Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.164 0.255 -9999.0 0.0 -0.43 74.0 74.0 MAP3K8 0.012 0.065 -9999.0 0.0 -0.626 2.0 2.0 FOS -0.094 0.183 -9999.0 0.0 -0.473 25.0 25.0 PRKCA 0.005 0.024 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.001 0.066 0.348 3.0 -0.629 1.0 4.0 HRAS 0.025 0.023 0.344 1.0 -9999.0 0.0 1.0 PRKCB -0.051 0.178 -9999.0 0.0 -0.615 18.0 18.0 NRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.017 0.038 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.055 0.153 -9999.0 0.0 -0.622 10.0 10.0 MAP2K1 -0.066 0.16 -9999.0 0.0 -0.491 22.0 22.0 ELK1 -0.002 0.031 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.05 0.147 -9999.0 0.0 -0.486 19.0 19.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.005 96.0 96.0 MAPK1 -0.048 0.138 -9999.0 0.0 -0.632 7.0 7.0 RAF1 -0.046 0.137 -9999.0 0.0 -0.469 18.0 18.0 KRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0