Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.034 0.156 -9999.0 0.0 -0.292 5.0 5.0 MAP3K8 0.006 0.088 -9999.0 0.0 -0.271 2.0 2.0 FOS -0.008 0.09 -9999.0 0.0 -9999.0 0.0 0.0 PRKCA 0.021 0.022 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.012 0.04 -9999.0 0.0 -0.14 1.0 1.0 HRAS 0.029 0.012 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.004 0.007 -9999.0 0.0 -0.012 11.0 11.0 NRAS 0.026 0.014 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.036 0.029 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.023 0.054 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K1 0.013 0.06 -9999.0 0.0 -9999.0 0.0 0.0 ELK1 0.017 0.029 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.006 0.019 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 8.0 8.0 MAPK1 -0.002 0.084 -9999.0 0.0 -9999.0 0.0 0.0 RAF1 0.004 0.022 -9999.0 0.0 -9999.0 0.0 0.0 KRAS 0.029 0.012 -9999.0 0.0 -9999.0 0.0 0.0