Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1p32.1 62 (37%) 107 9.9999e-06 0.00488 9.9999e-06 0.00488 5.9999e-05 0.0259 3e-05 0.0132 0.0054399 1 0.00338 1 0.01561 1 0.00358 1 amp_1q24.3 71 (42%) 98 2e-05 0.00894 0.0017 0.619 0.10828 1 0.01971 1 0.31244 1 0.19887 1 0.22364 1 0.27263 1 amp_3p11.2 40 (24%) 129 0.0096699 1 0.03561 1 0.0064199 1 0.00198 0.709 0.50613 1 0.04368 1 0.27425 1 0.28546 1 amp_5p15.2 73 (43%) 96 8.9999e-05 0.0382 0.0065999 1 0.01481 1 0.00026 0.106 0.86799 1 0.053629 1 0.71258 1 0.80767 1 amp_6p21.1 40 (24%) 129 3e-05 0.0132 9.9999e-06 0.00488 0.00060999 0.242 0.00080999 0.312 0.00316 1 0.00013 0.0546 0.00090999 0.344 0.00098999 0.373 amp_6q24.3 53 (31%) 116 0.00011 0.0464 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 5.9999e-05 0.0259 9.9999e-06 0.00488 9.9999e-06 0.00488 0.00021 0.0865 amp_7q31.1 49 (29%) 120 0.00074999 0.292 0.01526 1 0.054729 1 0.20555 1 0.03845 1 0.0087599 1 0.01956 1 0.00246 0.866 amp_8q21.12 61 (36%) 108 0.054029 1 0.03639 1 0.23568 1 0.60868 1 1 1 0.04526 1 0.58706 1 0.95552 1 amp_11q22.2 26 (15%) 143 0.054909 1 0.057929 1 0.0057899 1 0.13989 1 0.13566 1 0.01779 1 0.085749 1 0.1151 1 amp_12p13.32 32 (19%) 137 0.066519 1 0.39987 1 0.14888 1 0.31415 1 0.097999 1 0.17309 1 0.18661 1 0.24355 1 amp_12p12.1 42 (25%) 127 0.00137 0.506 0.02447 1 0.0094699 1 0.077899 1 0.16143 1 0.0072699 1 0.1439 1 0.091209 1 amp_12q15 64 (38%) 105 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 amp_13q34 31 (18%) 138 0.00149 0.548 0.00080999 0.312 0.077019 1 0.10326 1 0.69854 1 0.16975 1 0.96392 1 0.60681 1 amp_17p11.2 69 (41%) 100 9.9999e-06 0.00488 6.9999e-05 0.03 0.1548 1 0.0112 1 0.51573 1 0.1175 1 0.30485 1 0.65923 1 amp_17q24.3 48 (28%) 121 0.0090699 1 0.00014 0.0584 0.0050799 1 0.00422 1 0.055709 1 0.02898 1 0.10051 1 0.01423 1 amp_19p13.2 68 (40%) 101 2e-05 0.00894 0.04595 1 0.10462 1 0.04696 1 0.819 1 0.47995 1 0.75801 1 0.78487 1 amp_19q12 61 (36%) 108 9.9999e-06 0.00488 0.00082999 0.317 0.01567 1 0.01424 1 0.58814 1 0.00153 0.56 0.3819 1 0.39976 1 amp_20q13.33 68 (40%) 101 7.9999e-05 0.0341 0.00337 1 0.00174 0.632 0.01078 1 0.02558 1 0.00286 0.99 0.01593 1 0.03139 1 amp_21q21.1 51 (30%) 118 2e-04 0.0826 0.00115 0.429 0.13351 1 0.14004 1 0.22363 1 0.01094 1 0.10376 1 0.17693 1 amp_xp21.2 60 (36%) 109 9.9999e-06 0.00488 0.00065999 0.259 0.04117 1 0.13695 1 0.81391 1 0.0246 1 0.50055 1 0.77446 1 amp_xq21.2 25 (15%) 144 0.0074499 1 0.079589 1 0.5997 1 0.23712 1 0.42508 1 0.25455 1 0.55877 1 0.50799 1 del_1p36.32 51 (30%) 118 0.0084399 1 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 del_1p32.3 26 (15%) 143 0.40745 1 0.095939 1 0.98911 1 0.11755 1 0.61697 1 0.28587 1 0.55461 1 0.61987 1 del_1q44 53 (31%) 116 9.9999e-06 0.00488 6.9999e-05 0.03 0.03002 1 0.03416 1 0.068479 1 0.02308 1 0.077119 1 0.13352 1 del_2p25.3 56 (33%) 113 0.00017 0.0707 0.00018 0.0745 3e-05 0.0132 3e-04 0.121 0.00409 1 0.00085999 0.328 0.0056999 1 0.00087999 0.334 del_2q37.3 68 (40%) 101 9.9999e-06 0.00488 0.02173 1 0.10661 1 0.03975 1 0.38606 1 0.39967 1 0.5732 1 0.57774 1 del_2q37.3 70 (41%) 99 9.9999e-06 0.00488 0.0073099 1 0.32634 1 0.01313 1 0.80464 1 0.41746 1 0.95638 1 0.84149 1 del_3p21.31 37 (22%) 132 0.03 1 9.9999e-06 0.00488 0.00013 0.0546 0.00303 1 0.0067099 1 0.00017 0.0707 0.02307 1 0.0062299 1 del_3q29 39 (23%) 130 0.04421 1 0.00034 0.137 0.20653 1 0.54984 1 0.43361 1 0.054159 1 0.24137 1 0.075469 1 del_4q35.1 63 (37%) 106 2e-05 0.00894 0.02555 1 0.56407 1 0.61508 1 0.47422 1 0.45894 1 0.20452 1 0.97694 1 del_6p25.1 61 (36%) 108 0.4079 1 0.04223 1 0.0025 0.877 0.01278 1 0.054359 1 0.00297 1 0.0348 1 0.02018 1 del_6q14.1 49 (29%) 120 0.00028 0.114 0.01123 1 0.30762 1 0.45249 1 0.94555 1 0.70493 1 0.84787 1 0.12278 1 del_6q16.1 48 (28%) 121 0.00442 1 0.21134 1 0.24099 1 0.79212 1 0.86502 1 0.52388 1 0.47638 1 0.058349 1 del_7q36.3 44 (26%) 125 5.9999e-05 0.0259 0.077009 1 0.1324 1 0.44755 1 0.28358 1 0.30811 1 0.33116 1 0.46106 1 del_8p23.3 52 (31%) 117 0.04825 1 9.9999e-06 0.00488 0.0072299 1 0.0094799 1 0.00069999 0.274 0.01959 1 0.00432 1 0.01211 1 del_9p23 58 (34%) 111 0.0067499 1 0.31474 1 0.02704 1 0.27205 1 0.10839 1 0.02967 1 0.096149 1 0.0058299 1 del_9p21.3 72 (43%) 97 0.00129 0.48 0.03825 1 0.00151 0.554 0.02125 1 0.0293 1 0.00075999 0.295 0.00206 0.735 0.00426 1 del_9q34.3 46 (27%) 123 0.00043 0.172 0.13043 1 0.14646 1 0.19919 1 0.15328 1 0.051539 1 0.080769 1 0.03508 1 del_10p15.3 88 (52%) 81 0.00311 1 0.00036 0.145 0.58957 1 0.02838 1 0.79203 1 0.64366 1 0.81822 1 0.74002 1 del_10q23.31 95 (56%) 74 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 0.00026 0.106 5e-05 0.0217 2e-05 0.00894 0.00050999 0.203 del_11p15.5 73 (43%) 96 5e-05 0.0217 0.00079999 0.309 0.92712 1 0.49644 1 0.52232 1 0.92542 1 0.55255 1 0.87894 1 del_11q24.3 75 (44%) 94 9.9999e-06 0.00488 2e-05 0.00894 0.02265 1 0.01391 1 0.0076099 1 0.0080999 1 0.00196 0.704 0.056839 1 del_12p13.1 57 (34%) 112 0.00131 0.485 0.00045 0.18 0.02026 1 0.17832 1 0.074899 1 0.082089 1 0.13958 1 0.10777 1 del_12q12 34 (20%) 135 0.04309 1 0.03269 1 0.83009 1 0.20168 1 0.17052 1 0.66447 1 0.5969 1 0.50576 1 del_13q14.2 121 (72%) 48 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-05 0.0424 9.9999e-06 0.00488 0.00264 0.921 0.0019 0.684 0.0022 0.779 0.00481 1 del_14q24.1 56 (33%) 113 0.52631 1 0.02752 1 0.7504 1 0.00022 0.0902 0.16468 1 0.03148 1 0.050129 1 0.079949 1 del_15q11.2 32 (19%) 137 0.18979 1 0.03837 1 0.00022 0.0902 0.0051699 1 0.01222 1 0.02718 1 0.02013 1 0.04146 1 del_16q12.1 95 (56%) 74 9.9999e-06 0.00488 0.00075999 0.295 0.02427 1 0.02001 1 0.12328 1 0.069229 1 0.02338 1 0.10117 1 del_16q23.1 94 (56%) 75 4e-05 0.0174 0.00068999 0.27 0.0083399 1 0.0068099 1 0.0222 1 0.03294 1 0.00304 1 0.01029 1 del_17p13.1 82 (49%) 87 3e-05 0.0132 9.9999e-05 0.0424 0.00013 0.0546 0.00056999 0.226 0.01611 1 0.00268 0.93 0.00338 1 0.00021 0.0865 del_17q11.2 51 (30%) 118 2e-05 0.00894 9.9999e-06 0.00488 0.00063999 0.252 0.00328 1 0.00107 0.401 0.00114 0.426 0.00044 0.176 0.00104 0.391 del_17q25.3 45 (27%) 124 0.00061999 0.245 0.00325 1 0.055189 1 0.062709 1 0.51442 1 0.16586 1 0.47264 1 0.38524 1 del_18q23 57 (34%) 112 0.0095199 1 0.0329 1 0.01785 1 0.079759 1 0.0352 1 0.083509 1 0.02909 1 0.26922 1 del_19p13.3 50 (30%) 119 2e-05 0.00894 0.00012 0.0505 0.0053999 1 0.01905 1 0.01066 1 0.00186 0.671 0.00207 0.737 0.00081999 0.314 del_19q13.43 73 (43%) 96 0.00042 0.169 0.01264 1 0.10214 1 0.18523 1 0.071379 1 0.02723 1 0.066919 1 0.16143 1 del_21q11.2 31 (18%) 138 0.36163 1 0.40849 1 0.26756 1 0.32783 1 0.01514 1 0.32668 1 0.10158 1 0.13858 1 del_21q22.3 44 (26%) 125 0.069829 1 0.03714 1 0.48226 1 0.57463 1 0.21731 1 0.55263 1 0.38581 1 0.72245 1 del_22q13.31 54 (32%) 115 6.9999e-05 0.03 0.02704 1 0.89078 1 0.11133 1 0.4415 1 0.42794 1 0.6752 1 0.20573 1 del_xp22.33 54 (32%) 115 0.01806 1 0.00158 0.577 0.0097099 1 0.18498 1 0.11919 1 0.14826 1 0.1747 1 0.13817 1 del_xq21.1 80 (47%) 89 0.035 1 0.00086999 0.331 0.00391 1 0.00499 1 0.01367 1 0.0063699 1 0.00452 1 0.01658 1 del_xq27.1 82 (49%) 87 3e-05 0.0132 0.00175 0.633 0.00071999 0.281 0.00226 0.798 0.00262 0.917 0.00266 0.926 0.00212 0.753 0.0013 0.482