Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.012 0.075 0.197 17.0 -9999.0 0.0 17.0 KIRREL 0.026 0.017 0.078 1.0 -0.037 2.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.012 0.075 -9999.0 0.0 -0.198 17.0 17.0 PLCG1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.033 0.069 -9999.0 0.0 -0.148 16.0 16.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.002 0.061 -9999.0 0.0 -0.175 17.0 17.0 FYN -0.004 0.078 0.169 19.0 -0.159 13.0 32.0 mol:Ca2+ 0.034 0.066 -9999.0 0.0 -0.146 15.0 15.0 mol:DAG 0.035 0.066 -9999.0 0.0 -0.147 15.0 15.0 NPHS2 -0.008 0.028 -9999.0 0.0 -0.047 18.0 18.0 mol:IP3 0.035 0.066 -9999.0 0.0 -0.147 15.0 15.0 regulation of endocytosis 0.023 0.06 -9999.0 0.0 -0.143 15.0 15.0 Nephrin/NEPH1/podocin/Cholesterol 0.023 0.063 -9999.0 0.0 -0.143 17.0 17.0 establishment of cell polarity 0.012 0.075 -9999.0 0.0 -0.197 17.0 17.0 Nephrin/NEPH1/podocin/NCK1-2 0.045 0.072 -9999.0 0.0 -0.154 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.024 0.062 -9999.0 0.0 -0.145 15.0 15.0 NPHS1 0.005 0.03 0.079 1.0 -0.047 15.0 16.0 Nephrin/NEPH1/podocin 0.024 0.069 0.176 8.0 -0.145 18.0 26.0 TJP1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.036 0.067 -9999.0 0.0 -0.147 15.0 15.0 CD2AP 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.034 0.071 -9999.0 0.0 -0.149 17.0 17.0 GRB2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.006 0.084 0.17 18.0 -0.172 15.0 33.0 cytoskeleton organization -0.018 0.069 0.203 5.0 -0.195 13.0 18.0 Nephrin/NEPH1 0.014 0.053 -9999.0 0.0 -0.13 17.0 17.0 Nephrin/NEPH1/ZO-1 0.026 0.067 -9999.0 0.0 -0.157 17.0 17.0