Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.221 0.246 0.436 19.0 -9999.0 0.0 19.0 KIRREL -0.088 0.208 -9999.0 0.0 -0.604 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.222 0.246 -9999.0 0.0 -0.437 19.0 19.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.155 0.19 -9999.0 0.0 -0.367 12.0 12.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.126 0.196 -9999.0 0.0 -0.345 12.0 12.0 FYN -0.147 0.177 -9999.0 0.0 -0.349 12.0 12.0 mol:Ca2+ -0.154 0.188 -9999.0 0.0 -0.364 12.0 12.0 mol:DAG -0.155 0.189 -9999.0 0.0 -0.365 12.0 12.0 NPHS2 -0.026 0.029 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.155 0.189 -9999.0 0.0 -0.365 12.0 12.0 regulation of endocytosis -0.131 0.169 -9999.0 0.0 -0.323 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.163 0.189 -9999.0 0.0 -0.325 19.0 19.0 establishment of cell polarity -0.221 0.246 -9999.0 0.0 -0.436 19.0 19.0 Nephrin/NEPH1/podocin/NCK1-2 -0.142 0.2 -9999.0 0.0 -0.617 3.0 3.0 Nephrin/NEPH1/beta Arrestin2 -0.132 0.171 -9999.0 0.0 -0.327 12.0 12.0 NPHS1 -0.249 0.274 -9999.0 0.0 -0.536 17.0 17.0 Nephrin/NEPH1/podocin -0.147 0.178 -9999.0 0.0 -0.351 12.0 12.0 TJP1 -0.002 0.097 -9999.0 0.0 -0.573 1.0 1.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 -0.002 0.097 -9999.0 0.0 -0.573 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.155 0.19 -9999.0 0.0 -0.367 12.0 12.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.155 0.19 -9999.0 0.0 -0.367 12.0 12.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.156 0.191 -9999.0 0.0 -0.366 13.0 13.0 cytoskeleton organization -0.146 0.214 -9999.0 0.0 -0.397 12.0 12.0 Nephrin/NEPH1 -0.158 0.182 -9999.0 0.0 -0.313 19.0 19.0 Nephrin/NEPH1/ZO-1 -0.178 0.229 -9999.0 0.0 -0.422 12.0 12.0