Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.062 0.156 0.36 31.0 -9999.0 0.0 31.0 KIRREL -0.031 0.14 -9999.0 0.0 -0.372 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.062 0.156 -9999.0 0.0 -0.36 31.0 31.0 PLCG1 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.001 0.137 -9999.0 0.0 -0.271 30.0 30.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.034 0.111 -9999.0 0.0 -0.257 30.0 30.0 FYN -0.038 0.128 0.263 9.0 -0.254 32.0 41.0 mol:Ca2+ -0.0 0.137 -9999.0 0.0 -0.268 31.0 31.0 mol:DAG 0.0 0.138 -9999.0 0.0 -0.269 31.0 31.0 NPHS2 -0.003 0.043 -9999.0 0.0 -0.182 3.0 3.0 mol:IP3 0.0 0.138 -9999.0 0.0 -0.269 31.0 31.0 regulation of endocytosis -0.007 0.121 -9999.0 0.0 -0.238 32.0 32.0 Nephrin/NEPH1/podocin/Cholesterol -0.011 0.131 -9999.0 0.0 -0.269 31.0 31.0 establishment of cell polarity -0.062 0.156 -9999.0 0.0 -0.36 31.0 31.0 Nephrin/NEPH1/podocin/NCK1-2 0.005 0.132 -9999.0 0.0 -0.245 31.0 31.0 Nephrin/NEPH1/beta Arrestin2 -0.006 0.123 -9999.0 0.0 -0.24 32.0 32.0 NPHS1 -0.073 0.171 0.151 1.0 -0.302 48.0 49.0 Nephrin/NEPH1/podocin -0.009 0.127 -9999.0 0.0 -0.255 32.0 32.0 TJP1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.009 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.029 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.001 0.139 -9999.0 0.0 -0.27 31.0 31.0 CD2AP 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.002 0.137 -9999.0 0.0 -0.27 30.0 30.0 GRB2 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.046 0.137 0.267 10.0 -0.258 35.0 45.0 cytoskeleton organization -0.05 0.123 0.207 2.0 -0.299 29.0 31.0 Nephrin/NEPH1 -0.019 0.117 -9999.0 0.0 -0.25 31.0 31.0 Nephrin/NEPH1/ZO-1 -0.012 0.14 -9999.0 0.0 -0.287 31.0 31.0