Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.089	0.18	0.304	6.0	-0.488	43.0	49.0
IHH	-0.013	0.123	0.27	7.0	-0.376	41.0	48.0
SHH Np/Cholesterol/GAS1	-0.011	0.066	-9999.0	0.0	-0.179	62.0	62.0
LRPAP1	0.021	0.003	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.035	0.056	0.178	62.0	-0.111	1.0	63.0
SMO/beta Arrestin2	-0.142	0.181	0.291	3.0	-0.324	187.0	190.0
SMO	-0.145	0.184	0.337	1.0	-0.333	196.0	197.0
AKT1	-0.078	0.138	0.26	1.0	-0.481	30.0	31.0
ARRB2	0.02	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.02	0.016	-9999.0	0.0	-0.321	1.0	1.0
ADRBK1	0.021	0.003	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.144	0.182	0.336	1.0	-0.329	196.0	197.0
STIL	-0.083	0.141	0.26	11.0	-0.311	64.0	75.0
DHH N/PTCH2	0.011	0.069	-9999.0	0.0	-0.225	38.0	38.0
DHH N/PTCH1	-0.106	0.151	-9999.0	0.0	-0.35	62.0	62.0
PIK3CA	0.02	0.004	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.006	0.092	-9999.0	0.0	-0.321	38.0	38.0
PTHLH	-0.122	0.219	0.368	6.0	-0.546	41.0	47.0
determination of left/right symmetry	-0.144	0.182	0.336	1.0	-0.329	196.0	197.0
PIK3R1	0.02	0.016	-9999.0	0.0	-0.321	1.0	1.0
skeletal system development	-0.121	0.218	0.367	6.0	-0.542	41.0	47.0
IHH N/Hhip	-0.217	0.177	0.206	3.0	-0.311	355.0	358.0
DHH N/Hhip	-0.121	0.142	-9999.0	0.0	-0.244	268.0	268.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.144	0.182	0.336	1.0	-0.329	196.0	197.0
pancreas development	-0.163	0.17	-9999.0	0.0	-0.32	261.0	261.0
HHAT	0.018	0.023	-9999.0	0.0	-0.321	2.0	2.0
PI3K	0.029	0.014	-9999.0	0.0	-0.226	1.0	1.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.012	0.053	-9999.0	0.0	-0.321	12.0	12.0
somite specification	-0.144	0.182	0.336	1.0	-0.329	196.0	197.0
SHH Np/Cholesterol/PTCH1	-0.094	0.137	-9999.0	0.0	-0.326	68.0	68.0
SHH Np/Cholesterol/PTCH2	-0.009	0.061	0.113	1.0	-0.173	57.0	58.0
SHH Np/Cholesterol/Megalin	-0.048	0.097	0.113	1.0	-0.189	146.0	147.0
SHH	-0.039	0.069	0.152	1.0	-0.226	57.0	58.0
catabolic process	-0.105	0.158	0.227	2.0	-0.248	231.0	233.0
SMO/Vitamin D3	-0.115	0.174	0.373	3.0	-0.395	64.0	67.0
SHH Np/Cholesterol/Hhip	-0.09	0.111	0.113	1.0	-0.196	238.0	239.0
LRP2	-0.067	0.151	0.319	1.0	-0.321	126.0	127.0
receptor-mediated endocytosis	-0.159	0.183	0.3	2.0	-0.403	124.0	126.0
SHH Np/Cholesterol/BOC	-0.008	0.06	0.113	1.0	-0.173	56.0	57.0
SHH Np/Cholesterol/CDO	-0.01	0.064	0.113	1.0	-0.177	60.0	61.0
mesenchymal cell differentiation	0.102	0.099	0.195	238.0	-0.111	1.0	239.0
mol:Vitamin D3	-0.089	0.15	0.384	5.0	-0.333	65.0	70.0
IHH N/PTCH2	-0.093	0.127	0.206	4.0	-0.207	262.0	266.0
CDON	0.014	0.046	-9999.0	0.0	-0.321	9.0	9.0
IHH N/PTCH1	-0.097	0.17	0.265	2.0	-0.25	233.0	235.0
Megalin/LRPAP1	-0.034	0.112	0.231	1.0	-0.225	123.0	124.0
PTCH2	0.02	0.016	-9999.0	0.0	-0.321	1.0	1.0
SHH Np/Cholesterol	-0.028	0.051	-9999.0	0.0	-0.167	57.0	57.0
PTCH1	-0.105	0.159	0.228	2.0	-0.249	231.0	233.0
HHIP	-0.163	0.17	-9999.0	0.0	-0.321	261.0	261.0