Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.029 0.104 0.314 18.0 -9999.0 0.0 18.0 KIRREL -0.037 0.136 -9999.0 0.0 -0.413 19.0 19.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.029 0.105 -9999.0 0.0 -0.315 18.0 18.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.012 0.077 -9999.0 0.0 -0.221 18.0 18.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.006 0.074 -9999.0 0.0 -0.215 18.0 18.0 FYN -0.019 0.075 -9999.0 0.0 -0.207 21.0 21.0 mol:Ca2+ -0.013 0.076 -9999.0 0.0 -0.22 18.0 18.0 mol:DAG -0.012 0.077 -9999.0 0.0 -0.221 18.0 18.0 NPHS2 -0.006 0.026 -9999.0 0.0 -0.198 2.0 2.0 mol:IP3 -0.012 0.077 -9999.0 0.0 -0.221 18.0 18.0 regulation of endocytosis -0.009 0.072 -9999.0 0.0 -0.197 18.0 18.0 Nephrin/NEPH1/podocin/Cholesterol -0.02 0.076 -9999.0 0.0 -0.227 18.0 18.0 establishment of cell polarity -0.029 0.104 -9999.0 0.0 -0.314 18.0 18.0 Nephrin/NEPH1/podocin/NCK1-2 -0.003 0.071 -9999.0 0.0 -0.196 18.0 18.0 Nephrin/NEPH1/beta Arrestin2 -0.008 0.073 -9999.0 0.0 -0.199 18.0 18.0 NPHS1 -0.011 0.053 -9999.0 0.0 -0.212 10.0 10.0 Nephrin/NEPH1/podocin -0.018 0.076 -9999.0 0.0 -0.207 21.0 21.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.012 0.077 -9999.0 0.0 -0.221 18.0 18.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.012 0.077 -9999.0 0.0 -0.221 18.0 18.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.027 0.089 -9999.0 0.0 -0.234 22.0 22.0 cytoskeleton organization -0.006 0.078 -9999.0 0.0 -0.225 18.0 18.0 Nephrin/NEPH1 -0.018 0.072 -9999.0 0.0 -0.216 18.0 18.0 Nephrin/NEPH1/ZO-1 -0.013 0.083 -9999.0 0.0 -0.241 18.0 18.0