Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q APC 56 (81%) 13 0.92506 1 0.91614 1 0.4046 1 0.36107 1 0.38362 1 0.24223 1 1 1 0.45228 1 0.62415 1 TP53 44 (64%) 25 0.00015 0.0151 0.01496 1 0.53249 1 0.162 1 0.83944 1 0.4868 1 0.65155 1 1 1 0.14602 1 KRAS 38 (55%) 31 0.24852 1 0.0075199 0.729 0.00131 0.13 0.83303 1 0.85237 1 0.04654 1 0.00019 0.019 0.29092 1 0.0056399 0.553 SMAD4 8 (12%) 61 0.078019 1 0.77679 1 0.89323 1 0.15572 1 0.055009 1 0.18596 1 0.228 1 0.31081 1 0.26335 1 FBXW7 9 (13%) 60 0.19049 1 0.40944 1 0.43449 1 0.6885 1 0.63345 1 1 1 0.11907 1 0.80554 1 0.57736 1 NRAS 5 (7%) 64 1 1 0.83933 1 0.11062 1 NA NA NA NA 1 1 1 1 0.097729 1 1 1 ARID1A 5 (7%) 64 0.36413 1 0.39274 1 0.52499 1 0.17145 1 0.53232 1 1 1 1 1 0.31388 1 0.25593 1 RBM10 4 (6%) 65 1 1 0.78916 1 0.46862 1 1 1 0.77995 1 0.01643 1 0.04433 1 0.53311 1 0.56632 1 TCF7L2 7 (10%) 62 0.77984 1 0.20406 1 0.22744 1 0.15037 1 0.29229 1 1 1 0.30626 1 1 1 0.69018 1 ERBB2 4 (6%) 65 1 1 0.87681 1 0.46856 1 0.67521 1 0.40938 1 0.03083 1 0.03491 1 1 1 1 1 KIAA1804 9 (13%) 60 0.51198 1 0.83748 1 0.47354 1 1 1 0.59901 1 1 1 0.75784 1 0.80395 1 0.57412 1 CCDC88C 3 (4%) 66 NA NA NA NA NA NA NA NA NA NA 1 1 0.59349 1 0.43183 1 0.46569 1