Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.002 0.093 0.315 37.0 -9999.0 0.0 37.0 KIRREL -0.009 0.119 -9999.0 0.0 -0.43 37.0 37.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.002 0.093 -9999.0 0.0 -0.315 37.0 37.0 PLCG1 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.02 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.029 0.079 -9999.0 0.0 -0.234 37.0 37.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.003 0.068 -9999.0 0.0 -0.244 31.0 31.0 FYN -0.009 0.075 0.18 22.0 -0.223 38.0 60.0 mol:Ca2+ 0.026 0.078 -9999.0 0.0 -0.232 38.0 38.0 mol:DAG 0.027 0.079 -9999.0 0.0 -0.233 38.0 38.0 NPHS2 0.001 0.032 -9999.0 0.0 -0.277 2.0 2.0 mol:IP3 0.027 0.079 -9999.0 0.0 -0.233 38.0 38.0 regulation of endocytosis 0.024 0.071 -9999.0 0.0 -0.211 38.0 38.0 Nephrin/NEPH1/podocin/Cholesterol 0.016 0.074 -9999.0 0.0 -0.232 38.0 38.0 establishment of cell polarity -0.002 0.093 -9999.0 0.0 -0.315 37.0 37.0 Nephrin/NEPH1/podocin/NCK1-2 0.039 0.08 -9999.0 0.0 -0.22 37.0 37.0 Nephrin/NEPH1/beta Arrestin2 0.025 0.072 -9999.0 0.0 -0.213 38.0 38.0 NPHS1 -0.0 0.051 -9999.0 0.0 -0.254 6.0 6.0 Nephrin/NEPH1/podocin 0.018 0.072 -9999.0 0.0 -0.224 38.0 38.0 TJP1 0.025 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.024 0.02 -9999.0 0.0 -0.424 1.0 1.0 NCK2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.028 0.08 -9999.0 0.0 -0.234 38.0 38.0 CD2AP 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.027 0.079 -9999.0 0.0 -0.234 37.0 37.0 GRB2 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.013 0.085 0.19 25.0 -0.231 45.0 70.0 cytoskeleton organization -0.016 0.082 0.202 12.0 -0.267 31.0 43.0 Nephrin/NEPH1 0.01 0.065 -9999.0 0.0 -0.216 37.0 37.0 Nephrin/NEPH1/ZO-1 0.022 0.08 -9999.0 0.0 -0.249 37.0 37.0