Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.02 0.11 0.221 83.0 -9999.0 0.0 83.0 KIRREL -0.043 0.142 -9999.0 0.0 -0.322 76.0 76.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.02 0.111 -9999.0 0.0 -0.222 83.0 83.0 PLCG1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.017 0.099 0.195 1.0 -0.169 76.0 77.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.017 0.081 -9999.0 0.0 -0.187 67.0 67.0 FYN -0.022 0.079 0.215 12.0 -0.167 63.0 75.0 mol:Ca2+ 0.016 0.096 -9999.0 0.0 -0.167 74.0 74.0 mol:DAG 0.017 0.097 -9999.0 0.0 -0.168 74.0 74.0 NPHS2 0.005 0.034 -9999.0 0.0 -0.222 2.0 2.0 mol:IP3 0.017 0.097 -9999.0 0.0 -0.168 74.0 74.0 regulation of endocytosis 0.003 0.082 -9999.0 0.0 -0.152 74.0 74.0 Nephrin/NEPH1/podocin/Cholesterol 0.005 0.091 0.176 1.0 -0.167 76.0 77.0 establishment of cell polarity -0.02 0.11 -9999.0 0.0 -0.221 83.0 83.0 Nephrin/NEPH1/podocin/NCK1-2 0.025 0.095 -9999.0 0.0 -0.155 71.0 71.0 Nephrin/NEPH1/beta Arrestin2 0.004 0.084 -9999.0 0.0 -0.154 74.0 74.0 NPHS1 0.006 0.045 -9999.0 0.0 -0.208 9.0 9.0 Nephrin/NEPH1/podocin 0.003 0.086 -9999.0 0.0 -0.162 76.0 76.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.018 0.098 -9999.0 0.0 -0.168 74.0 74.0 CD2AP 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.017 0.098 -9999.0 0.0 -0.168 74.0 74.0 GRB2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.044 0.105 0.227 10.0 -0.199 95.0 105.0 cytoskeleton organization -0.024 0.082 0.212 3.0 -0.194 64.0 67.0 Nephrin/NEPH1 -0.004 0.077 -9999.0 0.0 -0.152 76.0 76.0 Nephrin/NEPH1/ZO-1 0.006 0.095 -9999.0 0.0 -0.178 74.0 74.0