Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q SETD2 44 (11%) 373 1 1 0.49947 1 0.66757 1 9.9999e-06 0.00269 0.63949 1 0.16068 1 0.46366 1 0.079959 1 0.77766 1 0.76221 1 0.62091 1 0.059239 1 BAP1 41 (10%) 376 0.03147 1 0.00054999 0.143 0.011 1 0.00012 0.0314 0.00084999 0.218 0.065979 1 4e-05 0.0106 9.9999e-06 0.00269 6.9999e-05 0.0184 9.9999e-06 0.00269 0.35145 1 0.03709 1 PTEN 18 (4%) 399 0.10653 1 0.03194 1 0.21215 1 0.16843 1 0.25877 1 0.15583 1 0.00097999 0.25 0.00111 0.282 0.0086699 1 0.04102 1 0.01573 1 0.055189 1 PBRM1 136 (33%) 281 0.15257 1 0.058969 1 0.13849 1 3e-05 0.00795 0.00070999 0.183 0.25326 1 0.0064199 1 0.02703 1 0.00379 0.947 0.059869 1 9.9999e-06 0.00269 0.054469 1 KDM5C 26 (6%) 391 NA NA NA NA 0.1879 1 0.089129 1 0.43588 1 0.75554 1 0.10946 1 0.00068999 0.179 0.00426 1 0.63496 1 0.37369 1 0.1368 1 VHL 166 (40%) 251 0.11269 1 0.22556 1 0.1145 1 0.74847 1 0.77404 1 0.39266 1 0.01397 1 0.51342 1 0.16079 1 0.00267 0.673 0.67212 1 0.15908 1 FAM200A 5 (1%) 412 NA NA NA NA 0.0014 0.354 NA NA 0.03102 1 0.3179 1 0.15889 1 0.41152 1 0.20738 1 0.58607 1 NA NA NA NA TP53 9 (2%) 408 NA NA NA NA 0.76701 1 0.5109 1 0.5145 1 0.64792 1 0.45567 1 0.31149 1 0.46355 1 0.17312 1 0.22748 1 0.27091 1 NEFH 5 (1%) 412 NA NA NA NA 0.85751 1 0.54033 1 0.97796 1 0.11611 1 0.01243 1 0.01619 1 0.61791 1 0.40501 1 0.68288 1 1 1 CCDC120 4 (1%) 413 NA NA NA NA 0.1829 1 NA NA 0.56427 1 0.79354 1 0.67453 1 0.81596 1 0.82235 1 1 1 0.61342 1 0.16254 1 MTOR 23 (6%) 394 NA NA NA NA 0.56459 1 0.15436 1 0.00047 0.123 0.00075999 0.195 0.65689 1 0.4475 1 0.34497 1 0.03263 1 0.064699 1 0.0033 0.828 GUSB 4 (1%) 413 NA NA NA NA 0.68375 1 NA NA 0.44852 1 0.44649 1 0.1846 1 0.1947 1 0.45884 1 0.51564 1 NA NA NA NA PIK3CA 12 (3%) 405 NA NA NA NA 0.29446 1 0.65505 1 0.88856 1 0.73023 1 0.28654 1 0.53725 1 0.75121 1 0.80036 1 0.61248 1 0.60524 1 PCK1 5 (1%) 412 NA NA NA NA 0.22658 1 0.61454 1 1 1 0.68469 1 0.84751 1 0.68196 1 0.72437 1 0.4883 1 NA NA NA NA ARID1A 12 (3%) 405 NA NA NA NA 0.65611 1 0.26135 1 0.96892 1 0.92954 1 0.30759 1 0.64622 1 0.11574 1 0.070969 1 0.28346 1 0.84752 1 ATM 11 (3%) 406 NA NA NA NA 0.50833 1 0.47581 1 0.51201 1 0.70717 1 0.21737 1 0.6158 1 0.11382 1 0.52562 1 0.078209 1 0.04543 1 DPCR1 6 (1%) 411 NA NA NA NA 0.45312 1 0.51461 1 0.10085 1 0.49506 1 0.108 1 0.0085399 1 0.6752 1 0.40692 1 0.65386 1 0.8668 1 FGFR3 4 (1%) 413 NA NA NA NA 0.57183 1 0.83928 1 0.94965 1 0.79234 1 0.82762 1 0.47938 1 0.82126 1 0.31324 1 NA NA NA NA PTCH1 7 (2%) 410 NA NA NA NA 0.63284 1 0.054879 1 0.28088 1 0.11946 1 0.87701 1 0.10062 1 0.79639 1 0.21741 1 NA NA NA NA RBMX 4 (1%) 413 NA NA NA NA 0.57089 1 0.61861 1 0.098489 1 0.5991 1 0.40682 1 0.48381 1 0.2507 1 0.17329 1 NA NA NA NA ARAP3 3 (1%) 414 NA NA NA NA 0.62496 1 NA NA 1 1 0.79494 1 0.78407 1 1 1 0.79621 1 1 1 NA NA NA NA GPR172B 4 (1%) 413 NA NA NA NA 1 1 NA NA 0.077759 1 1 1 0.52862 1 1 1 0.61109 1 0.4335 1 NA NA NA NA EGFR 7 (2%) 410 NA NA NA NA 1 1 0.68297 1 0.62284 1 0.37776 1 0.46535 1 0.88764 1 1 1 0.75163 1 NA NA NA NA IL1RAP 4 (1%) 413 NA NA NA NA 1 1 0.61565 1 0.29434 1 0.073939 1 0.82861 1 0.81406 1 0.56628 1 0.82282 1 NA NA NA NA BCL6 5 (1%) 412 NA NA NA NA 0.22943 1 0.61594 1 0.72372 1 0.14443 1 1 1 0.80442 1 0.72608 1 0.85469 1 1 1 1 1 NFAT5 6 (1%) 411 NA NA NA NA 0.76788 1 0.87728 1 0.2697 1 0.71809 1 0.29721 1 0.43065 1 0.24255 1 1 1 NA NA NA NA LARP1 5 (1%) 412 NA NA NA NA 0.85668 1 0.43772 1 0.17862 1 0.71943 1 0.84808 1 0.86407 1 0.61675 1 0.2701 1 NA NA NA NA KIAA1751 6 (1%) 411 NA NA NA NA 0.67505 1 0.63892 1 0.53201 1 0.053519 1 0.40467 1 0.92987 1 0.49625 1 0.16931 1 0.79208 1 0.16144 1 INSRR 4 (1%) 413 NA NA NA NA 0.57058 1 0.1205 1 0.348 1 0.68458 1 0.40556 1 0.23856 1 0.46017 1 0.24902 1 NA NA NA NA