Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.073 0.155 0.341 92.0 -9999.0 0.0 92.0 KIRREL -0.095 0.198 -9999.0 0.0 -0.462 84.0 84.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.073 0.155 -9999.0 0.0 -0.341 92.0 92.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.043 0.117 -9999.0 0.0 -0.345 11.0 11.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.033 0.108 -9999.0 0.0 -0.422 3.0 3.0 FYN -0.045 0.11 -9999.0 0.0 -0.31 11.0 11.0 mol:Ca2+ -0.044 0.116 -9999.0 0.0 -0.342 11.0 11.0 mol:DAG -0.043 0.117 -9999.0 0.0 -0.343 11.0 11.0 NPHS2 -0.011 0.049 -9999.0 0.0 -0.609 2.0 2.0 mol:IP3 -0.043 0.117 -9999.0 0.0 -0.343 11.0 11.0 regulation of endocytosis -0.034 0.104 -9999.0 0.0 -0.475 2.0 2.0 Nephrin/NEPH1/podocin/Cholesterol -0.052 0.117 -9999.0 0.0 -0.25 93.0 93.0 establishment of cell polarity -0.073 0.155 -9999.0 0.0 -0.341 92.0 92.0 Nephrin/NEPH1/podocin/NCK1-2 -0.032 0.11 -9999.0 0.0 -0.506 3.0 3.0 Nephrin/NEPH1/beta Arrestin2 -0.034 0.106 -9999.0 0.0 -0.481 2.0 2.0 NPHS1 -0.017 0.092 -9999.0 0.0 -0.59 9.0 9.0 Nephrin/NEPH1/podocin -0.045 0.11 -9999.0 0.0 -0.312 11.0 11.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.031 -9999.0 0.0 -0.591 1.0 1.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.043 0.117 -9999.0 0.0 -0.345 11.0 11.0 CD2AP 0.013 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.043 0.117 -9999.0 0.0 -0.345 11.0 11.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.081 0.158 -9999.0 0.0 -0.414 46.0 46.0 cytoskeleton organization -0.033 0.118 -9999.0 0.0 -0.46 3.0 3.0 Nephrin/NEPH1 -0.049 0.108 -9999.0 0.0 -0.236 92.0 92.0 Nephrin/NEPH1/ZO-1 -0.048 0.124 -9999.0 0.0 -0.27 57.0 57.0