Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.002 0.111 0.364 21.0 -9999.0 0.0 21.0 KIRREL 0.023 0.027 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.002 0.112 -9999.0 0.0 -0.365 21.0 21.0 PLCG1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.029 0.093 -9999.0 0.0 -0.274 20.0 20.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.002 0.077 -9999.0 0.0 -0.259 20.0 20.0 FYN -0.005 0.093 0.335 2.0 -0.255 22.0 24.0 mol:Ca2+ 0.026 0.094 -9999.0 0.0 -0.273 21.0 21.0 mol:DAG 0.027 0.094 -9999.0 0.0 -0.274 21.0 21.0 NPHS2 0.012 0.029 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.027 0.094 -9999.0 0.0 -0.274 21.0 21.0 regulation of endocytosis 0.024 0.084 -9999.0 0.0 -0.245 21.0 21.0 Nephrin/NEPH1/podocin/Cholesterol 0.015 0.088 -9999.0 0.0 -0.271 21.0 21.0 establishment of cell polarity 0.002 0.111 -9999.0 0.0 -0.364 21.0 21.0 Nephrin/NEPH1/podocin/NCK1-2 0.04 0.093 -9999.0 0.0 -0.253 20.0 20.0 Nephrin/NEPH1/beta Arrestin2 0.025 0.086 -9999.0 0.0 -0.248 21.0 21.0 NPHS1 -0.03 0.147 -9999.0 0.0 -0.493 23.0 23.0 Nephrin/NEPH1/podocin 0.016 0.086 -9999.0 0.0 -0.256 22.0 22.0 TJP1 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.028 0.095 -9999.0 0.0 -0.275 21.0 21.0 CD2AP 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.03 0.093 -9999.0 0.0 -0.274 20.0 20.0 GRB2 0.029 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.015 0.094 0.347 2.0 -0.252 22.0 24.0 cytoskeleton organization -0.022 0.091 0.2 1.0 -0.328 19.0 20.0 Nephrin/NEPH1 0.007 0.079 -9999.0 0.0 -0.254 21.0 21.0 Nephrin/NEPH1/ZO-1 0.017 0.096 -9999.0 0.0 -0.292 21.0 21.0