056499 1 9.9999e-06 0.0073 0.02372 1 9.9999e-06 0.0073 0.075029 1 9.9999e-06 0.0073 del_19p13.3 165 (32%) 346 9.9999e-06 0.0073 9.9999e-06 0.0073 0.44849 1 0.46158 1 0.01893 1 0.01611 1 0.22338 1 5.9999e-05 0.0338 0.53816 1 0.00087999 0.458 del_19q13.43 94 (18%) 417 9.9999e-06 0.0073 9.9999e-06 0.0073 0.33127 1 0.58946 1 0.88242 1 0.3443 1 0.62401 1 0.01207 1 0.60931 1 0.059189 1 del_21q22.3 195 (38%) 316 9.9999e-06 0.0073 9.9999e-06 0.0073 0.61217 1 0.93522 1 0.04491 1 0.065299 1 0.60871 1 3e-05 0.0172 0.91422 1 0.00021 0.114 del_22q13.31 84 (16%) 427 0.00113 0.576 0.02768 1 0.68797 1 0.89213 1 0.02004 1 0.52433 1 0.011 1 0.21029 1 0.12604 1 0.00188 0.94 del_xp22.2 152 (30%) 359 9.9999e-06 0.0073 9.9999e-06 0.0073 0.31804 1 0.00223 1 0.085939 1 0.0057299 1 0.01707 1 0.098809 1 0.39172 1 0.01347 1 del_xp21.3 154 (30%) 357 9.9999e-06 0.0073 9.9999e-06 0.0073 0.55978 1 0.054899 1 0.46834 1 0.01346 1 0.20793 1 0.077209 1 0.74212 1 0.0088399 1 del_xq21.33 74 (14%) 437 2e-05 0.0118 9.9999e-06 0.0073 0.49072 1 0.17144 1 0.00086999 0.453 0.01432 1 0.00011 0.0607 0.071239 1 0.21681 1 0.00063999 0.336