Clinical feature	Statistical test	Significant variables	Associated with	&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;	Associated with	
AGE	Spearman correlation test	N=2	older	N=2	younger	N=0
AGE_mutation rate	Linear Regression Analysis	N=1	 	 	 	 
NEOPLASM DISEASESTAGE	Kruskal-Wallis test	N=2	 	 	 	 
PATHOLOGY T STAGE	Spearman correlation test	N=2	higher stage	N=2	lower stage	N=0
PATHOLOGY N STAGE	Spearman correlation test	N=2	higher stage	N=2	lower stage	N=0
PATHOLOGY M STAGE	Kruskal-Wallis test	N=0	 	 	 	 
GENDER	Wilcoxon test	N=0	 	 	 	 
KARNOFSKY PERFORMANCE SCORE	Spearman correlation test	N=0	 	 	 	 
NUMBERPACKYEARSSMOKED	Spearman correlation test	N=0	 	 	 	 
RACE	Kruskal-Wallis test	N=0	 	 	 	 
ETHNICITY	Wilcoxon test	N=1	not hispanic or latino	N=1	hispanic or latino	N=0
