Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.202 0.262 0.472 80.0 -9999.0 0.0 80.0 KIRREL -0.122 0.251 -9999.0 0.0 -0.626 35.0 35.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.202 0.263 -9999.0 0.0 -0.472 80.0 80.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.158 0.195 -9999.0 0.0 -0.415 51.0 51.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.1 0.17 -9999.0 0.0 -0.339 51.0 51.0 FYN -0.137 0.194 -9999.0 0.0 -0.393 52.0 52.0 mol:Ca2+ -0.157 0.193 -9999.0 0.0 -0.412 51.0 51.0 mol:DAG -0.158 0.194 -9999.0 0.0 -0.414 51.0 51.0 NPHS2 -0.028 0.07 -9999.0 0.0 -0.512 3.0 3.0 mol:IP3 -0.158 0.194 -9999.0 0.0 -0.414 51.0 51.0 regulation of endocytosis -0.121 0.184 -9999.0 0.0 -0.366 51.0 51.0 Nephrin/NEPH1/podocin/Cholesterol -0.162 0.198 -9999.0 0.0 -0.417 53.0 53.0 establishment of cell polarity -0.202 0.262 -9999.0 0.0 -0.472 80.0 80.0 Nephrin/NEPH1/podocin/NCK1-2 -0.125 0.19 -9999.0 0.0 -0.375 51.0 51.0 Nephrin/NEPH1/beta Arrestin2 -0.122 0.187 -9999.0 0.0 -0.371 51.0 51.0 NPHS1 -0.181 0.272 -9999.0 0.0 -0.571 57.0 57.0 Nephrin/NEPH1/podocin -0.138 0.195 -9999.0 0.0 -0.395 52.0 52.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.158 0.195 -9999.0 0.0 -0.415 51.0 51.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.158 0.195 -9999.0 0.0 -0.415 51.0 51.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.165 0.22 -9999.0 0.0 -0.424 60.0 60.0 cytoskeleton organization -0.122 0.207 -9999.0 0.0 -0.412 51.0 51.0 Nephrin/NEPH1 -0.145 0.197 -9999.0 0.0 -0.343 80.0 80.0 Nephrin/NEPH1/ZO-1 -0.168 0.207 -9999.0 0.0 -0.434 54.0 54.0