Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.125	0.274	0.521	52.0	-0.587	6.0	58.0
IHH	0.065	0.168	0.349	20.0	-0.632	6.0	26.0
SHH Np/Cholesterol/GAS1	-0.052	0.158	-9999.0	0.0	-0.417	28.0	28.0
LRPAP1	0.025	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.051	0.157	0.413	28.0	-9999.0	0.0	28.0
SMO/beta Arrestin2	0.065	0.215	0.413	9.0	-0.566	13.0	22.0
SMO	0.053	0.226	0.401	19.0	-0.581	14.0	33.0
AKT1	0.047	0.172	0.306	6.0	-0.51	8.0	14.0
ARRB2	0.022	0.009	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.033	0.05	0.347	5.0	-9999.0	0.0	5.0
ADRBK1	0.025	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.054	0.223	0.4	19.0	-0.57	14.0	33.0
STIL	0.092	0.198	0.42	25.0	-0.491	8.0	33.0
DHH N/PTCH2	0.035	0.042	0.251	2.0	-0.467	1.0	3.0
DHH N/PTCH1	0.081	0.197	0.442	14.0	-0.481	12.0	26.0
PIK3CA	0.022	0.045	-9999.0	0.0	-0.624	1.0	1.0
DHH	0.026	0.023	0.347	1.0	-9999.0	0.0	1.0
PTHLH	0.141	0.311	0.599	50.0	-0.663	6.0	56.0
determination of left/right symmetry	0.054	0.223	0.4	19.0	-0.57	14.0	33.0
PIK3R1	0.022	0.045	-9999.0	0.0	-0.624	1.0	1.0
skeletal system development	0.141	0.31	0.598	50.0	-0.657	6.0	56.0
IHH N/Hhip	-0.207	0.289	0.289	2.0	-0.493	99.0	101.0
DHH N/Hhip	-0.199	0.249	0.251	2.0	-0.455	98.0	100.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.054	0.223	0.4	19.0	-0.57	14.0	33.0
pancreas development	-0.278	0.319	0.346	1.0	-0.607	98.0	99.0
HHAT	0.017	0.046	-9999.0	0.0	-0.624	1.0	1.0
PI3K	0.033	0.061	-9999.0	0.0	-0.836	1.0	1.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.078	0.236	-9999.0	0.0	-0.615	33.0	33.0
somite specification	0.054	0.223	0.4	19.0	-0.57	14.0	33.0
SHH Np/Cholesterol/PTCH1	0.032	0.174	0.385	8.0	-0.42	16.0	24.0
SHH Np/Cholesterol/PTCH2	0.001	0.089	0.211	1.0	-0.364	10.0	11.0
SHH Np/Cholesterol/Megalin	-0.028	0.157	0.23	15.0	-0.332	36.0	51.0
SHH	-0.009	0.107	0.254	2.0	-0.512	8.0	10.0
catabolic process	0.088	0.234	0.515	19.0	-0.528	12.0	31.0
SMO/Vitamin D3	0.078	0.227	0.461	18.0	-0.536	12.0	30.0
SHH Np/Cholesterol/Hhip	-0.156	0.193	0.215	1.0	-0.338	99.0	100.0
LRP2	-0.041	0.246	0.347	15.0	-0.624	28.0	43.0
receptor-mediated endocytosis	0.016	0.224	0.389	15.0	-0.61	11.0	26.0
SHH Np/Cholesterol/BOC	0.006	0.09	0.214	4.0	-0.372	9.0	13.0
SHH Np/Cholesterol/CDO	0.001	0.087	-9999.0	0.0	-0.382	9.0	9.0
mesenchymal cell differentiation	0.155	0.191	0.336	99.0	-0.213	1.0	100.0
mol:Vitamin D3	0.092	0.211	0.474	17.0	-0.459	12.0	29.0
IHH N/PTCH2	0.052	0.115	0.275	5.0	-0.413	7.0	12.0
CDON	0.025	0.005	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/PTCH1	0.107	0.245	0.437	50.0	-0.532	12.0	62.0
Megalin/LRPAP1	-0.018	0.188	0.251	15.0	-0.467	28.0	43.0
PTCH2	0.023	0.051	0.347	1.0	-0.624	1.0	2.0
SHH Np/Cholesterol	-0.005	0.085	-9999.0	0.0	-0.382	9.0	9.0
PTCH1	0.088	0.235	0.516	19.0	-0.531	12.0	31.0
HHIP	-0.279	0.32	0.347	1.0	-0.608	98.0	99.0