Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.015	0.173	0.289	1.0	-0.469	19.0	20.0
IHH	0.021	0.058	0.127	6.0	-0.13	18.0	24.0
SHH Np/Cholesterol/GAS1	0.01	0.044	-9999.0	0.0	-0.146	11.0	11.0
LRPAP1	0.025	0.025	-9999.0	0.0	-0.294	1.0	1.0
dorsoventral neural tube patterning	-0.01	0.044	0.145	11.0	-9999.0	0.0	11.0
SMO/beta Arrestin2	-0.013	0.15	-9999.0	0.0	-0.367	16.0	16.0
SMO	-0.024	0.149	0.224	1.0	-0.381	16.0	17.0
AKT1	-0.001	0.113	-9999.0	0.0	-0.416	7.0	7.0
ARRB2	0.025	0.009	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.002	0.086	-9999.0	0.0	-0.294	13.0	13.0
ADRBK1	0.028	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.023	0.147	0.223	1.0	-0.376	16.0	17.0
STIL	-0.014	0.099	0.18	8.0	-0.249	16.0	24.0
DHH N/PTCH2	0.016	0.076	-9999.0	0.0	-0.21	16.0	16.0
DHH N/PTCH1	0.007	0.116	-9999.0	0.0	-0.279	19.0	19.0
PIK3CA	0.027	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.01	0.069	-9999.0	0.0	-0.294	8.0	8.0
PTHLH	-0.049	0.26	0.323	1.0	-0.737	19.0	20.0
determination of left/right symmetry	-0.023	0.147	0.223	1.0	-0.376	16.0	17.0
PIK3R1	0.028	0.002	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.048	0.257	0.323	1.0	-0.729	19.0	20.0
IHH N/Hhip	0.016	0.087	0.154	2.0	-0.238	13.0	15.0
DHH N/Hhip	0.016	0.085	-9999.0	0.0	-0.205	20.0	20.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.023	0.147	0.223	1.0	-0.376	16.0	17.0
pancreas development	-0.01	0.085	-9999.0	0.0	-0.294	13.0	13.0
HHAT	0.021	0.043	-9999.0	0.0	-0.294	3.0	3.0
PI3K	0.041	0.008	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.011	0.069	-9999.0	0.0	-0.294	8.0	8.0
somite specification	-0.023	0.147	0.223	1.0	-0.376	16.0	17.0
SHH Np/Cholesterol/PTCH1	-0.0	0.097	0.191	1.0	-0.247	18.0	19.0
SHH Np/Cholesterol/PTCH2	0.01	0.049	-9999.0	0.0	-0.156	12.0	12.0
SHH Np/Cholesterol/Megalin	0.01	0.033	-9999.0	0.0	-0.159	3.0	3.0
SHH	-0.016	0.034	0.086	7.0	-0.207	3.0	10.0
catabolic process	0.001	0.121	0.254	1.0	-0.308	19.0	20.0
SMO/Vitamin D3	-0.013	0.12	0.204	1.0	-0.315	17.0	18.0
SHH Np/Cholesterol/Hhip	0.004	0.06	-9999.0	0.0	-0.167	15.0	15.0
LRP2	0.014	0.02	-9999.0	0.0	-9999.0	0.0	0.0
receptor-mediated endocytosis	-0.012	0.119	0.219	1.0	-0.324	14.0	15.0
SHH Np/Cholesterol/BOC	0.006	0.055	-9999.0	0.0	-0.159	15.0	15.0
SHH Np/Cholesterol/CDO	0.016	0.034	-9999.0	0.0	-0.158	5.0	5.0
mesenchymal cell differentiation	-0.004	0.059	0.166	15.0	-9999.0	0.0	15.0
mol:Vitamin D3	0.006	0.102	0.191	7.0	-0.248	18.0	25.0
IHH N/PTCH2	0.02	0.071	0.154	2.0	-0.216	9.0	11.0
CDON	0.022	0.036	-9999.0	0.0	-0.294	2.0	2.0
IHH N/PTCH1	0.008	0.122	0.264	1.0	-0.31	19.0	20.0
Megalin/LRPAP1	0.038	0.023	-9999.0	0.0	-0.206	1.0	1.0
PTCH2	0.009	0.073	-9999.0	0.0	-0.294	9.0	9.0
SHH Np/Cholesterol	-0.005	0.028	-9999.0	0.0	-0.153	3.0	3.0
PTCH1	0.001	0.121	0.255	1.0	-0.309	19.0	20.0
HHIP	-0.01	0.085	-9999.0	0.0	-0.294	13.0	13.0