Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.377 0.223 0.503 379.0 -9999.0 0.0 379.0 KIRREL -0.059 0.082 -9999.0 0.0 -0.599 8.0 8.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.378 0.224 -9999.0 0.0 -0.504 379.0 379.0 PLCG1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.029 -9999.0 0.0 -0.621 1.0 1.0 WASL 0.026 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.396 0.268 -9999.0 0.0 -0.513 400.0 400.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.332 0.229 -9999.0 0.0 -0.444 375.0 375.0 FYN -0.38 0.243 0.265 1.0 -0.482 404.0 405.0 mol:Ca2+ -0.387 0.266 -9999.0 0.0 -0.506 397.0 397.0 mol:DAG -0.389 0.268 -9999.0 0.0 -0.509 397.0 397.0 NPHS2 -0.326 0.314 -9999.0 0.0 -0.662 235.0 235.0 mol:IP3 -0.389 0.268 -9999.0 0.0 -0.509 397.0 397.0 regulation of endocytosis -0.354 0.239 -9999.0 0.0 -0.459 397.0 397.0 Nephrin/NEPH1/podocin/Cholesterol -0.4 0.265 -9999.0 0.0 -0.513 404.0 404.0 establishment of cell polarity -0.377 0.223 -9999.0 0.0 -0.503 379.0 379.0 Nephrin/NEPH1/podocin/NCK1-2 -0.36 0.257 -9999.0 0.0 -0.617 210.0 210.0 Nephrin/NEPH1/beta Arrestin2 -0.359 0.243 -9999.0 0.0 -0.466 397.0 397.0 NPHS1 -0.493 0.273 -9999.0 0.0 -0.641 392.0 392.0 Nephrin/NEPH1/podocin -0.378 0.252 -9999.0 0.0 -0.485 404.0 404.0 TJP1 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.029 -9999.0 0.0 -0.611 1.0 1.0 NCK2 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.391 0.27 -9999.0 0.0 -0.512 397.0 397.0 CD2AP 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.393 0.269 -9999.0 0.0 -0.513 398.0 398.0 GRB2 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.372 0.243 0.276 1.0 -0.477 398.0 399.0 cytoskeleton organization -0.415 0.274 -9999.0 0.0 -0.561 358.0 358.0 Nephrin/NEPH1 -0.273 0.166 -9999.0 0.0 -0.366 379.0 379.0 Nephrin/NEPH1/ZO-1 -0.301 0.191 -9999.0 0.0 -0.41 377.0 377.0