Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.027 0.196 -9999.0 0.0 -0.54 32.0 32.0 MAP3K8 -0.001 0.077 -9999.0 0.0 -0.376 12.0 12.0 FOS -0.038 0.2 -9999.0 0.0 -0.552 33.0 33.0 PRKCA -0.002 0.085 -9999.0 0.0 -0.418 12.0 12.0 PTPN7 -0.041 0.147 -9999.0 0.0 -0.415 40.0 40.0 HRAS 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.047 0.149 -9999.0 0.0 -0.399 45.0 45.0 NRAS 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.028 0.011 -9999.0 0.0 -0.15 1.0 1.0 MAPK3 -0.04 0.193 -9999.0 0.0 -0.589 29.0 29.0 MAP2K1 -0.021 0.149 -9999.0 0.0 -0.409 34.0 34.0 ELK1 0.015 0.001 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.026 0.142 -9999.0 0.0 -0.39 36.0 36.0 mol:GTP 0.0 0.001 -9999.0 0.0 -0.003 8.0 8.0 MAPK1 -0.04 0.193 -9999.0 0.0 -0.577 30.0 30.0 RAF1 -0.023 0.14 -9999.0 0.0 -0.392 34.0 34.0 KRAS 0.013 0.019 -9999.0 0.0 -0.323 1.0 1.0