Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.031	0.209	0.503	81.0	-0.45	15.0	96.0
IHH	-0.005	0.079	0.161	88.0	-9999.0	0.0	88.0
SHH Np/Cholesterol/GAS1	-0.045	0.037	0.144	1.0	-0.13	77.0	78.0
LRPAP1	0.028	0.007	-9999.0	0.0	0.0	33.0	33.0
dorsoventral neural tube patterning	0.044	0.037	0.13	77.0	-0.142	1.0	78.0
SMO/beta Arrestin2	0.025	0.134	0.297	84.0	-0.387	9.0	93.0
SMO	0.028	0.134	0.307	83.0	-0.397	9.0	92.0
AKT1	-0.024	0.147	0.273	13.0	-0.442	19.0	32.0
ARRB2	0.028	0.006	-9999.0	0.0	0.0	25.0	25.0
BOC	0.025	0.01	-9999.0	0.0	0.0	80.0	80.0
ADRBK1	0.029	0.003	-9999.0	0.0	0.0	6.0	6.0
heart looping	0.028	0.133	0.306	83.0	-0.392	9.0	92.0
STIL	0.001	0.064	0.273	20.0	-9999.0	0.0	20.0
DHH N/PTCH2	0.042	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.006	0.134	0.314	79.0	-0.291	8.0	87.0
PIK3CA	0.02	0.014	-9999.0	0.0	0.0	174.0	174.0
DHH	0.029	0.002	-9999.0	0.0	0.0	4.0	4.0
PTHLH	0.033	0.193	0.495	71.0	-0.425	14.0	85.0
determination of left/right symmetry	0.028	0.133	0.306	83.0	-0.392	9.0	92.0
PIK3R1	0.021	0.013	-9999.0	0.0	0.0	159.0	159.0
skeletal system development	0.033	0.193	0.494	71.0	-0.423	14.0	85.0
IHH N/Hhip	0.048	0.042	0.181	3.0	-9999.0	0.0	3.0
DHH N/Hhip	0.041	0.01	-9999.0	0.0	-9999.0	0.0	0.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.028	0.133	0.306	83.0	-0.392	9.0	92.0
pancreas development	0.028	0.006	-9999.0	0.0	0.0	26.0	26.0
HHAT	0.028	0.005	-9999.0	0.0	0.0	20.0	20.0
PI3K	-0.001	0.067	-9999.0	0.0	-0.162	77.0	77.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.024	0.011	-9999.0	0.0	0.0	94.0	94.0
somite specification	0.028	0.133	0.306	83.0	-0.392	9.0	92.0
SHH Np/Cholesterol/PTCH1	-0.003	0.115	0.269	75.0	-0.266	8.0	83.0
SHH Np/Cholesterol/PTCH2	-0.032	0.016	0.144	1.0	-0.129	5.0	6.0
SHH Np/Cholesterol/Megalin	-0.025	0.019	-9999.0	0.0	-0.129	4.0	4.0
SHH	-0.03	0.014	0.194	1.0	-9999.0	0.0	1.0
catabolic process	0.023	0.159	0.379	84.0	-0.317	8.0	92.0
SMO/Vitamin D3	0.004	0.122	0.261	76.0	-0.363	9.0	85.0
SHH Np/Cholesterol/Hhip	-0.032	0.017	0.144	1.0	-0.129	5.0	6.0
LRP2	0.022	0.013	-9999.0	0.0	0.0	140.0	140.0
receptor-mediated endocytosis	0.026	0.126	0.28	76.0	-0.402	8.0	84.0
SHH Np/Cholesterol/BOC	-0.04	0.032	0.144	1.0	-0.129	55.0	56.0
SHH Np/Cholesterol/CDO	-0.032	0.018	0.144	1.0	-0.129	7.0	8.0
mesenchymal cell differentiation	0.031	0.016	0.128	5.0	-0.142	1.0	6.0
mol:Vitamin D3	0.004	0.119	0.262	75.0	-0.267	8.0	83.0
IHH N/PTCH2	0.049	0.042	0.181	4.0	-9999.0	0.0	4.0
CDON	0.028	0.007	-9999.0	0.0	0.0	32.0	32.0
IHH N/PTCH1	-0.034	0.053	-9999.0	0.0	-0.318	8.0	8.0
Megalin/LRPAP1	0.03	0.023	-9999.0	0.0	-0.162	2.0	2.0
PTCH2	0.028	0.005	-9999.0	0.0	0.0	20.0	20.0
SHH Np/Cholesterol	-0.022	0.013	0.156	1.0	-0.118	5.0	6.0
PTCH1	0.023	0.159	0.38	84.0	-0.318	8.0	92.0
HHIP	0.028	0.006	-9999.0	0.0	0.0	26.0	26.0