Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	213 (70%)	93	9.9999e-06	0.0027	9.9999e-06	0.0027	0.084209	1	0.89021	1	0.0085499	1	9.9999e-06	0.0027	0.02476	1	9.9999e-06	0.0027	0.086059	1	2e-05	0.00522
CDKN2A	65 (21%)	241	0.085559	1	0.00054999	0.14	0.00104	0.262	0.53472	1	0.18809	1	0.39657	1	0.37524	1	0.11927	1	0.35311	1	0.41998	1
CASP8	27 (9%)	279	9.9999e-06	0.0027	9.9999e-06	0.0027	0.01451	1	0.38638	1	9.9999e-06	0.0027	5e-05	0.013	0.13664	1	1	1	0.49918	1	0.04735	1
FAT1	69 (23%)	237	0.33885	1	0.077549	1	0.91817	1	0.48046	1	0.10376	1	0.32261	1	0.097959	1	0.40919	1	0.87232	1	0.097679	1
MLL2	53 (17%)	253	0.01124	1	0.04899	1	0.49023	1	0.3481	1	0.081429	1	0.10651	1	0.069159	1	0.0080499	1	0.090569	1	0.098869	1
JUB	18 (6%)	288	0.42398	1	0.080639	1	0.39661	1	0.74494	1	0.11961	1	0.42032	1	0.083459	1	0.95149	1	0.04259	1	0.74664	1
NOTCH1	57 (19%)	249	0.2288	1	0.00119	0.299	0.055079	1	0.070179	1	0.00202	0.501	9.9999e-05	0.0258	5e-05	0.013	0.38304	1	0.01787	1	0.0423	1
NFE2L2	17 (6%)	289	0.92195	1	0.00011	0.0283	0.35102	1	0.684	1	1	1	0.43572	1	0.29981	1	0.5121	1	0.31559	1	0.52439	1
NSD1	33 (11%)	273	0.02961	1	9.9999e-06	0.0027	0.093469	1	0.0062299	1	0.00027	0.0688	9.9999e-06	0.0027	0.01397	1	0.00099999	0.253	0.03496	1	0.02247	1
HRAS	10 (3%)	296	0.00016	0.041	0.00496	1	0.38831	1	0.34272	1	0.00129	0.322	0.01488	1	0.54282	1	0.078199	1	0.75642	1	0.01492	1
ZNF750	13 (4%)	293	0.44547	1	0.13637	1	0.80562	1	0.32955	1	0.080809	1	0.068779	1	0.81344	1	0.87399	1	0.37018	1	0.50551	1
RASA1	14 (5%)	292	0.2991	1	0.13081	1	0.37722	1	0.71373	1	0.34656	1	0.54873	1	0.49383	1	0.15374	1	0.079099	1	0.29992	1
HLA-A	9 (3%)	297	0.075239	1	0.31435	1	1	1	0.64198	1	0.1864	1	0.072509	1	0.20169	1	0.17136	1	0.54199	1	0.0283	1
EPHA2	13 (4%)	293	0.56077	1	0.00161	0.401	0.74049	1	0.93107	1	0.064209	1	0.19885	1	0.34484	1	0.13156	1	0.72736	1	0.46591	1
RAC1	9 (3%)	297	0.078349	1	0.43556	1	1	1	0.83728	1	0.1892	1	0.15116	1	0.25008	1	0.13594	1	0.32559	1	0.24544	1
EP300	24 (8%)	282	0.23394	1	0.46631	1	0.57281	1	0.084959	1	0.00433	1	0.059529	1	0.41988	1	0.21558	1	1	1	0.24312	1
TGFBR2	10 (3%)	296	0.16414	1	0.01136	1	0.43499	1	0.90123	1	0.22874	1	0.04339	1	1	1	0.84809	1	0.66165	1	0.77261	1
PIK3CA	64 (21%)	242	0.02876	1	0.04031	1	0.697	1	0.04783	1	0.096479	1	0.052889	1	0.0094699	1	0.070059	1	0.079629	1	0.54365	1
FBXW7	15 (5%)	291	0.69677	1	0.47419	1	0.41364	1	0.11103	1	0.63379	1	0.8754	1	0.83719	1	0.11223	1	1	1	0.9351	1
RB1	10 (3%)	296	0.0075899	1	0.38257	1	0.32686	1	0.27667	1	0.054649	1	0.37814	1	0.14216	1	0.38327	1	0.42184	1	0.2789	1
CTCF	11 (4%)	295	0.27883	1	0.0373	1	0.61622	1	0.46692	1	0.42707	1	0.5221	1	0.79266	1	0.58144	1	0.46885	1	0.92124	1
KDM6A	8 (3%)	298	0.079869	1	0.63023	1	0.15532	1	1	1	0.90789	1	0.36004	1	0.2598	1	0.8157	1	0.27105	1	0.064099	1
ELF4	5 (2%)	301	0.14124	1	0.17186	1	0.35584	1	0.33688	1	0.61763	1	1	1	0.28835	1	0.37371	1	0.85276	1	0.27494	1
RHOA	4 (1%)	302	0.23673	1	0.16648	1	0.13903	1	0.24148	1	0.82331	1	0.48716	1	0.078049	1	0.4611	1	0.11316	1	0.10034	1
HLA-B	8 (3%)	298	0.23326	1	0.40291	1	1	1	0.051909	1	0.0080899	1	0.1478	1	0.26158	1	0.074309	1	0.052899	1	0.01806	1
PRSS1	7 (2%)	299	0.80256	1	0.85333	1	0.87457	1	0.61521	1	0.72071	1	0.57658	1	0.88634	1	0.01093	1	0.16405	1	0.38122	1
GUCY2F	8 (3%)	298	1	1	0.95903	1	0.82988	1	0.83532	1	0.66745	1	0.87852	1	0.51759	1	0.66404	1	0.0050699	1	0.054869	1