Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.041 0.113 0.377 2.0 -0.567 9.0 11.0 MAP3K8 0.026 0.034 -9999.0 0.0 -0.503 2.0 2.0 FOS 0.028 0.099 0.354 4.0 -0.526 8.0 12.0 PRKCA 0.028 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 -0.006 0.132 -9999.0 0.0 -0.506 33.0 33.0 HRAS 0.028 0.024 -9999.0 0.0 -0.503 1.0 1.0 PRKCB 0.022 0.058 -9999.0 0.0 -0.555 5.0 5.0 NRAS 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.052 0.022 -9999.0 0.0 -0.276 1.0 1.0 MAPK3 0.016 0.085 -9999.0 0.0 -0.501 9.0 9.0 MAP2K1 0.026 0.051 -9999.0 0.0 -0.483 2.0 2.0 ELK1 0.028 0.009 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.026 0.037 -9999.0 0.0 -0.438 2.0 2.0 mol:GTP 0.0 0.002 -9999.0 0.0 -0.007 13.0 13.0 MAPK1 0.016 0.087 -9999.0 0.0 -0.542 7.0 7.0 RAF1 0.019 0.038 -9999.0 0.0 -0.438 2.0 2.0 KRAS 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0