Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.042 0.202 -9999.0 0.0 -0.425 88.0 88.0 MAP3K8 0.015 0.047 -9999.0 0.0 -0.425 4.0 4.0 FOS -0.04 0.179 -9999.0 0.0 -0.443 69.0 69.0 PRKCA 0.02 0.024 -9999.0 0.0 -0.425 1.0 1.0 PTPN7 -0.053 0.15 -9999.0 0.0 -0.282 124.0 124.0 HRAS 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.01 0.097 -9999.0 0.0 -0.217 68.0 68.0 NRAS 0.021 0.01 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.033 0.025 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.032 0.161 -9999.0 0.0 -0.427 66.0 66.0 MAP2K1 0.003 0.101 -9999.0 0.0 -0.425 20.0 20.0 ELK1 0.021 0.017 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.006 0.085 -9999.0 0.0 -0.386 22.0 22.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 61.0 61.0 MAPK1 -0.034 0.166 -9999.0 0.0 -0.432 67.0 67.0 RAF1 -0.001 0.082 -9999.0 0.0 -0.396 19.0 19.0 KRAS 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0