Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.382 0.291 0.571 141.0 -9999.0 0.0 141.0 KIRREL -0.112 0.197 -9999.0 0.0 -0.698 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.382 0.292 -9999.0 0.0 -0.572 141.0 141.0 PLCG1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.401 0.317 -9999.0 0.0 -0.563 155.0 155.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.335 0.263 -9999.0 0.0 -0.486 140.0 140.0 FYN -0.395 0.279 0.266 1.0 -0.533 155.0 156.0 mol:Ca2+ -0.395 0.311 -9999.0 0.0 -0.562 151.0 151.0 mol:DAG -0.398 0.314 -9999.0 0.0 -0.565 151.0 151.0 NPHS2 -0.314 0.325 -9999.0 0.0 -0.711 84.0 84.0 mol:IP3 -0.398 0.314 -9999.0 0.0 -0.565 151.0 151.0 regulation of endocytosis -0.359 0.281 -9999.0 0.0 -0.506 152.0 152.0 Nephrin/NEPH1/podocin/Cholesterol -0.407 0.31 -9999.0 0.0 -0.564 155.0 155.0 establishment of cell polarity -0.382 0.291 -9999.0 0.0 -0.571 141.0 141.0 Nephrin/NEPH1/podocin/NCK1-2 -0.375 0.303 -9999.0 0.0 -0.53 154.0 154.0 Nephrin/NEPH1/beta Arrestin2 -0.365 0.287 -9999.0 0.0 -0.515 152.0 152.0 NPHS1 -0.454 0.319 -9999.0 0.0 -0.691 135.0 135.0 Nephrin/NEPH1/podocin -0.387 0.297 -9999.0 0.0 -0.537 155.0 155.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.4 0.316 -9999.0 0.0 -0.569 151.0 151.0 CD2AP 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.398 0.314 -9999.0 0.0 -0.568 150.0 150.0 GRB2 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.468 0.308 0.275 1.0 -0.591 166.0 167.0 cytoskeleton organization -0.412 0.318 -9999.0 0.0 -0.597 142.0 142.0 Nephrin/NEPH1 -0.282 0.224 -9999.0 0.0 -0.425 141.0 141.0 Nephrin/NEPH1/ZO-1 -0.312 0.253 -9999.0 0.0 -0.483 137.0 137.0