Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	70 (23%)	229	0.096129	1	0.95492	1	0.89759	1	0.92049	1	0.2036	1	0.34447	1	0.6488	1	0.95515	1	0.85129	1	0.66312	1
1q gain	136 (45%)	163	9.9999e-06	0.00788	0.085509	1	0.28499	1	0.56091	1	0.03574	1	0.069069	1	0.22361	1	0.04472	1	0.14171	1	0.17029	1
2p gain	58 (19%)	241	0.00036	0.273	0.53517	1	0.63946	1	0.88971	1	0.01111	1	0.00031	0.235	0.083579	1	0.00118	0.884	0.03203	1	0.00055999	0.423
2q gain	56 (19%)	243	2e-05	0.0154	0.86171	1	0.76062	1	0.53332	1	0.00082999	0.626	6.9999e-05	0.0535	0.057579	1	0.00024	0.182	0.0091499	1	5e-05	0.0384
3p gain	48 (16%)	251	0.66142	1	0.11658	1	0.03781	1	0.02073	1	0.13804	1	0.73578	1	0.6223	1	0.10892	1	0.57048	1	0.63645	1
3q gain	58 (19%)	241	0.27157	1	0.34695	1	0.01906	1	0.0448	1	0.0080299	1	0.4455	1	0.34048	1	0.22857	1	0.56174	1	1	1
4p gain	44 (15%)	255	0.0095699	1	0.15779	1	0.30857	1	0.85693	1	0.68552	1	0.36151	1	0.42139	1	0.02331	1	0.20324	1	0.21706	1
4q gain	37 (12%)	262	0.01926	1	0.052319	1	0.26392	1	0.93355	1	0.73957	1	0.47076	1	0.57931	1	0.02106	1	0.47573	1	0.3629	1
5p gain	58 (19%)	241	0.0135	1	0.36887	1	0.89316	1	0.54239	1	0.22112	1	0.8786	1	0.141	1	0.28508	1	0.14803	1	0.56391	1
5q gain	36 (12%)	263	0.04753	1	0.62324	1	0.41161	1	0.23896	1	0.75262	1	0.67797	1	0.51919	1	0.50394	1	0.02338	1	0.14765	1
6p gain	117 (39%)	182	9.9999e-06	0.00788	0.00415	1	0.8453	1	0.1684	1	0.63379	1	0.1162	1	0.02455	1	0.00261	1	0.0137	1	0.00466	1
6q gain	39 (13%)	260	0.02151	1	0.16749	1	0.91852	1	0.24698	1	0.95298	1	0.81107	1	0.84642	1	0.18938	1	0.53562	1	0.25011	1
7p gain	161 (54%)	138	9.9999e-06	0.00788	0.5865	1	0.45749	1	0.37393	1	0.02991	1	0.17506	1	0.48849	1	0.777	1	0.58148	1	0.4142	1
7q gain	159 (53%)	140	9.9999e-06	0.00788	0.38541	1	0.69051	1	0.51671	1	0.0057699	1	0.02255	1	0.67157	1	0.51457	1	0.77685	1	0.40728	1
8p gain	99 (33%)	200	5e-05	0.0384	0.094269	1	0.60931	1	0.84305	1	0.01636	1	0.74268	1	0.45237	1	0.96245	1	0.058019	1	0.48108	1
8q gain	141 (47%)	158	2e-05	0.0154	0.00332	1	0.65059	1	0.85097	1	0.00229	1	0.58913	1	0.4805	1	0.73845	1	0.094379	1	0.1818	1
9p gain	15 (5%)	284	0.34454	1	0.27312	1	0.37627	1	0.83796	1	0.39873	1	0.86986	1	0.97316	1	0.55236	1	0.94601	1	0.42658	1
9q gain	20 (7%)	279	0.17035	1	0.87698	1	0.13466	1	0.92829	1	0.47739	1	0.89677	1	0.87531	1	0.89602	1	0.86479	1	0.63613	1
10p gain	10 (3%)	289	0.88895	1	0.8508	1	0.86886	1	0.54779	1	0.84953	1	0.312	1	0.21971	1	0.25276	1	0.84042	1	0.51831	1
11p gain	30 (10%)	269	0.01348	1	0.37067	1	0.085079	1	0.18827	1	0.00181	1	0.3086	1	0.11668	1	0.00281	1	0.14763	1	0.04474	1
11q gain	26 (9%)	273	0.00053999	0.408	0.28064	1	0.076589	1	0.087329	1	0.00433	1	0.25711	1	0.059649	1	5.9999e-05	0.0459	0.19603	1	0.02225	1
12p gain	50 (17%)	249	0.00416	1	0.3272	1	0.37365	1	0.36597	1	0.02151	1	0.12911	1	0.94164	1	0.44604	1	0.9228	1	0.97445	1
12q gain	33 (11%)	266	0.063479	1	0.69039	1	0.61704	1	0.058369	1	0.53586	1	0.18535	1	0.88666	1	0.26861	1	0.6132	1	0.82336	1
13q gain	75 (25%)	224	9.9999e-06	0.00788	9.9999e-06	0.00788	0.50287	1	0.17861	1	0.00131	0.98	0.01041	1	0.92546	1	0.85327	1	0.64181	1	0.88169	1
14q gain	32 (11%)	267	0.31045	1	0.11524	1	0.49523	1	0.19705	1	0.81342	1	0.36804	1	0.89668	1	0.61043	1	0.64309	1	0.97563	1
15q gain	69 (23%)	230	9.9999e-06	0.00788	0.32438	1	0.84491	1	0.79719	1	0.01239	1	0.069239	1	0.21127	1	0.03645	1	0.49941	1	0.02301	1
16p gain	41 (14%)	258	0.090849	1	0.0195	1	1	1	0.79021	1	0.00012	0.0914	0.01031	1	0.19139	1	0.26347	1	0.095859	1	0.079009	1
16q gain	35 (12%)	264	0.27475	1	0.056329	1	0.26556	1	0.80518	1	9.9999e-05	0.0763	0.0059799	1	0.41152	1	0.098819	1	0.16198	1	0.063189	1
17p gain	34 (11%)	265	0.0069699	1	0.0092499	1	0.60125	1	0.48282	1	0.19647	1	0.26072	1	0.62655	1	0.38506	1	0.65655	1	0.40949	1
17q gain	59 (20%)	240	0.062669	1	0.078069	1	0.081499	1	0.18229	1	0.67176	1	0.97828	1	0.22534	1	0.42179	1	0.059909	1	0.0055599	1
18p gain	48 (16%)	251	0.04289	1	0.81237	1	0.2024	1	0.40546	1	0.296	1	0.33044	1	0.80255	1	0.7227	1	0.3444	1	0.47833	1
18q gain	39 (13%)	260	0.02156	1	0.9284	1	0.40199	1	0.60006	1	0.67619	1	1	1	0.65035	1	0.81503	1	0.44358	1	0.81576	1
19p gain	43 (14%)	256	0.25342	1	0.080739	1	0.25125	1	0.79793	1	0.0057599	1	0.073909	1	0.78235	1	0.71017	1	0.95409	1	0.63041	1
19q gain	44 (15%)	255	0.12938	1	0.01057	1	0.29594	1	1	1	0.00083999	0.633	0.066839	1	0.72336	1	0.60716	1	0.65337	1	0.68446	1
20p gain	124 (41%)	175	9.9999e-06	0.00788	0.01885	1	0.84228	1	0.98452	1	0.00014	0.107	0.00085999	0.647	0.32012	1	0.14379	1	0.094639	1	0.18808	1
20q gain	147 (49%)	152	9.9999e-06	0.00788	0.03806	1	0.94032	1	0.97397	1	0.00229	1	0.01545	1	0.64592	1	0.17622	1	0.25222	1	0.36896	1
21q gain	54 (18%)	245	0.43159	1	0.085399	1	0.88856	1	0.52998	1	0.41666	1	0.11943	1	0.44879	1	0.931	1	0.73108	1	0.88859	1
22q gain	107 (36%)	192	0.0051099	1	0.34163	1	0.89503	1	0.94436	1	0.15387	1	0.04094	1	0.80625	1	0.37244	1	0.46734	1	0.74382	1
xq gain	32 (11%)	267	0.0078599	1	0.03596	1	0.68913	1	0.88134	1	0.1605	1	0.12943	1	0.82522	1	0.4392	1	0.8088	1	0.62131	1
1p loss	36 (12%)	263	0.24441	1	0.003	1	0.38615	1	0.099339	1	0.02881	1	0.067409	1	0.17123	1	0.59626	1	0.487	1	0.56089	1
1q loss	20 (7%)	279	0.10172	1	0.41233	1	0.96897	1	0.46067	1	0.10016	1	0.64731	1	0.73317	1	0.19497	1	0.38192	1	0.40156	1
2p loss	38 (13%)	261	0.19087	1	0.27937	1	0.0472	1	0.01515	1	0.37998	1	0.1016	1	0.00209	1	0.01326	1	0.0094299	1	0.03821	1
2q loss	39 (13%)	260	0.03473	1	0.060249	1	0.01168	1	0.00178	1	0.16105	1	0.27222	1	0.0071499	1	0.02894	1	0.0067899	1	0.062909	1
3p loss	48 (16%)	251	0.26858	1	0.66125	1	0.4832	1	0.32044	1	0.0287	1	0.24503	1	0.01921	1	0.49548	1	0.03103	1	0.086519	1
3q loss	37 (12%)	262	0.31302	1	0.2737	1	0.38171	1	0.3496	1	0.17285	1	0.36097	1	0.14471	1	0.48163	1	0.16623	1	0.68551	1
4p loss	64 (21%)	235	0.77597	1	0.1046	1	0.35266	1	0.9692	1	0.28869	1	0.18234	1	0.6705	1	0.01319	1	0.31834	1	0.1424	1
4q loss	66 (22%)	233	0.4036	1	0.03032	1	0.48167	1	0.75119	1	0.12514	1	0.19659	1	0.57641	1	0.00379	1	0.10018	1	0.01577	1
5p loss	66 (22%)	233	0.21735	1	0.46714	1	0.79992	1	0.83255	1	0.93712	1	0.86998	1	0.75297	1	0.71422	1	0.6926	1	0.65491	1
5q loss	84 (28%)	215	0.01712	1	0.10798	1	0.43887	1	0.28739	1	0.78064	1	0.12399	1	0.97913	1	0.8758	1	0.77389	1	0.698	1
6p loss	56 (19%)	243	0.00212	1	0.70566	1	0.90308	1	0.29468	1	0.01211	1	0.10543	1	0.053849	1	0.02925	1	0.090799	1	0.04994	1
6q loss	146 (49%)	153	9.9999e-06	0.00788	0.062049	1	0.99242	1	0.36067	1	0.01066	1	0.03896	1	0.52144	1	0.55535	1	0.78759	1	0.10231	1
7p loss	16 (5%)	283	0.79987	1	0.00384	1	0.094169	1	0.55933	1	0.7131	1	0.87073	1	0.63999	1	0.88137	1	0.55847	1	0.85737	1
7q loss	15 (5%)	284	0.77457	1	0.00248	1	0.33955	1	0.43581	1	0.35447	1	0.50015	1	0.77674	1	0.78021	1	0.2483	1	0.77241	1
8p loss	53 (18%)	246	0.71168	1	0.62103	1	0.087319	1	0.39407	1	0.31635	1	0.95425	1	0.26594	1	0.057009	1	0.38759	1	0.50666	1
8q loss	21 (7%)	278	0.37324	1	0.11036	1	0.31522	1	0.53589	1	0.46701	1	0.81059	1	0.22465	1	0.6269	1	0.2131	1	0.23521	1
9p loss	197 (66%)	102	0.03013	1	0.050349	1	0.64636	1	0.45046	1	0.00285	1	0.01157	1	0.02843	1	0.15653	1	0.88166	1	0.3106	1
9q loss	154 (52%)	145	0.85485	1	0.04475	1	0.97277	1	0.1087	1	0.03516	1	0.58419	1	0.062639	1	0.01591	1	0.64041	1	0.62213	1
10p loss	167 (56%)	132	9.9999e-06	0.00788	0.03178	1	0.89604	1	0.4537	1	5e-05	0.0384	0.00099999	0.75	0.35988	1	0.10469	1	0.56971	1	0.78069	1
10q loss	185 (62%)	114	9.9999e-06	0.00788	0.03181	1	0.91794	1	0.2008	1	4e-05	0.0308	0.00046	0.348	0.17768	1	0.01521	1	0.74612	1	0.93502	1
11p loss	102 (34%)	197	9.9999e-06	0.00788	0.056559	1	0.5849	1	0.50859	1	0.30569	1	0.084999	1	0.65393	1	0.13781	1	0.52352	1	0.42476	1
11q loss	117 (39%)	182	9.9999e-06	0.00788	0.2865	1	0.96161	1	0.76249	1	0.11466	1	0.16433	1	0.63913	1	0.45458	1	1	1	0.26625	1
12p loss	46 (15%)	253	0.01452	1	0.03139	1	0.7665	1	0.68197	1	0.04886	1	0.89927	1	0.40677	1	0.17345	1	0.4828	1	0.75959	1
12q loss	52 (17%)	247	0.00405	1	0.04299	1	0.99192	1	0.92342	1	0.057459	1	0.39225	1	0.32902	1	0.43839	1	0.83389	1	0.93978	1
13q loss	65 (22%)	234	9.9999e-06	0.00788	0.00226	1	0.04016	1	0.37755	1	0.92156	1	0.16269	1	0.83148	1	0.64018	1	0.81793	1	0.27441	1
14q loss	93 (31%)	206	9.9999e-06	0.00788	0.65005	1	0.41088	1	0.27085	1	0.00097999	0.736	0.35138	1	0.02292	1	0.93732	1	0.01669	1	0.27278	1
15q loss	42 (14%)	257	0.00183	1	0.14288	1	0.12675	1	0.059189	1	0.297	1	0.50404	1	0.81951	1	0.70485	1	0.73927	1	0.22098	1
16p loss	58 (19%)	241	0.11332	1	0.067669	1	0.04609	1	0.51989	1	0.01965	1	0.50617	1	0.21745	1	0.30596	1	0.1621	1	0.30706	1
16q loss	87 (29%)	212	0.053129	1	0.16949	1	0.0112	1	0.84936	1	0.01945	1	0.3087	1	0.13728	1	0.093679	1	0.15633	1	0.11417	1
17p loss	101 (34%)	198	0.71834	1	0.17672	1	0.75643	1	0.48644	1	0.2896	1	0.45401	1	0.75901	1	0.45998	1	0.74397	1	0.70936	1
17q loss	50 (17%)	249	0.61738	1	0.59212	1	0.17411	1	0.40511	1	0.85472	1	1	1	0.52623	1	0.66117	1	0.84693	1	0.6868	1
18p loss	86 (29%)	213	0.30227	1	0.35762	1	0.37897	1	0.51338	1	0.01835	1	0.288	1	0.054989	1	0.42382	1	0.80049	1	0.31142	1
18q loss	82 (27%)	217	0.086149	1	0.35634	1	0.39725	1	0.52504	1	0.4378	1	0.5288	1	0.34741	1	0.18094	1	0.98546	1	0.50657	1
19p loss	62 (21%)	237	0.00411	1	0.10391	1	0.78513	1	0.088009	1	0.087069	1	0.19194	1	0.44419	1	0.57508	1	0.20569	1	0.48942	1
19q loss	60 (20%)	239	0.0062599	1	0.04111	1	0.97765	1	0.083609	1	0.26098	1	0.20112	1	0.83182	1	0.72609	1	0.48805	1	0.39554	1
20p loss	18 (6%)	281	0.44666	1	0.95337	1	0.23469	1	0.77159	1	0.75215	1	0.081579	1	0.14636	1	0.13389	1	0.46453	1	0.2784	1
20q loss	7 (2%)	292	0.50022	1	0.49222	1	NA	NA	NA	NA	0.23537	1	0.01381	1	0.28844	1	0.94953	1	0.79788	1	0.71148	1
21q loss	58 (19%)	241	0.14308	1	0.41275	1	0.46977	1	0.93201	1	0.50903	1	0.89541	1	0.063519	1	0.51582	1	0.04294	1	0.22049	1
22q loss	32 (11%)	267	0.1807	1	0.44281	1	0.95495	1	0.93875	1	0.6857	1	0.29052	1	0.76665	1	0.72524	1	0.94161	1	0.98227	1
xq loss	74 (25%)	225	0.02413	1	4e-05	0.0308	0.30407	1	0.085919	1	0.0018	1	0.03185	1	0.04188	1	0.19934	1	0.2285	1	0.70877	1