Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.136 0.213 0.43 11.0 -9999.0 0.0 11.0 KIRREL -0.071 0.189 -9999.0 0.0 -0.534 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.137 0.213 -9999.0 0.0 -0.431 11.0 11.0 PLCG1 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.029 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.089 0.174 -9999.0 0.0 -0.328 11.0 11.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.089 0.179 -9999.0 0.0 -0.318 11.0 11.0 FYN -0.09 0.161 0.188 1.0 -0.308 11.0 12.0 mol:Ca2+ -0.09 0.172 -9999.0 0.0 -0.325 11.0 11.0 mol:DAG -0.09 0.173 -9999.0 0.0 -0.326 11.0 11.0 NPHS2 -0.016 0.042 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.09 0.173 -9999.0 0.0 -0.326 11.0 11.0 regulation of endocytosis -0.077 0.156 -9999.0 0.0 -0.292 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.095 0.168 -9999.0 0.0 -0.326 11.0 11.0 establishment of cell polarity -0.136 0.213 -9999.0 0.0 -0.43 11.0 11.0 Nephrin/NEPH1/podocin/NCK1-2 -0.083 0.188 -9999.0 0.0 -0.324 11.0 11.0 Nephrin/NEPH1/beta Arrestin2 -0.077 0.158 -9999.0 0.0 -0.295 11.0 11.0 NPHS1 -0.164 0.219 -9999.0 0.0 -0.401 15.0 15.0 Nephrin/NEPH1/podocin -0.087 0.161 -9999.0 0.0 -0.309 11.0 11.0 TJP1 0.011 0.089 -9999.0 0.0 -0.51 1.0 1.0 NCK1 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.089 -9999.0 0.0 -0.51 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.089 0.174 -9999.0 0.0 -0.328 11.0 11.0 CD2AP 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.093 0.172 -9999.0 0.0 -0.328 11.0 11.0 GRB2 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.092 0.166 0.195 1.0 -0.303 12.0 13.0 cytoskeleton organization -0.103 0.21 0.202 3.0 -0.373 11.0 14.0 Nephrin/NEPH1 -0.094 0.155 -9999.0 0.0 -0.307 11.0 11.0 Nephrin/NEPH1/ZO-1 -0.108 0.204 -9999.0 0.0 -0.373 11.0 11.0