Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.028 0.11 0.445 31.0 -9999.0 0.0 31.0 KIRREL -0.003 0.091 -9999.0 0.0 -0.751 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.028 0.11 -9999.0 0.0 -0.445 31.0 31.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.022 0.084 -9999.0 0.0 -0.457 8.0 8.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.012 0.051 -9999.0 0.0 -0.341 7.0 7.0 FYN -0.02 0.08 -9999.0 0.0 -0.463 8.0 8.0 mol:Ca2+ -0.022 0.083 -9999.0 0.0 -0.453 8.0 8.0 mol:DAG -0.022 0.084 -9999.0 0.0 -0.455 8.0 8.0 NPHS2 -0.003 0.047 -9999.0 0.0 -0.581 3.0 3.0 mol:IP3 -0.022 0.084 -9999.0 0.0 -0.455 8.0 8.0 regulation of endocytosis -0.019 0.074 -9999.0 0.0 -0.431 8.0 8.0 Nephrin/NEPH1/podocin/Cholesterol -0.022 0.086 -9999.0 0.0 -0.464 8.0 8.0 establishment of cell polarity -0.028 0.11 -9999.0 0.0 -0.445 31.0 31.0 Nephrin/NEPH1/podocin/NCK1-2 -0.02 0.075 -9999.0 0.0 -0.416 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.019 0.075 -9999.0 0.0 -0.438 8.0 8.0 NPHS1 -0.022 0.124 -9999.0 0.0 -0.567 24.0 24.0 Nephrin/NEPH1/podocin -0.02 0.081 -9999.0 0.0 -0.465 8.0 8.0 TJP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.022 0.084 -9999.0 0.0 -0.457 8.0 8.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.022 0.084 -9999.0 0.0 -0.457 8.0 8.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.022 0.135 -9999.0 0.0 -0.496 28.0 28.0 cytoskeleton organization -0.016 0.064 -9999.0 0.0 -0.415 8.0 8.0 Nephrin/NEPH1 -0.02 0.079 -9999.0 0.0 -0.319 31.0 31.0 Nephrin/NEPH1/ZO-1 -0.022 0.087 -9999.0 0.0 -0.457 8.0 8.0