Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.487 0.354 0.721 142.0 -9999.0 0.0 142.0 KIRREL -0.123 0.244 -9999.0 0.0 -0.872 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.489 0.355 -9999.0 0.0 -0.723 142.0 142.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.02 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.537 0.38 -9999.0 0.0 -0.715 160.0 160.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.409 0.314 -9999.0 0.0 -0.553 160.0 160.0 FYN -0.504 0.365 -9999.0 0.0 -0.676 160.0 160.0 mol:Ca2+ -0.529 0.372 -9999.0 0.0 -0.704 160.0 160.0 mol:DAG -0.533 0.376 -9999.0 0.0 -0.71 160.0 160.0 NPHS2 -0.381 0.408 -9999.0 0.0 -0.869 87.0 87.0 mol:IP3 -0.533 0.376 -9999.0 0.0 -0.71 160.0 160.0 regulation of endocytosis -0.472 0.345 -9999.0 0.0 -0.635 160.0 160.0 Nephrin/NEPH1/podocin/Cholesterol -0.543 0.383 -9999.0 0.0 -0.722 160.0 160.0 establishment of cell polarity -0.487 0.354 -9999.0 0.0 -0.721 142.0 142.0 Nephrin/NEPH1/podocin/NCK1-2 -0.5 0.359 -9999.0 0.0 -0.666 160.0 160.0 Nephrin/NEPH1/beta Arrestin2 -0.482 0.355 -9999.0 0.0 -0.648 160.0 160.0 NPHS1 -0.552 0.401 -9999.0 0.0 -0.853 136.0 136.0 Nephrin/NEPH1/podocin -0.512 0.366 -9999.0 0.0 -0.683 160.0 160.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.537 0.38 -9999.0 0.0 -0.715 160.0 160.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.537 0.38 -9999.0 0.0 -0.715 160.0 160.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.606 0.404 -9999.0 0.0 -0.755 172.0 172.0 cytoskeleton organization -0.53 0.393 -9999.0 0.0 -0.715 160.0 160.0 Nephrin/NEPH1 -0.374 0.281 -9999.0 0.0 -0.555 142.0 142.0 Nephrin/NEPH1/ZO-1 -0.407 0.303 -9999.0 0.0 -0.604 142.0 142.0