Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.443 0.216 0.532 55.0 -9999.0 0.0 55.0 KIRREL -0.092 0.14 -9999.0 0.0 -0.701 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.444 0.216 -9999.0 0.0 -0.533 55.0 55.0 PLCG1 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.03 0.028 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.443 0.261 -9999.0 0.0 -0.519 57.0 57.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.391 0.23 -9999.0 0.0 -0.464 55.0 55.0 FYN -0.424 0.233 -9999.0 0.0 -0.489 57.0 57.0 mol:Ca2+ -0.436 0.258 -9999.0 0.0 -0.517 56.0 56.0 mol:DAG -0.439 0.26 -9999.0 0.0 -0.52 56.0 56.0 NPHS2 -0.299 0.312 -9999.0 0.0 -0.698 25.0 25.0 mol:IP3 -0.439 0.26 -9999.0 0.0 -0.52 56.0 56.0 regulation of endocytosis -0.393 0.236 -9999.0 0.0 -0.462 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.443 0.256 -9999.0 0.0 -0.517 57.0 57.0 establishment of cell polarity -0.443 0.216 -9999.0 0.0 -0.532 55.0 55.0 Nephrin/NEPH1/podocin/NCK1-2 -0.414 0.25 -9999.0 0.0 -0.488 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.399 0.241 -9999.0 0.0 -0.469 57.0 57.0 NPHS1 -0.551 0.25 -9999.0 0.0 -0.669 54.0 54.0 Nephrin/NEPH1/podocin -0.421 0.246 -9999.0 0.0 -0.492 57.0 57.0 TJP1 0.023 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.023 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.023 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.441 0.262 -9999.0 0.0 -0.523 56.0 56.0 CD2AP 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.443 0.261 -9999.0 0.0 -0.519 57.0 57.0 GRB2 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.412 0.234 -9999.0 0.0 -0.486 55.0 55.0 cytoskeleton organization -0.489 0.266 -9999.0 0.0 -0.575 55.0 55.0 Nephrin/NEPH1 -0.325 0.164 -9999.0 0.0 -0.391 55.0 55.0 Nephrin/NEPH1/ZO-1 -0.364 0.188 -9999.0 0.0 -0.441 55.0 55.0