Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.035 0.225 -9999.0 0.0 -0.484 23.0 23.0 MAP3K8 0.023 0.031 -9999.0 0.0 -0.164 4.0 4.0 FOS -0.032 0.189 -9999.0 0.0 -0.554 12.0 12.0 PRKCA 0.014 0.069 -9999.0 0.0 -0.471 3.0 3.0 PTPN7 -0.011 0.108 -9999.0 0.0 -0.297 16.0 16.0 HRAS 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.041 0.129 -9999.0 0.0 -0.232 41.0 41.0 NRAS 0.025 0.01 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.043 0.024 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.011 0.152 -9999.0 0.0 -0.544 9.0 9.0 MAP2K1 -0.013 0.138 -9999.0 0.0 -0.439 13.0 13.0 ELK1 0.023 0.019 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.016 0.133 -9999.0 0.0 -0.426 13.0 13.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 23.0 23.0 MAPK1 -0.04 0.19 -9999.0 0.0 -0.471 19.0 19.0 RAF1 -0.022 0.131 -9999.0 0.0 -0.39 16.0 16.0 KRAS 0.029 0.004 -9999.0 0.0 -9999.0 0.0 0.0