Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.015 0.087 0.237 37.0 -9999.0 0.0 37.0 KIRREL 0.002 0.067 -9999.0 0.0 -0.463 6.0 6.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.015 0.087 -9999.0 0.0 -0.237 37.0 37.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.019 -9999.0 0.0 -0.324 1.0 1.0 WASL 0.013 0.027 -9999.0 0.0 -0.45 1.0 1.0 Nephrin/NEPH1/podocin/CD2AP -0.001 0.07 -9999.0 0.0 -0.282 9.0 9.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.012 0.048 -9999.0 0.0 -0.239 7.0 7.0 FYN -0.002 0.056 -9999.0 0.0 -0.263 6.0 6.0 mol:Ca2+ 0.001 0.062 -9999.0 0.0 -0.272 6.0 6.0 mol:DAG 0.002 0.063 -9999.0 0.0 -0.273 6.0 6.0 NPHS2 -0.001 0.011 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.002 0.063 -9999.0 0.0 -0.273 6.0 6.0 regulation of endocytosis 0.007 0.055 -9999.0 0.0 -0.242 6.0 6.0 Nephrin/NEPH1/podocin/Cholesterol -0.007 0.062 -9999.0 0.0 -0.28 6.0 6.0 establishment of cell polarity -0.015 0.087 -9999.0 0.0 -0.237 37.0 37.0 Nephrin/NEPH1/podocin/NCK1-2 0.011 0.058 -9999.0 0.0 -0.243 6.0 6.0 Nephrin/NEPH1/beta Arrestin2 0.008 0.056 -9999.0 0.0 -0.244 6.0 6.0 NPHS1 -0.028 0.103 -9999.0 0.0 -0.322 33.0 33.0 Nephrin/NEPH1/podocin -0.001 0.057 -9999.0 0.0 -0.264 6.0 6.0 TJP1 0.007 0.059 -9999.0 0.0 -0.45 5.0 5.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.002 0.063 -9999.0 0.0 -0.274 6.0 6.0 CD2AP 0.01 0.046 -9999.0 0.0 -0.45 3.0 3.0 Nephrin/NEPH1/podocin/GRB2 0.002 0.063 -9999.0 0.0 -0.274 6.0 6.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.01 0.072 -9999.0 0.0 -0.257 13.0 13.0 cytoskeleton organization 0.014 0.053 -9999.0 0.0 -0.265 6.0 6.0 Nephrin/NEPH1 -0.007 0.06 -9999.0 0.0 -0.268 6.0 6.0 Nephrin/NEPH1/ZO-1 -0.005 0.079 -9999.0 0.0 -0.303 11.0 11.0