Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.104 0.244 29.0 -9999.0 0.0 29.0 KIRREL -0.05 0.136 -9999.0 0.0 -0.343 29.0 29.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.104 -9999.0 0.0 -0.245 29.0 29.0 PLCG1 0.019 0.063 -9999.0 0.0 -0.335 5.0 5.0 ARRB2 0.029 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.028 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.009 0.093 -9999.0 0.0 -0.186 29.0 29.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.018 0.08 -9999.0 0.0 -0.189 29.0 29.0 FYN -0.024 0.085 0.235 6.0 -0.174 29.0 35.0 mol:Ca2+ -0.0 0.097 -9999.0 0.0 -0.188 33.0 33.0 mol:DAG 0.001 0.098 -9999.0 0.0 -0.188 33.0 33.0 NPHS2 -0.001 0.028 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.001 0.098 -9999.0 0.0 -0.188 33.0 33.0 regulation of endocytosis 0.004 0.084 -9999.0 0.0 -0.163 31.0 31.0 Nephrin/NEPH1/podocin/Cholesterol -0.005 0.081 -9999.0 0.0 -0.177 29.0 29.0 establishment of cell polarity -0.021 0.104 -9999.0 0.0 -0.244 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 0.024 0.091 -9999.0 0.0 -0.166 29.0 29.0 Nephrin/NEPH1/beta Arrestin2 0.006 0.085 -9999.0 0.0 -0.165 31.0 31.0 NPHS1 0.001 0.029 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.004 0.083 0.175 1.0 -0.17 32.0 33.0 TJP1 -0.002 0.094 -9999.0 0.0 -0.335 12.0 12.0 NCK1 0.031 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.032 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.002 0.099 -9999.0 0.0 -0.189 33.0 33.0 CD2AP 0.03 0.029 -9999.0 0.0 -0.335 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 0.009 0.09 -9999.0 0.0 -0.18 29.0 29.0 GRB2 0.03 0.008 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.032 0.066 0.154 3.0 -0.164 28.0 31.0 cytoskeleton organization -0.03 0.084 0.203 2.0 -0.202 29.0 31.0 Nephrin/NEPH1 -0.01 0.072 -9999.0 0.0 -0.163 29.0 29.0 Nephrin/NEPH1/ZO-1 -0.019 0.102 -9999.0 0.0 -0.197 40.0 40.0