Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	-0.034	0.094	-9999.0	0.0	-0.185	82.0	82.0
epithelial cell differentiation	-0.004	0.101	-9999.0	0.0	-0.165	81.0	81.0
CYFIP2	0.014	0.072	0.124	3.0	-0.331	12.0	15.0
ENAH	-0.047	0.065	-9999.0	0.0	-0.237	7.0	7.0
EGFR	0.021	0.071	-9999.0	0.0	-0.331	10.0	10.0
EPHA2	0.022	0.052	0.124	5.0	-0.331	6.0	11.0
MYO6	-0.049	0.079	0.202	6.0	-0.166	78.0	84.0
CTNNB1	0.029	0.003	-9999.0	0.0	-9999.0	0.0	0.0
ABI1/Sra1/Nap1	0.042	0.052	-9999.0	0.0	-0.189	12.0	12.0
AQP5	-0.022	0.077	0.328	2.0	-0.406	1.0	3.0
CTNND1	0.029	0.003	-9999.0	0.0	-9999.0	0.0	0.0
mol:PI-4-5-P2	-0.046	0.076	0.2	6.0	-0.16	77.0	83.0
regulation of calcium-dependent cell-cell adhesion	-0.045	0.081	0.211	6.0	-0.163	81.0	87.0
EGF	-0.03	0.144	-9999.0	0.0	-0.331	54.0	54.0
NCKAP1	0.029	0.002	-9999.0	0.0	-9999.0	0.0	0.0
AQP3	-0.052	0.117	0.385	1.0	-0.337	28.0	29.0
cortical microtubule organization	-0.004	0.101	-9999.0	0.0	-0.165	81.0	81.0
GO:0000145	-0.046	0.071	0.189	6.0	-0.153	77.0	83.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	-0.0	0.105	-9999.0	0.0	-0.167	81.0	81.0
MLLT4	0.022	0.037	-9999.0	0.0	-0.331	3.0	3.0
ARF6/GDP	-0.055	0.06	-9999.0	0.0	-0.156	72.0	72.0
ARF6	0.028	0.004	-9999.0	0.0	-9999.0	0.0	0.0
Ephrin A1/EPHA2/NCK1/GIT1	0.058	0.046	-9999.0	0.0	-0.173	7.0	7.0
mol:Ca2+	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	-0.035	0.07	0.2	5.0	-9999.0	0.0	5.0
PVRL2	0.029	0.003	-9999.0	0.0	-9999.0	0.0	0.0
ZYX	-0.043	0.074	0.205	5.0	-0.162	71.0	76.0
ARF6/GTP	0.064	0.047	-9999.0	0.0	-0.163	7.0	7.0
CDH1	-0.067	0.164	-9999.0	0.0	-0.331	82.0	82.0
EGFR/EGFR/EGF/EGF	-0.042	0.122	-9999.0	0.0	-0.188	112.0	112.0
RhoA/GDP	-0.002	0.099	-9999.0	0.0	-0.16	81.0	81.0
actin cytoskeleton organization	-0.053	0.079	0.186	6.0	-0.169	70.0	76.0
IGF-1R heterotetramer	0.026	0.03	-9999.0	0.0	-0.33	2.0	2.0
GIT1	0.028	0.005	-9999.0	0.0	-9999.0	0.0	0.0
IGF1R	0.026	0.03	-9999.0	0.0	-0.331	2.0	2.0
IGF1	0.01	0.085	0.124	6.0	-0.331	17.0	23.0
DIAPH1	-0.037	0.218	-9999.0	0.0	-0.542	39.0	39.0
Wnt receptor signaling pathway	0.004	0.101	0.165	81.0	-9999.0	0.0	81.0
RHOA	0.029	0.003	-9999.0	0.0	-9999.0	0.0	0.0
RhoA/GTP	-0.055	0.061	-9999.0	0.0	-0.158	72.0	72.0
CTNNA1	0.027	0.007	-9999.0	0.0	-9999.0	0.0	0.0
VCL	-0.054	0.08	0.187	6.0	-0.172	70.0	76.0
EFNA1	0.025	0.022	-9999.0	0.0	-0.331	1.0	1.0
LPP	-0.051	0.074	0.195	6.0	-0.158	80.0	86.0
Ephrin A1/EPHA2	-0.009	0.093	-9999.0	0.0	-0.16	77.0	77.0
SEC6/SEC8	-0.05	0.062	-9999.0	0.0	-0.156	73.0	73.0
MGAT3	-0.046	0.082	0.212	6.0	-0.165	81.0	87.0
HGF/MET	-0.025	0.112	-9999.0	0.0	-0.18	94.0	94.0
HGF	0.019	0.069	-9999.0	0.0	-0.331	10.0	10.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	-0.034	0.095	-9999.0	0.0	-0.187	82.0	82.0
actin cable formation	-0.018	0.104	0.263	14.0	-0.255	10.0	24.0
KIAA1543	-0.05	0.075	0.191	6.0	-0.158	83.0	89.0
KIFC3	-0.05	0.074	0.236	3.0	-0.162	79.0	82.0
NCK1	0.028	0.005	-9999.0	0.0	-9999.0	0.0	0.0
EXOC3	0.026	0.009	-9999.0	0.0	-9999.0	0.0	0.0
ACTN1	-0.049	0.078	0.202	6.0	-0.162	81.0	87.0
NCK1/GIT1	0.041	0.01	-9999.0	0.0	-9999.0	0.0	0.0
mol:GDP	-0.004	0.101	-9999.0	0.0	-0.165	81.0	81.0
EXOC4	0.025	0.009	-9999.0	0.0	-9999.0	0.0	0.0
STX4	-0.048	0.077	0.202	6.0	-0.162	79.0	85.0
PIP5K1C	-0.047	0.077	0.202	6.0	-0.162	77.0	83.0
LIMA1	0.028	0.004	-9999.0	0.0	-9999.0	0.0	0.0
ABI1	0.026	0.009	-9999.0	0.0	-9999.0	0.0	0.0
ROCK1	-0.037	0.092	0.348	4.0	-0.239	1.0	5.0
adherens junction assembly	-0.045	0.087	0.269	4.0	-0.291	9.0	13.0
IGF-1R heterotetramer/IGF1	-0.018	0.103	-9999.0	0.0	-0.166	93.0	93.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.035	0.03	-9999.0	0.0	-0.231	3.0	3.0
MET	-0.007	0.11	0.124	11.0	-0.331	30.0	41.0
PLEKHA7	-0.05	0.081	0.202	6.0	-0.165	83.0	89.0
mol:GTP	0.056	0.045	-9999.0	0.0	-0.172	7.0	7.0
establishment of epithelial cell apical/basal polarity	-0.02	0.109	0.309	9.0	-9999.0	0.0	9.0
cortical actin cytoskeleton stabilization	-0.034	0.094	-9999.0	0.0	-0.185	82.0	82.0
regulation of cell-cell adhesion	-0.053	0.079	0.186	6.0	-0.169	70.0	76.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	-0.034	0.095	-9999.0	0.0	-0.187	82.0	82.0