Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.272 0.307 0.58 58.0 -9999.0 0.0 58.0 KIRREL -0.102 0.256 -9999.0 0.0 -0.788 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.272 0.308 -9999.0 0.0 -0.581 58.0 58.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.219 0.26 -9999.0 0.0 -0.533 39.0 39.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.138 0.211 -9999.0 0.0 -0.584 11.0 11.0 FYN -0.194 0.26 -9999.0 0.0 -0.512 39.0 39.0 mol:Ca2+ -0.217 0.256 -9999.0 0.0 -0.527 39.0 39.0 mol:DAG -0.218 0.258 -9999.0 0.0 -0.53 39.0 39.0 NPHS2 -0.059 0.157 -9999.0 0.0 -0.687 7.0 7.0 mol:IP3 -0.218 0.258 -9999.0 0.0 -0.53 39.0 39.0 regulation of endocytosis -0.193 0.233 -9999.0 0.0 -0.725 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.224 0.263 -9999.0 0.0 -0.542 39.0 39.0 establishment of cell polarity -0.272 0.307 -9999.0 0.0 -0.58 58.0 58.0 Nephrin/NEPH1/podocin/NCK1-2 -0.199 0.239 -9999.0 0.0 -0.735 11.0 11.0 Nephrin/NEPH1/beta Arrestin2 -0.178 0.252 -9999.0 0.0 -0.74 11.0 11.0 NPHS1 -0.272 0.352 -9999.0 0.0 -0.71 48.0 48.0 Nephrin/NEPH1/podocin -0.203 0.256 -9999.0 0.0 -0.515 39.0 39.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.219 0.26 -9999.0 0.0 -0.533 39.0 39.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.219 0.26 -9999.0 0.0 -0.533 39.0 39.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.2 0.285 -9999.0 0.0 -0.536 39.0 39.0 cytoskeleton organization -0.177 0.269 -9999.0 0.0 -0.586 24.0 24.0 Nephrin/NEPH1 -0.203 0.234 -9999.0 0.0 -0.433 58.0 58.0 Nephrin/NEPH1/ZO-1 -0.221 0.254 -9999.0 0.0 -0.529 39.0 39.0