Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.044	0.201	0.457	90.0	-0.502	17.0	107.0
IHH	0.007	0.055	0.194	1.0	-0.144	8.0	9.0
SHH Np/Cholesterol/GAS1	-0.03	0.056	0.129	1.0	-0.162	86.0	87.0
LRPAP1	-0.006	0.025	0.242	3.0	-0.308	2.0	5.0
dorsoventral neural tube patterning	0.03	0.056	0.161	86.0	-0.127	1.0	87.0
SMO/beta Arrestin2	0.016	0.111	-9999.0	0.0	-0.444	8.0	8.0
SMO	0.02	0.119	-9999.0	0.0	-0.464	8.0	8.0
AKT1	-0.022	0.142	-9999.0	0.0	-0.521	7.0	7.0
ARRB2	-0.006	0.0	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.036	0.091	-9999.0	0.0	-0.308	57.0	57.0
ADRBK1	-0.006	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.02	0.118	-9999.0	0.0	-0.457	8.0	8.0
STIL	0.123	0.115	0.351	69.0	-9999.0	0.0	69.0
DHH N/PTCH2	-0.007	0.0	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	-0.02	0.056	-9999.0	0.0	-0.356	8.0	8.0
PIK3CA	0.047	0.102	0.242	122.0	-9999.0	0.0	122.0
DHH	-0.006	0.0	-9999.0	0.0	-9999.0	0.0	0.0
PTHLH	0.039	0.186	-9999.0	0.0	-9999.0	0.0	0.0
determination of left/right symmetry	0.02	0.118	-9999.0	0.0	-0.457	8.0	8.0
PIK3R1	-0.075	0.127	-9999.0	0.0	-0.308	131.0	131.0
skeletal system development	0.04	0.185	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/Hhip	0.005	0.039	0.198	4.0	-9999.0	0.0	4.0
DHH N/Hhip	-0.006	0.015	0.17	4.0	-9999.0	0.0	4.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.02	0.118	-9999.0	0.0	-0.457	8.0	8.0
pancreas development	-0.004	0.021	0.241	4.0	-9999.0	0.0	4.0
HHAT	-0.01	0.033	-9999.0	0.0	-0.308	7.0	7.0
PI3K	-0.015	0.115	0.17	98.0	-0.212	107.0	205.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.049	0.106	-9999.0	0.0	-0.308	81.0	81.0
somite specification	0.02	0.118	-9999.0	0.0	-0.457	8.0	8.0
SHH Np/Cholesterol/PTCH1	0.014	0.102	-9999.0	0.0	-0.318	8.0	8.0
SHH Np/Cholesterol/PTCH2	-0.009	0.018	0.129	1.0	-0.158	7.0	8.0
SHH Np/Cholesterol/Megalin	0.03	0.07	0.151	139.0	-0.158	5.0	144.0
SHH	-0.009	0.024	0.198	1.0	-0.212	7.0	8.0
catabolic process	0.026	0.134	0.3	90.0	-0.397	8.0	98.0
SMO/Vitamin D3	0.014	0.111	-9999.0	0.0	-0.406	8.0	8.0
SHH Np/Cholesterol/Hhip	-0.008	0.022	0.146	5.0	-0.158	7.0	12.0
LRP2	0.056	0.107	0.242	141.0	-9999.0	0.0	141.0
receptor-mediated endocytosis	0.034	0.113	0.305	17.0	-0.426	8.0	25.0
SHH Np/Cholesterol/BOC	-0.024	0.049	0.129	1.0	-0.161	63.0	64.0
SHH Np/Cholesterol/CDO	-0.007	0.026	0.147	8.0	-0.158	9.0	17.0
mesenchymal cell differentiation	0.008	0.022	0.158	7.0	-0.144	5.0	12.0
mol:Vitamin D3	0.016	0.107	-9999.0	0.0	-0.319	8.0	8.0
IHH N/PTCH2	0.003	0.035	-9999.0	0.0	-9999.0	0.0	0.0
CDON	-0.004	0.033	0.242	7.0	-0.308	2.0	9.0
IHH N/PTCH1	0.024	0.129	-9999.0	0.0	-0.399	8.0	8.0
Megalin/LRPAP1	0.037	0.078	0.17	144.0	-0.212	2.0	146.0
PTCH2	-0.006	0.0	-9999.0	0.0	-9999.0	0.0	0.0
SHH Np/Cholesterol	-0.007	0.017	-9999.0	0.0	-0.156	7.0	7.0
PTCH1	0.027	0.135	0.301	90.0	-0.398	8.0	98.0
HHIP	-0.004	0.021	0.242	4.0	-9999.0	0.0	4.0