Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.485 0.261 0.621 402.0 -9999.0 0.0 402.0 KIRREL -0.055 0.106 -9999.0 0.0 -0.821 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.486 0.261 -9999.0 0.0 -0.622 402.0 402.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.039 -9999.0 0.0 -0.864 1.0 1.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.529 0.31 -9999.0 0.0 -0.841 224.0 224.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.409 0.261 -9999.0 0.0 -0.665 224.0 224.0 FYN -0.498 0.301 -9999.0 0.0 -0.798 224.0 224.0 mol:Ca2+ -0.522 0.305 -9999.0 0.0 -0.827 224.0 224.0 mol:DAG -0.526 0.307 -9999.0 0.0 -0.834 224.0 224.0 NPHS2 -0.409 0.383 -9999.0 0.0 -0.807 248.0 248.0 mol:IP3 -0.526 0.307 -9999.0 0.0 -0.834 224.0 224.0 regulation of endocytosis -0.469 0.278 -9999.0 0.0 -0.749 224.0 224.0 Nephrin/NEPH1/podocin/Cholesterol -0.538 0.313 -9999.0 0.0 -0.65 429.0 429.0 establishment of cell polarity -0.485 0.261 -9999.0 0.0 -0.621 402.0 402.0 Nephrin/NEPH1/podocin/NCK1-2 -0.488 0.292 -9999.0 0.0 -0.784 224.0 224.0 Nephrin/NEPH1/beta Arrestin2 -0.477 0.285 -9999.0 0.0 -0.765 224.0 224.0 NPHS1 -0.608 0.326 -9999.0 0.0 -0.784 400.0 400.0 Nephrin/NEPH1/podocin -0.506 0.297 -9999.0 0.0 -0.805 224.0 224.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.033 -9999.0 0.0 -0.746 1.0 1.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.529 0.31 -9999.0 0.0 -0.841 224.0 224.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.529 0.31 -9999.0 0.0 -0.841 224.0 224.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.488 0.3 -9999.0 0.0 -0.788 224.0 224.0 cytoskeleton organization -0.528 0.319 -9999.0 0.0 -0.848 224.0 224.0 Nephrin/NEPH1 -0.364 0.199 -9999.0 0.0 -0.466 402.0 402.0 Nephrin/NEPH1/ZO-1 -0.394 0.216 -9999.0 0.0 -0.505 402.0 402.0