Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1q21.3 31 (7%) 388 9.9999e-06 0.00616 0.00188 0.829 0.00218 0.948 0.068749 1 0.00107 0.49 0.0087499 1 0.00286 1 0.14682 1 0.00274 1 0.00129 0.582 amp_3q21.3 60 (14%) 359 9.9999e-06 0.00616 0.00448 1 0.1723 1 0.19987 1 0.00044 0.208 0.00191 0.838 0.066219 1 0.02087 1 0.057599 1 0.01932 1 amp_3q26.2 66 (16%) 353 9.9999e-06 0.00616 0.1562 1 0.1523 1 0.39674 1 0.00301 1 0.088229 1 0.16194 1 0.23325 1 0.32406 1 0.01735 1 amp_4q13.3 15 (4%) 404 9.9999e-06 0.00616 0.21929 1 0.47187 1 0.78097 1 0.053269 1 0.32012 1 0.03461 1 0.47699 1 0.00111 0.504 0.0023 0.991 amp_5q33.3 23 (5%) 396 9.9999e-06 0.00616 0.096309 1 0.075969 1 0.1143 1 0.03391 1 0.59228 1 0.49074 1 0.31196 1 0.097829 1 0.087449 1 amp_7p14.3 86 (21%) 333 9.9999e-06 0.00616 9.9999e-06 0.00616 0.35602 1 0.56231 1 9.9999e-06 0.00616 0.0063599 1 0.02512 1 0.00151 0.676 0.0066899 1 0.02764 1 amp_8p11.23 50 (12%) 369 9.9999e-06 0.00616 6.9999e-05 0.0354 0.096139 1 0.16269 1 3e-05 0.0157 0.0084699 1 0.10773 1 0.056119 1 0.00354 1 0.30807 1 amp_8q24.21 118 (28%) 301 9.9999e-06 0.00616 5.9999e-05 0.0305 0.0056099 1 0.0064599 1 9.9999e-06 0.00616 0.00012 0.0599 4e-05 0.0206 9.9999e-06 0.00616 9.9999e-06 0.00616 0.00184 0.815 amp_9q34.11 47 (11%) 372 9.9999e-06 0.00616 0.03622 1 0.055669 1 0.04368 1 0.04487 1 0.0050699 1 0.068479 1 0.00058999 0.277 0.31341 1 0.0053499 1 amp_11q13.2 35 (8%) 384 9.9999e-06 0.00616 0.054979 1 0.52095 1 0.5225 1 0.00017 0.0833 0.066129 1 0.31102 1 0.085629 1 0.03841 1 0.00136 0.611 amp_12q23.1 26 (6%) 393 0.00016 0.0787 0.0086199 1 0.055909 1 0.11213 1 0.050319 1 0.30157 1 0.086449 1 0.36987 1 0.22768 1 0.27127 1 amp_13q12.11 21 (5%) 398 0.00012 0.0599 0.055469 1 0.0437 1 0.03425 1 0.03366 1 0.091479 1 0.45844 1 0.04554 1 0.01328 1 0.00062999 0.295 amp_14q21.1 21 (5%) 398 9.9999e-06 0.00616 0.0099699 1 0.16733 1 0.17738 1 0.080999 1 0.28287 1 0.85591 1 0.18167 1 0.23176 1 0.44118 1 amp_15q11.2 13 (3%) 406 0.12061 1 0.31434 1 0.78445 1 0.78001 1 0.48173 1 0.4413 1 0.76496 1 0.863 1 0.52963 1 0.55271 1 amp_16q11.2 24 (6%) 395 0.00094999 0.438 0.10641 1 1 1 1 1 0.48243 1 0.068409 1 0.03519 1 3e-04 0.145 6.9999e-05 0.0354 0.01885 1 amp_17q23.2 18 (4%) 401 5e-05 0.0256 0.57772 1 1 1 0.32453 1 0.30354 1 0.17356 1 0.2822 1 0.03316 1 0.33099 1 0.28252 1 amp_18q21.31 10 (2%) 409 0.00021 0.102 0.5684 1 0.84698 1 0.45205 1 0.10548 1 0.4426 1 0.85917 1 0.47855 1 0.47774 1 0.17022 1 amp_19q13.43 14 (3%) 405 9.9999e-06 0.00616 0.10106 1 0.45444 1 0.38731 1 0.0303 1 0.17029 1 0.20053 1 0.00468 1 0.19411 1 0.00186 0.822 amp_20q13.2 34 (8%) 385 9.9999e-06 0.00616 0.00041 0.194 0.30494 1 0.3276 1 0.0032 1 0.0089099 1 0.15693 1 0.01611 1 0.0188 1 0.00016 0.0787 amp_xp22.2 20 (5%) 399 9.9999e-06 0.00616 0.29596 1 NA NA NA NA 0.096019 1 0.20736 1 0.3586 1 0.14003 1 0.02037 1 0.02635 1 amp_xp22.11 17 (4%) 402 3e-05 0.0157 0.87159 1 NA NA NA NA 0.11764 1 0.39996 1 0.50182 1 0.17444 1 0.01179 1 0.12979 1 amp_xp22.11 17 (4%) 402 9.9999e-06 0.00616 0.9326 1 0.094279 1 0.18903 1 0.075149 1 0.34436 1 0.21806 1 0.22099 1 0.13949 1 0.085559 1 amp_xp21.1 17 (4%) 402 3e-05 0.0157 0.23274 1 0.84998 1 0.73389 1 0.13281 1 0.8131 1 0.079759 1 0.57207 1 0.0072599 1 0.01782 1 amp_xq21.1 12 (3%) 407 0.0019 0.836 0.36123 1 0.48642 1 0.64187 1 0.093789 1 0.48873 1 0.04121 1 0.58004 1 0.46288 1 0.077229 1 amp_xq21.1 10 (2%) 409 0.00328 1 0.00159 0.709 0.45117 1 1 1 0.34894 1 0.23712 1 0.89596 1 0.62452 1 0.15098 1 0.36346 1 amp_xq21.31 11 (3%) 408 4e-05 0.0206 0.30749 1 0.84841 1 0.7357 1 0.062119 1 0.30196 1 0.14964 1 0.13374 1 0.32342 1 0.11752 1 amp_xq25 10 (2%) 409 0.00168 0.748 0.03637 1 0.62104 1 0.49158 1 0.10011 1 0.17159 1 0.29657 1 0.02584 1 0.02671 1 0.11864 1 amp_xq25 13 (3%) 406 0.00124 0.56 0.19401 1 1 1 0.8821 1 0.056399 1 0.19234 1 0.47228 1 0.80753 1 0.77574 1 0.071869 1 amp_xq27.1 14 (3%) 405 0.00296 1 0.12125 1 0.4167 1 0.21606 1 0.49922 1 1 1 0.00395 1 0.077099 1 0.00076999 0.358 0.00324 1 del_1p31.3 48 (11%) 371 9.9999e-06 0.00616 9.9999e-06 0.00616 0.33458 1 0.53155 1 5e-05 0.0256 2e-05 0.0105 0.00073999 0.345 0.00257 1 0.0079599 1 0.03425 1 del_1p22.1 48 (11%) 371 9.9999e-06 0.00616 0.01949 1 0.22655 1 0.093289 1 0.02489 1 0.0078099 1 0.00324 1 0.01071 1 0.00251 1 0.04197 1 del_1q42.2 39 (9%) 380 9.9999e-06 0.00616 0.00026 0.126 0.93194 1 0.10621 1 0.91907 1 0.02425 1 0.21041 1 0.29794 1 0.066479 1 0.83195 1 del_2p22.1 34 (8%) 385 0.02999 1 0.057279 1 0.03914 1 0.065299 1 0.01015 1 0.00306 1 0.077609 1 0.2286 1 0.68949 1 0.02394 1 del_2q22.1 72 (17%) 347 9.9999e-06 0.00616 9.9999e-06 0.00616 0.02489 1 0.063349 1 9.9999e-06 0.00616 9.9999e-06 0.00616 0.01521 1 0.0063599 1 0.03661 1 7.9999e-05 0.0402 del_2q22.3 66 (16%) 353 9.9999e-06 0.00616 9.9999e-06 0.00616 0.22375 1 0.071189 1 2e-05 0.0105 9.9999e-06 0.00616 0.1416 1 0.02982 1 0.24125 1 0.064589 1 del_3p13 67 (16%) 352 0.00108 0.492 9.9999e-06 0.00616 0.83985 1 0.9198 1 9.9999e-06 0.00616 9.9999e-06 0.00616 0.10587 1 0.5442 1 0.01788 1 0.01908 1 del_3q29 26 (6%) 393 0.72397 1 0.03773 1 0.72764 1 0.13777 1 0.0073899 1 0.12748 1 0.70521 1 0.62319 1 0.84241 1 0.95497 1 del_4q28.1 34 (8%) 385 2e-05 0.0105 3e-04 0.145 0.088199 1 0.099559 1 0.00083999 0.388 0.03299 1 0.01066 1 0.15722 1 0.01651 1 0.32266 1 del_5q11.2 74 (18%) 345 9.9999e-06 0.00616 9.9999e-06 0.00616 0.00427 1 0.03139 1 0.00157 0.702 0.0025 1 0.0013 0.585 0.00012 0.0599 0.00014 0.0692 0.02374 1 del_5q13.2 76 (18%) 343 9.9999e-06 0.00616 9.9999e-06 0.00616 0.02075 1 0.18271 1 0.00106 0.487 0.057979 1 0.00274 1 0.00050999 0.24 0.00344 1 0.0081299 1 del_5q21.1 82 (20%) 337 9.9999e-06 0.00616 9.9999e-06 0.00616 0.12053 1 0.095169 1 9.9999e-06 0.00616 9.9999e-06 0.00616 0.00199 0.87 0.0142 1 0.01354 1 0.01167 1 del_6q14.3 148 (35%) 271 9.9999e-06 0.00616 9.9999e-06 0.00616 0.0079299 1 0.00224 0.97 9.9999e-06 0.00616 9.9999e-06 0.00616 0.00321 1 0.00077999 0.362 0.00057999 0.273 0.02476 1 del_7q31.33 23 (5%) 396 0.03347 1 0.054119 1 0.0271 1 0.01383 1 0.00315 1 0.01229 1 0.13463 1 0.075869 1 0.067029 1 0.03878 1 del_8p21.3 242 (58%) 177 9.9999e-06 0.00616 9.9999e-06 0.00616 0.03148 1 0.052579 1 9.9999e-06 0.00616 9.9999e-06 0.00616 9.9999e-06 0.00616 3e-05 0.0157 3e-05 0.0157 0.02217 1 del_8p11.21 136 (32%) 283 9.9999e-06 0.00616 9.9999e-06 0.00616 0.86525 1 0.43373 1 9.9999e-06 0.00616 7.9999e-05 0.0402 0.00025 0.121 2e-05 0.0105 0.00069999 0.327 0.00039 0.185 del_9p23 38 (9%) 381 9.9999e-06 0.00616 0.2144 1 0.00328 1 0.02945 1 0.00095999 0.442 0.0229 1 0.095189 1 0.53204 1 0.01746 1 0.22151 1 del_10q23.31 126 (30%) 293 9.9999e-06 0.00616 9.9999e-06 0.00616 0.065919 1 0.14201 1 9.9999e-06 0.00616 9.9999e-06 0.00616 9.9999e-06 0.00616 9.9999e-06 0.00616 0.33854 1 0.00033 0.157 del_11p11.2 28 (7%) 391 0.00034 0.162 0.33913 1 0.00295 1 0.04403 1 0.03799 1 0.01167 1 0.19085 1 0.56617 1 0.0080199 1 0.26519 1 del_11q23.2 43 (10%) 376 0.03858 1 0.074129 1 0.16655 1 0.19209 1 0.91034 1 0.97577 1 0.11987 1 0.66258 1 0.66242 1 0.5917 1 del_12p13.1 100 (24%) 319 9.9999e-06 0.00616 0.00011 0.055 0.059779 1 0.080449 1 0.00335 1 0.00215 0.937 0.00012 0.0599 9.9999e-06 0.00616 0.02167 1 0.052269 1 del_12q24.31 39 (9%) 380 0.00025 0.121 0.088649 1 1 1 0.83003 1 0.0092299 1 0.077419 1 0.53883 1 0.17324 1 0.064289 1 0.77803 1 del_13q14.13 180 (43%) 239 9.9999e-06 0.00616 9.9999e-06 0.00616 0.077269 1 0.22516 1 4e-05 0.0206 0.00021 0.102 0.00034 0.162 0.01532 1 0.0073199 1 0.088569 1 del_13q22.1 139 (33%) 280 9.9999e-06 0.00616 3e-05 0.0157 0.0086399 1 0.04262 1 0.00031 0.149 0.0051199 1 0.0145 1 0.03668 1 0.03257 1 0.04977 1 del_15q21.3 48 (11%) 371 9.9999e-06 0.00616 5.9999e-05 0.0305 0.00195 0.854 0.0063699 1 5.9999e-05 0.0305 0.00081999 0.38 0.01292 1 9.9999e-05 0.0501 9.9999e-06 0.00616 0.0067199 1 del_16q22.3 158 (38%) 261 9.9999e-06 0.00616 9.9999e-06 0.00616 0.42287 1 0.21305 1 3e-05 0.0157 9.9999e-06 0.00616 5e-05 0.0256 9.9999e-06 0.00616 0.00012 0.0599 0.00031 0.149 del_16q24.1 174 (42%) 245 9.9999e-06 0.00616 9.9999e-06 0.00616 0.67983 1 0.49565 1 9.9999e-06 0.00616 5e-05 0.0256 0.0026 1 9.9999e-06 0.00616 0.00032 0.153 0.00222 0.963 del_17p13.1 131 (31%) 288 9.9999e-06 0.00616 9.9999e-06 0.00616 0.03125 1 0.050029 1 9.9999e-06 0.00616 9.9999e-06 0.00616 0.01465 1 6.9999e-05 0.0354 0.00108 0.492 0.00228 0.985 del_17q21.31 85 (20%) 334 9.9999e-06 0.00616 9.9999e-06 0.00616 0.52264 1 0.7506 1 9.9999e-06 0.00616 9.9999e-06 0.00616 0.17016 1 0.051159 1 0.01405 1 0.38271 1 del_18q22.1 115 (27%) 304 9.9999e-06 0.00616 0.108 1 0.30853 1 0.050909 1 0.00173 0.768 0.04216 1 0.50566 1 0.00015 0.0739 0.04617 1 0.054219 1 del_19q13.2 39 (9%) 380 0.00107 0.49 0.15876 1 0.3499 1 0.36093 1 0.061269 1 0.17637 1 0.04824 1 0.00451 1 0.01439 1 0.067029 1 del_21q22.2 40 (10%) 379 0.01803 1 0.0088299 1 0.42309 1 0.76677 1 0.0023 0.991 0.00018 0.088 0.40516 1 0.23225 1 0.063999 1 0.80393 1 del_21q22.3 119 (28%) 300 9.9999e-06 0.00616 9.9999e-06 0.00616 0.11822 1 0.44754 1 9.9999e-06 0.00616 9.9999e-06 0.00616 0.0012 0.544 0.00343 1 0.24859 1 0.00026 0.126